Mondor's Disease of Chest Wall: A Case Report

Background: Mondor's disease (MD) is a rare benign and self-limited entity characterized by superficial thrombophlebitis of a vein in special regions. It may be secondary to trauma, malignancy, surgery, excessive physical activity or hyperviscosity. Diagnosis of MD is often based on history and physical examination. Case presentation: Here we present a rare case of Mondor's disease of chest wall with a pain and subcutaneous cord-like induration of right lateral chest. Ultrasonography revealed a superficial venous thrombosis of right thoracoepigastric vein. After treatment of aspirin for 2 weeks, chest pain was obviously relieved, and the lesion completely resolved approximately 6 weeks after presentation. Conclusions: Mondor’s disease could spontaneously resolved after several weeks and excessive medical intervention should be avoided.

Mondor’s disease of the penis due to asymptomatic infective prostatitis provoking episodes of secondary sclerotizing lymphangitis

Mondor’s disease of the penis is an under-reported condition caused by superficial thrombophlebitis of the dorsal vein or thrombosis of the deep venous network of the penis. This is a benign, self-limiting condition, characterized by a sudden, indurated swelling of the aforementioned veins. The possible causes comprise traumatism, neoplasms, excessive sexual activity, or coagulation inherited deficit. An accompanied lymphangitis is discussed, eventually as a distinct variety. The differential diagnosis must be established by the means of ultrasound, which is the imaging diagnostic technique of choice. We describe the case of Mondor’s sclerotizing lymphangitis secondary to recurrent episodes of genitourinary infection previously diagnosed as recurrent superficial Mondor thrombophlebitis of the penis.

A case of COVID-19 with superficial thrombophlebitis caused by an indwelling peripheral venous catheter

Background: COVID-19 is caused by SARS-CoV-2 infection, and cytokine storm and microthrombus formation affect the severity of the disease, which is often complicated by venous thrombosis due to a systemic hypercoagulable state. On the other hand, indwelling peripheral venous catheters can cause catheter-related bloodstream infections and venous thrombus formation, albeit less frequently. Case presentation: A 53-year-old man was admitted to the hospital with severe COVID-19. He had bilateral pneumonia and required ventilator management but recovered after steroid and anticoagulation. On the 26th day after onset, redness, swelling, and pain developed around the insertion site of the catheter placed in the cephalic vein of the left forearm. Vascular ultrasonography revealed a thrombus in this vein accompanied by inflammation in the surrounding tissues. Catheter-related bloodstream infection was suspected and vancomycin was administered; however, blood cultures were negative, leading to the diagnosis of non-infectious superficial thrombophlebitis. The skin findings improved after removal of the peripheral venous catheter. Conclusions: This case suggested that catheter placement in peripheral veins during COVID-19 treatment increases the risk of thrombus formation. Although anticoagulant therapy is able to control the systemic hypercoagulable state caused by COVID-19, indwelling catheters can induce a local hypercoagulable state, leading to superficial thrombophlebitis.

The Success Rate and Complications of Post-radiofrequency Ablation in Patients With Small Saphenous Insufficiency

Aims: This study aimed to determine the success rate and complications occurring after Radiofrequency Ablation (RFA) in patients with small saphenous insufficiency who underwent RFA in Rasht. Methods & Materials: Patients with small saphenous vein insufficiency who underwent RFA were explored respecting success rate and potential complications, such as pain, hematoma, neuropathy, Endothermal Heat-Induced Thrombosis (EHIT), and skin burns. The study subjects were assessed 2 weeks after the procedure. Reconanalysis was followed up in the study participants by ultrasound at 2 weeks, 3-6 months, and the first year after RFA. Findings: This study examined 62 patients. A 100% success rate was reported and no case of reflux was observed in the first control ultrasound 2 weeks after RFA. The mean pain score significantly decreased (P<0.001). Besides, in one year, 3 cases of recanalization, 7 cases of EHIT, 9 cases of neuropathy, and 1 case of superficial thrombophlebitis were reported; no case of skin burn was observed. Conclusion: Considering the 100% success rate and slight adverse effects of this method, such as pain and recanalization, RFA is an acceptable approach. Furthermore, the incidence of EHIT should be considered.

Case Report: Glomus Tumor of the Thigh

Glomus tumors are small, painful benign tumors that occur primarily in the subungual region of the hand. The presentation of glomus tumors in areas other than the hand is rare, but have been reported. Patients with glomus tumors have a prolonged history of focal pain, tenderness, and cold hypersensitivity. However, as all 3 symptoms may not present simultaneously, it can present a diagnostic challenge to clinicians and imagers, often remaining undiagnosed or misdiagnosed for many years. We report a case of an extradigital glomus tumor of the right thigh that was initially diagnosed as focal superficial thrombophlebitis. The diagnosis of glomus tumor was pathologically proven.