scholarly journals Simultaneous Pleural and Pericardial Effusion as First Clinical Manifestations of Giant Cell Arteritis: A Case Report

Cureus ◽  
2020 ◽  
Author(s):  
Vasiliki E Georgakopoulou ◽  
Dimitrios Mermigkis ◽  
Ourania Kairi ◽  
Anna Garmpi ◽  
Xanthi Tsiafaki
Keyword(s):  
Case Report ◽  
Pericardial Effusion ◽  
Giant Cell Arteritis ◽  
Giant Cell ◽  
Clinical Manifestations

A case report of pericardial effusion in giant cell arteritis

2020 ◽  
pp. 149-151
Author(s):  
Fotis Konstantinou ◽  
Natalia Vallianou ◽  
Victoria Gennimata ◽  
Angelos Konstantinou ◽  
Evangelos Kokkinakis
Keyword(s):  
Case Report ◽  
Pericardial Effusion ◽  
Giant Cell Arteritis ◽  
Giant Cell

Polymyalgia Rheumatica - a Disease of the Elderly

2018 ◽  
Vol 69 (1) ◽  
pp. 152-154
Author(s):  
Vasilica Cristescu ◽  
Aurelia Romila ◽  
Luana Andreea Macovei
Keyword(s):  
Giant Cell Arteritis ◽  
Giant Cell ◽  
Polymyalgia Rheumatica ◽  
Temporal Arteritis ◽  
Viral Infections ◽  
Clinical Manifestations ◽  
The Elderly ◽  
Clinical Aspects ◽  
Immune Disorder ◽  
Markers Of Inflammation

Polymyalgia rheumatica is a disease that occurs mostly in the elderly and is rarely seen in patients less than 50 years of age. Polymyalgia rheumatica is a vasculitis, which manifests itself as an inflammatory disease of the vascular wall that can affect any type of blood vessel, regardless of its size. It has been considered a form of giant cell arteritis, involving primarily large and medium arteries and to a lesser extent the arterioles. Clinical manifestations are caused by the generic pathogenic process and depend on the characteristics of the damaged organ. PMR is a senescence-related immune disorder. It has been defined as a stand-alone condition and a syndrome referred to as rheumatic polyarteritis with manifestations of giant cell arteritis (especially in cases of Horton�s disease and temporal arteritis) which are commonly associated with polymyalgia. The clinical presentation is clearly dominated by the painful girdle syndrome, with a feeling of general discomfort. Polymyalgia and temporal arteritis may coexist or be consecutive to each other in the same patient, as in most of our patients. The present study describes 3 cases of polymyalgia rheumatica, admitted to the Clinic of Rheumatology of Sf. Apostol Andrei Hospital, Galati. The cases were compared with the literature. Two clinical aspects (polymyalgia rheumatica and/or Horton�s disease) and the relationship between them were also considered. Polymyalgia rheumatica is currently thought to have a multifactorial etiology, in which the following factors play a role: genetic factors or hereditary predisposition (some individuals are more prone to this disease), immune factors and viral infections (triggers of the disease). Other risk factors of polymyalgia rheumatica include age over 50 years and the association with giant cell arteritis. The characteristic feature of the disease is girdle pain, with intense stiffness of at least one hour�s duration. Markers of inflammation, erythrocyte sedimentation rate and C-reactive protein are almost always increased at the onset of the disease. Diseases that can mimic the clinical picture of polymyalgia rheumatica are neoplasia, infections, metabolic disorders of the bone and endocrine diseases.

Giant cell arteritis--a case report

BDJ ◽  
1997 ◽  
Vol 183 (7) ◽  
pp. 260-262 ◽  
Author(s):  
P P Nixon ◽  
M Payne ◽  
C D Franklin
Keyword(s):  
Case Report ◽  
Giant Cell Arteritis ◽  
Giant Cell

Giant cell arteritis with normal inflammatory markers: case report and review of the literature

2020 ◽  
Vol 39 (10) ◽  
pp. 3115-3125 ◽  
Author(s):  
Patrícia Martins ◽  
Vítor Teixeira ◽  
Filipa Jorge Teixeira ◽  
Mário Canastro ◽  
Ana Palha ◽  
...  
Keyword(s):  
Case Report ◽  
Giant Cell Arteritis ◽  
Giant Cell ◽  
Inflammatory Markers ◽  
Review Of The Literature

Lack of Association Between STAT4 Gene Polymorphism and Biopsy-proven Giant Cell Arteritis

2009 ◽  
Vol 36 (5) ◽  
pp. 1021-1025 ◽  
Author(s):  
ROGELIO PALOMINO-MORALES ◽  
TOMAS R. VAZQUEZ-RODRIGUEZ ◽  
INMACULADA C. MORADO ◽  
SANTOS CASTAÑEDA ◽  
NORBERTO ORTEGO-CENTENO ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Giant Cell Arteritis ◽  
Giant Cell ◽  
Statistical Significance ◽  
Clinical Manifestations ◽  
Clinical Expression ◽  
Potential Implication ◽  
Genotype Frequencies ◽  
Ischemic Complications

Objective.To investigate the potential implication of the STAT4 gene polymorphism rs7574865 in the predisposition to or the clinical expression of giant cell arteritis (GCA).Methods.A total of 212 patients diagnosed with biopsy-proven GCA were studied. DNA from patients and controls matched by age, sex, and ethnicity was obtained from peripheral blood. Samples were genotyped for STAT4 rs7574865 polymorphism.Results.No statistically significant differences in the allele frequencies for the STAT4 rs7574865 polymorphism were observed between patients and controls. Although we observed an increased frequency of the T/T genotype in GCA patients (6.0%) compared to healthy controls (3.9%), this difference did not achieve statistical significance (OR 1.57, 95% CI 0.72–3.41). No statistically significant differences in allele or genotype frequencies were observed when patients were stratified according to the presence of typical disease features such as polymyalgia rheumatica, severe ischemic manifestations, and visual ischemic complications in the setting of this vasculitis.Conclusion.Our results do not support a major role of the STAT4 rs7574865 gene polymorphism in susceptibility to or clinical manifestations of GCA.

Poster 326 Giant Cell Arteritis with Acute Hemiparesis: A Case Report

PM&R ◽  
2014 ◽  
Vol 6 (9) ◽  
pp. S298
Author(s):  
Behdad Hamidi Ravari ◽  
Ravi Mirpuri ◽  
Sujin Lee ◽  
Naveed Natanzi ◽  
Michelle Thai
Keyword(s):  
Case Report ◽  
Giant Cell Arteritis ◽  
Giant Cell
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