scholarly journals Spindle Cell Variant of Embryonal Rhabdomyosarcoma: A Rare Entity with Diagnostic Challenges

Author(s):  
Puneet Kaur
2019 ◽  
Vol 12 (2) ◽  
pp. 177
Author(s):  
AdityaPratap Singh ◽  
ArunKumar Gupta ◽  
Arpita Jindal ◽  
Kalpana Mangal

1997 ◽  
Vol 116 (4) ◽  
pp. 529-532 ◽  
Author(s):  
D DON ◽  
A NEWMAN ◽  
Y FU

2012 ◽  
Vol 7 (4) ◽  
pp. 63-66
Author(s):  
MT Khadim ◽  
A Asif ◽  
Z Ali ◽  
S Jamal ◽  
Rizwan

Spindle cell variant of Rhabdomyosarcoma is a rare malignant tumor in adults but even more so in tongue. We report a case of a 17 year old boy who presented with a polypoidal swelling on the tip of the tongue. The mass was excised and the specimen was sent to the Histopathology Department of Armed Forces Institute of Pathology for Histomorphological diagnosis. The histological evaluation showed a malignant spindle cell tumor. On the basis of morphological features and immunohistochemistry findings a final diagnosis of Rhabdomyosarcoma, Spindle cell variant was made. Journal of College of Medical Sciences-Nepal,2011,Vol-7,No-4, 63-66 DOI: http://dx.doi.org/10.3126/jcmsn.v7i4.6814


2019 ◽  
Vol 15 ◽  
pp. 105-109
Author(s):  
Nurjati Chairani Siregar ◽  
Ali Abdullah ◽  
Achmad Fauzi Kamal

2014 ◽  
Vol 139 (12) ◽  
pp. 1565-1567 ◽  
Author(s):  
Meghan P. Riley ◽  
Dipti M. Karamchandani

Hibernoma arising in the breast is rare and may present as an asymptomatic mass or may be detected by screening mammography. Four histologic types have been identified: typical, myxoid variant, spindle cell variant, and the lipoma-like variant. The most common “typical variant” is composed of pale to eosinophilic multivacuolated cells with interspersed univacuolar cells. Hibernomas are universally benign and are not known to recur or have an aggressive behavior, even in incompletely excised lesions. Hence, their clinical importance lies in distinguishing them from other benign and malignant breast neoplasms as well as inflammatory conditions that come into the histologic or radiologic differential. This review discusses the clinical features, radiologic and histopathologic characteristics, ancillary studies, suggested pathogenesis, differential diagnosis, and treatment of and prognosis for these uncommon lesions.


2019 ◽  
Vol 24 (3) ◽  
pp. 219
Author(s):  
AdityaPratap Singh ◽  
Kalpana Mangal ◽  
Ramesh Tanger ◽  
ArunKumar Gupta ◽  
Maryem Ansari ◽  
...  

Author(s):  
ROSEANE CARVALHO VASCONCELOS ◽  
LUCIANA ELOISA DA SILVA CASTRO NÓBREGA ◽  
VIVIANE ALVES DE OLIVEIRA MAIA ◽  
EDILMAR DE MOURA SANTOS ◽  
VICTOR DINIZ BORBOREMA DOS SANTOS ◽  
...  

2003 ◽  
Vol 127 (3) ◽  
pp. 352-355
Author(s):  
Richard J. Zarbo ◽  
Mark T. Marunick ◽  
Robert Johns

Abstract In this report, we document the histologic and clinical features of a previously undefined spindle cell variant of ameloblastoma that eventually behaved in a malignant fashion during a protracted course. The predominant histologic pattern was a well-differentiated, cellular, spindled epithelial proliferation arising in the maxilla of a 14-year-old African American girl. Over 19 years, the patient experienced numerous local recurrences, metastases to distant bones after 15 years, and finally bulky local recurrence with intracranial extension resulting in death. This ameloblastic malignancy histologically simulates a low-grade true sarcoma or an ameloblastic sarcoma, but differs in that the extensive spindle cell proliferation is epithelial, characterized by strong cytokeratin immunoreactivity and negative vimentin staining.


1970 ◽  
Vol 1 (1) ◽  
pp. 45-48 ◽  
Author(s):  
A Ghosh ◽  
N Nepal ◽  
MD Gharti ◽  
S Basnet ◽  
M Baxi ◽  
...  

Background: Thyroid cancer is fairly common. The worldwide annual incidence ranges from 0.5 to 10 cases per 100,000 people. Anaplastic thyroid carcinoma, comprising less than 10% of all thyroid carcinomas, remains one of the most virulent of all cancers in humans with a 10 year survival rate of only 0.1 %. In the present study we looked into the clinical, cytological and histological spectrum of anaplastic carcinoma and compared our experience with recent literature. Materials and Methods: This was a hospital based retrospective study from January 2000 to November 2010. Clinical, cytological and histopathological data of all the diagnosed anaplastic thyroid carcinoma cases were reviewed and analyzed. Results: Of the 59 thyroid malignancies diagnosed in the same period, 7 cases were anaplastic carcinoma. The mean age was 63 years and was predominantly found in females. All of the cases presented with a neck mass that lasted for a mean of 5.7 months. The mean tumor size was 14.9 cm and the most common sub-type was the spindle cell type. Atypical mitosis of more than 5 per high power field and necrosis was noted in all cases. Conclusion: Due to the markedly aggressive nature of this tumor and its association with areas of endemic thyroid disease, early diagnosis and aggressive therapy is essential, especially in the Himalayan and Sub-Himalayan belt. Keywords: Anaplastic carcinoma; Thyroid carcinoma; Spindle cell variant DOI: 10.3126/jpn.v1i1.4451 Journal of Pathology of Nepal (2011) Vol.1, 45-48


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