scholarly journals Mammary Hibernoma: A Rare Entity

2014 ◽  
Vol 139 (12) ◽  
pp. 1565-1567 ◽  
Author(s):  
Meghan P. Riley ◽  
Dipti M. Karamchandani
Keyword(s):  
Differential Diagnosis ◽  
Spindle Cell ◽  
Clinical Importance ◽  
Screening Mammography ◽  
Rare Entity ◽  
Inflammatory Conditions ◽  
Malignant Breast ◽  
Cell Variant ◽  
Histologic Types ◽  
Ancillary Studies

Hibernoma arising in the breast is rare and may present as an asymptomatic mass or may be detected by screening mammography. Four histologic types have been identified: typical, myxoid variant, spindle cell variant, and the lipoma-like variant. The most common “typical variant” is composed of pale to eosinophilic multivacuolated cells with interspersed univacuolar cells. Hibernomas are universally benign and are not known to recur or have an aggressive behavior, even in incompletely excised lesions. Hence, their clinical importance lies in distinguishing them from other benign and malignant breast neoplasms as well as inflammatory conditions that come into the histologic or radiologic differential. This review discusses the clinical features, radiologic and histopathologic characteristics, ancillary studies, suggested pathogenesis, differential diagnosis, and treatment of and prognosis for these uncommon lesions.

scholarly journals Gastric Angiolipoma: A Rare Entity

2017 ◽  
Vol 141 (6) ◽  
pp. 862-866 ◽  
Author(s):  
Yong-Jun Liu ◽  
Dipti M. Karamchandani
Keyword(s):  
Differential Diagnosis ◽  
English Language ◽  
Benign Tumor ◽  
Clinical Symptoms ◽  
Subcutaneous Tissue ◽  
Correct Diagnosis ◽  
Gastric Neoplasms ◽  
Rare Entity ◽  
Accurate Preoperative Diagnosis ◽  
Ancillary Studies

Angiolipoma is a benign tumor composed of adipose tissue and proliferating blood vessels that is commonly found in the subcutaneous tissue of the trunk and extremities. Gastric angiolipoma is a rare entity, and to the best of our knowledge, only 4 cases have been reported in the English-language literature thus far. These tumors may present as gastrointestinal bleeding and anemia or with obstructive symptoms. Accurate preoperative diagnosis is challenging because of nonspecific clinical symptoms and lack of specific findings on imaging studies. The correct diagnosis is usually made by histopathologic examination. The clinical significance lies in being aware of this rare entity in the stomach and distinguishing it from other benign and malignant gastric neoplasms that may be in the differential diagnosis. We herein discuss the clinical presentation, radiologic and histopathologic features, ancillary studies, differential diagnosis, and treatment and prognosis of this rare entity.

scholarly journals Cellular Spindled Histiocytic Pseudotumor: A Benign Mimic of Spindle Cell Neoplasia of the Breast

2019 ◽  
Vol 143 (12) ◽  
pp. 1497-1503
Author(s):  
Ellen G. East ◽  
Cody S. Carter ◽  
Andrew P. Sciallis
Keyword(s):  
Differential Diagnosis ◽  
Spindle Cell ◽  
Data Sources ◽  
Fat Necrosis ◽  
Ancillary Studies

Context.— Cellular spindled histiocytic pseudotumor (CSHPT) is an exuberant, dense histiocytic proliferation seen in the setting of mammary fat necrosis. CSHPT has a broad histologic differential diagnosis, including benign, malignant, and inflammatory etiologies. Objectives.— To highlight the most important histologic and immunohistochemical findings of CSHPT and provide comparisons to entities within the broad differential diagnosis. Data Sources.— Recently published literature regarding CSHPT and other diagnostic considerations. Conclusions.— CSHPT is a benign histiocytic proliferation with a broad differential diagnosis, for which comprehensive ancillary studies may be required to exclude malignant and infectious entities.

Benign spindle cell lesions of the breast: a diagnostic approach to solitary fibrous tumour, nodular pseudoangiomatous stromal hyperplasia and nodular fasciitis

2019 ◽  
Vol 72 (6) ◽  
pp. 438-442 ◽  
Author(s):  
Julia R Naso ◽  
Connie G Chiu ◽  
Michelle E Goecke ◽  
Debra Chang ◽  
Carolyn J Shiau
Keyword(s):  
Differential Diagnosis ◽  
Clinical Management ◽  
Core Biopsy ◽  
Spindle Cell ◽  
Solitary Fibrous Tumour ◽  
Accurate Diagnosis ◽  
Diagnostic Approach ◽  
Nodular Fasciitis ◽  
Pseudoangiomatous Stromal Hyperplasia ◽  
Ancillary Studies

Benign spindle cell lesions of the breast include neoplastic and reactive entities that are diagnostically challenging given their rarity and similar histomorphology. Accurate diagnosis on percutaneous core biopsy within this category is essential as some lesions require excision and surveillance, whereas others may be observed. We present three cases of rare benign spindle cell lesions of the breast that reflect the diversity of this group: solitary fibrous tumour, nodular pseudoangiomatous stromal hyperplasia and nodular fasciitis. Through these cases, we discuss the associated differential diagnosis and demonstrate how emerging ancillary studies can be integrated into a diagnostic approach. We highlight distinctive clinical and histopathological features and summarise recent updates to the clinical management of these lesions. An organised approach to the broad differential of spindle cell lesions is essential for appropriate diagnosis and treatment.

scholarly journals Spindle cell rhabdomyosarcoma of the tongue – A rare entity

2012 ◽  
Vol 7 (4) ◽  
pp. 63-66
Author(s):  
MT Khadim ◽  
A Asif ◽  
Z Ali ◽  
S Jamal ◽  
Rizwan
Keyword(s):  
Spindle Cell ◽  
Armed Forces ◽  
Final Diagnosis ◽  
Cell Tumor ◽  
Histological Evaluation ◽  
Rare Entity ◽  
Spindle Cell Tumor ◽  
Medical Sciences ◽  
Cell Variant ◽  
Tip Of The Tongue

Spindle cell variant of Rhabdomyosarcoma is a rare malignant tumor in adults but even more so in tongue. We report a case of a 17 year old boy who presented with a polypoidal swelling on the tip of the tongue. The mass was excised and the specimen was sent to the Histopathology Department of Armed Forces Institute of Pathology for Histomorphological diagnosis. The histological evaluation showed a malignant spindle cell tumor. On the basis of morphological features and immunohistochemistry findings a final diagnosis of Rhabdomyosarcoma, Spindle cell variant was made. Journal of College of Medical Sciences-Nepal,2011,Vol-7,No-4, 63-66 DOI: http://dx.doi.org/10.3126/jcmsn.v7i4.6814

Castleman's Disease Masquerading as Sigmoid Colon Tumor and Hodgkin Lymphoma

Swiss Surgery ◽  
2002 ◽  
Vol 8 (1) ◽  
pp. 7-10 ◽  
Author(s):  
Altinli ◽  
Pekmezci ◽  
Balkan ◽  
Somay ◽  
M. Akif Buyukbese ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Hodgkin Lymphoma ◽  
Sigmoid Colon ◽  
Castleman’S Disease ◽  
Malignant Potential ◽  
Colon Tumor ◽  
Rare Entity ◽  
Castleman's Disease ◽  
Mediastinal Lymph Nodes ◽  
Histologic Types

Castleman's disease is a benign lymphoid neoplasm first reported as hyperplasia of mediastinal lymph nodes. Some authors referred to the lesions as isolated tumors, described as a variant of Hodgkin's disease with a possibility of a malignant potential and others proposed that the lymphoid masses were of a hamartomatous nature. Three histologic variants and two clinical types of the disease have been described. The disease may occur in almost any area in which lymph nodes are normally found. The most common locations are thorax (63%), abdomen (11%) and axilla (4%). We report two separate histologic types of Castleman's disease which were rare in the literature, mimicking sigmoid colon tumor and Hodgkin lymphoma. The diagnostic and therapeutic aspects of this rare entity is discussed.

scholarly journals Dysgenetic Polycystic Disease of Minor Salivary Gland: A Rare Case Report and Review of the Literature

2017 ◽  
Vol 2017 ◽  
pp. 1-5
Author(s):  
N. Srikant ◽  
Shweta Yellapurkar ◽  
Karen Boaz ◽  
Mohan Baliga ◽  
Nidhi Manaktala ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Salivary Gland ◽  
Case Report ◽  
Rare Case ◽  
Minor Salivary Gland ◽  
Rare Entity ◽  
Review Of The Literature ◽  
Lower Lip ◽  
Polycystic Disease ◽  
Rare Case Report

Polycystic (dysgenetic) disease of the salivary glands is a rare entity that has only recently been described in the literature. The disease is more commonly seen in females and majority of the cases have presented as bilateral parotid gland swellings. This case presenting in a 21-year-old male is the first of this unusual entity involving solely the minor salivary gland on the lower lip. This case report highlights the importance for the clinician to be aware of this differential diagnosis, when treating an innocuous lesion like a mucocele.

Spindle Cell Carcinoma in a Young Man: A Case Report of a Rare Entity

2015 ◽  
Vol 120 (2) ◽  
pp. e27
Author(s):  
ROSEANE CARVALHO VASCONCELOS ◽  
LUCIANA ELOISA DA SILVA CASTRO NÓBREGA ◽  
VIVIANE ALVES DE OLIVEIRA MAIA ◽  
EDILMAR DE MOURA SANTOS ◽  
VICTOR DINIZ BORBOREMA DOS SANTOS ◽  
...  
Keyword(s):  
Case Report ◽  
Cell Carcinoma ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
Rare Entity

Malignant Ameloblastoma, Spindle Cell Variant

2003 ◽  
Vol 127 (3) ◽  
pp. 352-355
Author(s):  
Richard J. Zarbo ◽  
Mark T. Marunick ◽  
Robert Johns
Keyword(s):  
Spindle Cell ◽  
Intracranial Extension ◽  
Low Grade ◽  
Epithelial Proliferation ◽  
American Girl ◽  
Spindle Cell Proliferation ◽  
Histologic Pattern ◽  
Cell Variant ◽  
Well Differentiated ◽  
African American Girl

Abstract In this report, we document the histologic and clinical features of a previously undefined spindle cell variant of ameloblastoma that eventually behaved in a malignant fashion during a protracted course. The predominant histologic pattern was a well-differentiated, cellular, spindled epithelial proliferation arising in the maxilla of a 14-year-old African American girl. Over 19 years, the patient experienced numerous local recurrences, metastases to distant bones after 15 years, and finally bulky local recurrence with intracranial extension resulting in death. This ameloblastic malignancy histologically simulates a low-grade true sarcoma or an ameloblastic sarcoma, but differs in that the extensive spindle cell proliferation is epithelial, characterized by strong cytokeratin immunoreactivity and negative vimentin staining.

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