scholarly journals Neonatal Hyperthyroidism with Fulminant Liver Failure: A Case Report

Author(s):  
Mohammed Hasosah
1997 ◽  
Vol 112 (5) ◽  
pp. 1707-1709 ◽  
Author(s):  
B Macfarlane ◽  
S Davies ◽  
K Mannan ◽  
R Sarsam ◽  
D Pariente ◽  
...  

2020 ◽  
Vol 115 (1) ◽  
pp. S1312-S1312
Author(s):  
Nirali Sheth ◽  
Jonathan Vincent M. Reyes ◽  
Melanie Burgos ◽  
Tasur Seen ◽  
Fahad Malik ◽  
...  

2018 ◽  
Vol 113 (Supplement) ◽  
pp. S1322
Author(s):  
Sachit Sharma ◽  
Ashu Acharya ◽  
Alok Uprety ◽  
Abhushan Poudyal ◽  
Sadikshya Sharma

2020 ◽  
pp. 1-5
Author(s):  
Olivier Zerbib ◽  
Benjamin Zribi ◽  
David Dahan ◽  
Eviatar Nesher ◽  
Jonathan Cohen ◽  
...  

Objective: To describe the experience with a multimodal therapeutic approach in a patient who developed toxic liver syndrome and fulminant hepatic failure following orthotopic liver transplantation (OLT) as a result of occlusion of the portal vein. Setting: Department of Intensive Care. Patient: A patient with liver cirrhosis secondary to autoimmune hepatitis and primary biliary cirrhosis who underwent orthotopic liver transplantation (OLT). Interventions: Transplant hepatectomy, plasmapheresis and retransplantation. Case Report: A 39-year-old man underwent an elective OLT. A routine postoperative doppler ultrasound examination a few hours after surgery revealed portal vein thrombosis. Attempts at recanalization failed, and the patient developed acute fulminant liver failure, which remained resistant to supportive therapy. A transplant hepatectomy was performed 9 hours later and plasmapheresis started. Following a 10-hour anhepatic period, the patient received a second liver, from an ABO-incompatible donor. The patient underwent column plasmapheresis and subsequent splenectomy to remove anti-B antibody to preserve the incompatible transplanted liver from immunogenic complications. The patient spent a total of 21 days in the Intensive Care Unit (ICU) before being discharged to a step-down ward. Conclusion: Our experience suggests that multimodal therapy, including transplant hepatectomy, plasmapheresis and retransplantation of an even non-ABO compatible liver may result in the successful outcome in patients with acute fulminant liver failure complicating OLT.


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