scholarly journals DETERMINATION OF ANDROGRAPHOLIDE IN ANDROGRAPHIS PANICULATA EXTRACTS WITH AND WITHOUT HUMAN SERUM BY HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY

2014 ◽  
Vol 4 (12) ◽  
pp. 41-45
Author(s):  
Mohan Manvitha
Keyword(s):  
Thin Layer ◽  
Human Serum ◽  
Thin Layer Chromatography ◽  
High Performance ◽  
Andrographis Paniculata ◽  
Layer Chromatography

Quantitative determination of paroxetine in human serum by high-performance thin-layer chromatography

2015 ◽  
Vol 28 (3) ◽  
pp. 229-233 ◽  
Author(s):  
Sigrid Mennickent ◽  
Cristina Cifuentes ◽  
Mario Vega ◽  
Gisela Ríos ◽  
Marta de Diego
Keyword(s):  
Thin Layer ◽  
Quantitative Determination ◽  
Human Serum ◽  
Thin Layer Chromatography ◽  
High Performance ◽  
Layer Chromatography

scholarly journals Assay of Tinidazole in Human Serum by High-Performance Thin-Layer Chromatography—Comparison with High-Performance Liquid Chromatography

1999 ◽  
Vol 82 (2) ◽  
pp. 244-247 ◽  
Author(s):  
M H Guermouche ◽  
D Habel ◽  
S Guermouche
Keyword(s):  
High Performance Liquid Chromatography ◽  
Thin Layer ◽  
Human Serum ◽  
Thin Layer Chromatography ◽  
Mobile Phase ◽  
High Performance ◽  
Reversed Phase ◽  
Reversed Phase Hplc ◽  
Layer Chromatography

Abstract Determination of tinidazole in human serum by high-performance thin-layer chromatography (HPTLC) is presented. It includes use of 10 × 10 cm plates coated with silica gel 60 and chloroform-acetonitrile-acetic acid (60 + 40 + 2) as mobile phase. Quantitation was performed by densitometry at 320 nm. The linearity (1-10 ng), precision (6%), reproducibility (5%), recovery (96%), and detection limit (1 mg/L) of tinidazole determination by HPTLC were comparable with corresponding method parameters by reversed-phase HPLC. A satisfactory correlation was found between the 2 analytical methods. The procedure was used to quantitate tinidazole in patient sera.

Quantitative determination of fluoxetine in human serum by high performance thin layer chromatography

2010 ◽  
Vol 33 (14) ◽  
pp. 2206-2210 ◽  
Author(s):  
Sigrid Mennickent ◽  
Ricardo Fierro ◽  
Mario Vega ◽  
Marta De Diego ◽  
C. Gloria Godoy
Keyword(s):  
Thin Layer ◽  
Quantitative Determination ◽  
Human Serum ◽  
Thin Layer Chromatography ◽  
High Performance ◽  
Layer Chromatography

Determination of free duloxetine in human serum by high-performance thin-layer chromatography

2013 ◽  
Vol 26 (4) ◽  
pp. 354-357 ◽  
Author(s):  
Prathikantam Pushpalatha ◽  
Rajendra Sarin ◽  
Mohd Idris ◽  
Mesineni Rao ◽  
Tulsidas Baggi ◽  
...  
Keyword(s):  
Thin Layer ◽  
Human Serum ◽  
Thin Layer Chromatography ◽  
High Performance ◽  
Layer Chromatography

Recent Applications of High Performance Thin Layer Chromatography and Derivative Spectrophotometry in Pharmaceutical Analysis

2020 ◽  
Vol 16 (6) ◽  
pp. 671-689
Author(s):  
Marcin Gackowski ◽  
Marcin Koba ◽  
Katarzyna Mądra-Gackowska ◽  
Piotr Kośliński ◽  
Stefan Kruszewski
Keyword(s):  
Thin Layer ◽  
Thin Layer Chromatography ◽  
Pharmaceutical Analysis ◽  
High Performance ◽  
Degradation Products ◽  
Derivative Spectrophotometry ◽  
Accuracy And Precision ◽  
Post Marketing ◽  
Layer Chromatography

At present, no one can imagine drug development, marketing and post-marketing without rigorous quality control at each stage. Only modern, selective, accurate and precise analytical methods for determination of active compounds, their degradation products and stability studies are able to assure the appropriate amount and purity of drugs administered every day to millions of patients all over the world. For routine control of drugs simple, economic, rapid and reliable methods are desirable. The major focus of current scrutiny is placed on high-performance thin layer chromatography and derivative spectrophotometry methods, which fulfill routine drug estimation’s expectations [1-4]. The present paper reveals state-of-the-art and possible applications of those methods in pharmaceutical analysis between 2010 and 2018. The review shows advantages of high-performance thin layer chromatography and derivative spectrophotometry, including accuracy and precision comparable to more expensive and time-consuming methods as well as additional fields of possible applications, which contribute to resolving many analytical problems in everyday laboratory practice.

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