Chronic lymphatic leukemia is a lymphoproliferative disease typical in adult age. It is characterized by a proliferation in the peripheral blood and bone marrow of mature lymphocytes progressively permeating the lymphonodes, spleen, liver and more rarely the uro-genital apparatus. This case report concerns a man suffering from C.L.L. since 1972, treated with medical therapy; from 1991 onwards the patient reported a pain in the right lumbar area. Radiological examinations showed a subcapsular corpuscular mass 3.3 cm thick with no change in the kidney parenchyma. Examination of the blood showed hyperleucocytosis. The patient underwent right nephrectomy after biopsy; the histological examination showed leukemic infiltration compatible with C.L.L. The patient then underwent therapy with Fludarabine and is at present in good condition.
Aggressive cutaneous vasculitis in a patient with chronic lymphatic leukemia following granulocyte colony stimulating factor injection: a case report