Thrombocytosis Associated with Lower Respiratory Tract Infection in Pediatric Population: A Two-year Retrospective Study

2021 ◽  
pp. 44-49
Author(s):  
Priyanka Kiyawat ◽  
Ashok Panchonia ◽  
Sonal Meshram ◽  
Shailendra Singh Thakur
Keyword(s):  
Retrospective Study ◽  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Lower Respiratory Tract Infection ◽  
Lower Respiratory Tract ◽  
Pediatric Population

scholarly journals A Review of Microbiologic Isolates of Adults with Lower Respiratory Tract Infection

2019 ◽  
pp. 1-8
Author(s):  
Yunusa, Thairu ◽  
Akor, Alexander Agada
Keyword(s):  
Staphylococcus Aureus ◽  
Retrospective Study ◽  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Lower Respiratory Tract Infection ◽  
Lower Respiratory Tract ◽  
Laboratory Unit ◽  
Antibiotics Susceptibility ◽  
And Staphylococcus Aureus

Aims: This study was designed to determine the isolates from microbial cultures and the antibiotics susceptibility pattern of adults with lower respiratory tract infection. Study Design: A retrospective study. Place and Duration of Study: This study was carried out at the Pulmonology units of Medicine department and Microbiology research laboratory unit, Microbiology and Parasitology department, University of Abuja Teaching Hospital (UATH) Gwagwalada, Federal Capital Territory (F.C.T) from August 2015 to September 2018 (Thirty-six months). Methodology: This was a retrospective study. patients with LRTI who met the inclusion criteria were reviewed. The data were extracted from patients’ case notes using well-structured tools. The quality of clinical and laboratory work up were verified by the contribution of specialist Pulmonologist and Microbiologist in the management of patients.  Results: A total of one hundred and ninety-eight sample were reviewed of which fifty-seven percent (112) were males and the mean age of the study populations was 37± 13.8 years. From the positive cultures 86.9% were bacteremia and 4.0% were fungaemia. Streptococcus pneumoniae (30.3%) was the most predominant bacteria recovered from the sputum specimens; closely followed by Klebsiella pneumoniea and Staphylococcus aureus. imipenem and ofloxacin had good susceptibility activity and bacteria eradication rate with susceptibility rate of 92.8% and 92.5% respectively. Erythromycin, Augmentin and ceftriaxone had susceptibility of 66.2%, 89.4% and 90.0% respectively. Conclusion: Streptococcus pneumonia, Klebsiella pneumoniea and Staphylococcus aureus are the most common bacteria isolated from sputum of patient who presented with LRTI. Quinolone (ofloxacin) and imipinem are the most sensitive antibiotics and should be considered in initiation of empiric antibiotic treatment.

scholarly journals Airway Malformations and Bronchiectasis: A Pediatric Study

2019 ◽  
Vol 99 (1) ◽  
pp. 44-46
Author(s):  
Amrita Dosanjh
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Lower Respiratory Tract Infection ◽  
Lower Respiratory Tract ◽  
Pediatric Population ◽  
Upper Airway ◽  
Number Of Patients ◽  
Pediatric Study ◽  
Airway Anomalies

Congenital airway malformations are most often identified in early childhood. The development of bronchiectasis in association with malformations of the lower airway has been described, particularly among adult patients. The coexistence in a pediatric population of these conditions is not well described. This study was conducted to identify whether younger patients with airway malformations commonly develop bronchiectasis. International Classification of Diseases, Ninth revision (ICD-9 codes) were defined for airway anomalies and bronchiectasis. The electronic medical records system of a children’s hospital was then searched for the number of patients with upper airway anomalies with or without bronchiectasis. The airway database was then cross referenced with the ICD codes for bronchiectasis to identify patients with both conditions. There were 844 patients with airway anomalies and 117 with bronchiectasis in the electronic system during the time period of August 1, 2009 to September 30, 2014. There was only 3 patients identified with both bronchiectasis and airway anomalies. The coexistence of bronchiectasis is low among the pediatric population with upper airway anomalies studied. This would suggest that the children with airway anomalies have been treated with strategies that are effective in the prevention of recurrent lower respiratory tract infection. Further study may be done to define the effectiveness of various strategies in preventing aspiration and lower respiratory tract infection. In addition, this methodologic technique utilizing database integrative platforms is useful in the identification of patients for further study and to identify the coexistence of pediatric conditions.

scholarly journals COPD-Lower Respiratory Tract Infection Visual Analogue Score (c-LRTI-VAS) validation in stable and exacerbated patients with COPD

2021 ◽  
Vol 8 (1) ◽  
pp. e000761
Author(s):  
Hendrik Johannes Prins ◽  
Ruud Duijkers ◽  
Johannes M A Daniels ◽  
Thys van der Molen ◽  
Tjip S van der Werf ◽  
...  
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Lower Respiratory Tract Infection ◽  
Lower Respiratory Tract ◽  
Visual Analogue Score ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Significant Difference ◽  
Related Quality

BackgroundWe developed the chronic obstructive pulmonary disease (COPD)-Lower Respiratory Tract Infection-Visual Analogue Score (c-LRTI-VAS) in order to easily quantify symptoms during exacerbations in patients with COPD. This study aimed to validate this score.MethodsIn our study, patients with stable COPD as well as those with an acute exacerbations of COPD (AECOPD) were included. The results of c-LRTI-VAS were compared with other markers of disease activity (lung function parameters, oxygen saturation and two health related quality of life questionnaires (St Georges Respiratory Questionnaire (SGRQ) and Clinical COPD Questionnaire (CCQ)) and validity, reliability and responsiveness were assessed.ResultsEighty-eight patients with clinically stable COPD and 102 patients who had an AECOPD completed the c-LRTI-VAS questionnaire. When testing on two separate occasions for repeatability, no statistically significant difference between total scores was found 0.143 (SD 5.42) (p=0.826). Internal consistency was high across items (Cronbach’s apha 0.755). Correlation with SGRQ and CCQ total scores was moderate to high. After treatment for hospitalised AECOPD, the mean c-LRTI-VAS total score improved 8.14 points (SD 9.13; p≤0.001).Conclusionsc-LRTI-VAS showed proper validity, responsiveness to change and moderate to high correlation with other questionnaires. It, therefore, appears a reliable tool for symptom measurement during AECOPD.Trial registration numberNCT01232140.

Effect of acute lower respiratory tract infection on pulmonary artery pressure in children with post-tricuspid left-to-right shunt

2021 ◽  
pp. 1-5
Author(s):  
Sakshi Sachdeva ◽  
Shyam S. Kothari ◽  
Saurabh K. Gupta ◽  
Sivasubramanian Ramakrishnan ◽  
Anita Saxena
Keyword(s):  
Tract Infection ◽  
Pulmonary Artery ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Lower Respiratory Tract Infection ◽  
Pulmonary Artery Pressure ◽  
Lower Respiratory Tract ◽  
Systolic Pressure ◽  
Pulmonary Artery Systolic Pressure ◽  
Artery Pressure

Abstract We sought to examine the influence of clinically severe lower respiratory tract infection on pulmonary artery pressure in children having CHD with post-tricuspid left-to-right shunt, as it may have physiological and clinical implications. In a prospective single-centre observational study, 45 children with post-tricuspid left-to-right shunt and clinically severe lower respiratory tract infection were evaluated during the illness and 2 weeks after its resolution. Pulmonary artery systolic pressure was estimated non-invasively using shunt gradient by echocardiography and systolic blood pressure measured non-invasively. Median pulmonary artery systolic pressure during lower respiratory tract infection was only mildly (although statistically significantly) elevated during lower respiratory tract infection [60 (42–74) versus 53 (40–73) mmHg, (p < 0.0001)]. However, clinically significant change in pulmonary artery systolic pressure defined as the increase of >10 mmHg was present in only 9 (20%) patients. In the absence of hypoxia or acidosis, only a small minority (9%, n = 4) showed significant pulmonary artery systolic pressure rise >10 mmHg. In the absence of hypoxia or acidosis, severe lower respiratory tract infection in patients with acyanotic CHD results in only mild elevation of pulmonary artery systolic pressure in most of the patients.

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