scholarly journals Frequency of asymptomatic stenotic carotid artery disease in patients with lower extremity peripheral arterial disease

2019 ◽  
Vol 28 (2) ◽  
pp. 73-77
Author(s):  
Yusuf Velioğlu
Keyword(s):  
Carotid Artery ◽  
Peripheral Arterial Disease ◽  
Lower Extremity ◽  
Carotid Artery Disease ◽  
Arterial Disease ◽  
Artery Disease ◽  
Peripheral Arterial

scholarly journals Carotid artery disease and stroke in patients with peripheral arterial disease. The role of inflammation

2016 ◽  
Vol 72 (1) ◽  
Author(s):  
Giusy Sirico ◽  
Lucrezia Spadera ◽  
Mario De Laurentis ◽  
Gregorio Brevetti
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Carotid Artery ◽  
Peripheral Arterial Disease ◽  
Carotid Artery Disease ◽  
Arterial Disease ◽  
Carotid Plaques ◽  
Markers Of Inflammation ◽  
Artery Disease ◽  
Peripheral Arterial

Although during the last decade there have been great advances in our knowledge of the epidemiology and pathophysiology of multi-district atherosclerotic disease, little is known about the association between peripheral arterial disease and carotid artery disease. This review was conceived to cast some light on this topic, paying special attention to inflammation which plays a pivotal role in atherosclerosis. An aspect of pathophysiologic and clinical relevance is that the coexistence of carotid disease is more frequent in peripheral arterial disease than in coronary artery disease, not only in terms of carotid stenosis, but also with respect to the presence of hypoechoic unstable plaque. These latter plaques present a large infiltration of macrophages and are associated to high levels of inflammatory markers. In particular, the greater prevalence of hypoechoic carotid plaques in peripheral arterial disease compared to patients with carotid artery disease was poorly related to classic risk factors, but showed an independent association with an increased number of leukocyte and neutrophil cells, which are reliable markers of inflammation. The greater prevalence of hypoechoic unstable carotid plaques could explain why peripheral arterial disease portends higher risk of stroke than coronary artery disease.

Study of DNA polymorphisms of the apolipoprotein AI-CIII-AIV gene cluster in patients with peripheral arterial disease

1989 ◽  
Vol 76 (2) ◽  
pp. 221-228 ◽  
Author(s):  
M. V. Monsalve ◽  
R. Young ◽  
S. A. Wiseman ◽  
S. Dhamu ◽  
J. T. Powell ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Peripheral Arterial Disease ◽  
Gene Cluster ◽  
Apolipoprotein B ◽  
Carotid Artery Disease ◽  
Arterial Disease ◽  
Dna Polymorphisms ◽  
Apolipoprotein Ai ◽  
Artery Disease ◽  
Peripheral Arterial

1. We have determined the frequency of DNA polymorphisms of the human apolipoprotein AI-CIII-AIV gene cluster, detected with XmnI, PstI, and PvuII, in a group of patients with peripheral arterial disease. 2. Of the patients, 81 had no evidence of disease in the coronary and carotid arteries, 73 had coronary artery disease but no evidence of carotid artery disease, 25 patients had carotid artery disease but no evidence of coronary artery disease, and 38 had both coronary and carotid artery disease. 3. Levels of triacylglycerol, cholesterol, apolipoprotein B and apolipoprotein AI were not significantly different between the four patient groups. 4. The frequencies of the alleles for the apolipoprotein AI-CIII-AIV polymorphisms, detected with XmnI, PstI and PvuII, did not differ significantly in the patient groups when compared with a sample of clinically well normolipidaemic individuals also from a London population. 5. All five patients with the XmnI genotype we designate X2X2 had high levels of cholesterol, apolipoprotein B and apolipoprotein AI. 6. Patients with the rare VB2 allele of the apolipoprotein CIII-AIV restriction fragment length polymorphism had lower levels of cholesterol, acylglycerol and significantly lower levels of serum apolipoprotein. 7. Our observations suggest that variation in the apolipoprotein AI-CIII-AIV gene cluster may not be contributing significantly to the development of peripheral arterial disease, but variation associated with some of the restriction fragment length polymorphisms may be involved in determining levels of cholesterol- and apolipoprotein-B-containing lipoproteins.

Is peripheral arterial disease associated with carotid artery disease in Egyptians? A pilot study

2016 ◽  
Vol 53 (1) ◽  
pp. 12
Author(s):  
Ahmed Sayed ◽  
SandraM Ahmed ◽  
AhmedM Abdelalim ◽  
Martin Nagah ◽  
Hussein Khairy
Keyword(s):  
Pilot Study ◽  
Carotid Artery ◽  
Peripheral Arterial Disease ◽  
Carotid Artery Disease ◽  
Arterial Disease ◽  
Artery Disease ◽  
Peripheral Arterial

ASSESSMENT OF THE PREVALENCE AND SEVERITY OF CAROTID ARTERY DISEASE IN PATIENTS WITH PERIPHERAL ARTERIAL DISEASE

2005 ◽  
Vol 26 (S 1) ◽  
Author(s):  
A Drelich-Zbroja ◽  
M Elfurah ◽  
T Jargiello ◽  
M Rzeszowska-Sieczka ◽  
M Szczerbo-Trojanowska
Keyword(s):  
Carotid Artery ◽  
Peripheral Arterial Disease ◽  
Carotid Artery Disease ◽  
Arterial Disease ◽  
Artery Disease ◽  
Peripheral Arterial

Screening for Peripheral Arterial Disease and Carotid Artery Disease in Patients With Abdominal Aortic Aneurysm

Angiology ◽  
2015 ◽  
Vol 67 (4) ◽  
pp. 346-349 ◽  
Author(s):  
Cleona Gray ◽  
Patrick Goodman ◽  
Paul Cullen ◽  
Stephen A. Badger ◽  
Kevin O'Malley ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Carotid Artery ◽  
Peripheral Arterial Disease ◽  
Carotid Artery Disease ◽  
Arterial Disease ◽  
Abdominal Aortic ◽  
Artery Disease ◽  
Peripheral Arterial

scholarly journals Epidemiological aspects of carotid disease

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Savetka Paljoskovska-Jordanova
Keyword(s):  
Risk Factors ◽  
Carotid Artery ◽  
Peripheral Arterial Disease ◽  
Carotid Stenosis ◽  
Carotid Artery Disease ◽  
Arterial Disease ◽  
Carotid Disease ◽  
Artery Disease ◽  
Peripheral Arterial ◽  
The University

Carotid artery disease most commonly manifests as atherosclerotic carotid artery disease, which can lead to an ischemic stroke. Our aim was to present the epidemiological aspects of carotid disease and to demonstrate the association of risk factors with carotid disease. For that purpose, we prospectively followed 1031 patients at the University Clinic for Cardiology in Skopje, who were examined for carotid stenosis and its correlation with risk factors such as hypertension, smoking, hyperlipidemia, diabetes, obesity and peripheral arterial disease. Results: Carotid stenosis was correlated with arterial hypertension, hyperlipidemia, diabetes mellitus, smoking, and peripheral arterial disease. Conclusions: Our study found that conventional risk factors such as hypertension, diabetes, smoking, and dyslipidemia were independently associated with significant carotid artery disease and peripheral arterial disease.

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