cell surgery
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Nano Letters ◽  
2021 ◽  
Author(s):  
Xiaoting Zhao ◽  
Yang Shi ◽  
Ting Pan ◽  
Dengyun Lu ◽  
Jianyun Xiong ◽  
...  

Author(s):  
Vitaly A. Orlov ◽  
◽  
Roman Yu. Rudenko ◽  
Vladimir S. Prokopenko ◽  
Irina N. Orlova ◽  
...  

Collective modes of the gyrotropic motion of a magnetic vortex core in ordered arrays of triangular and square ferromagnetic film nanodots have been theoretically investigated. The dispersion relations have been derived. The dipole–dipole interaction of the magnetic moments of the magnetic vortex cores of elements has been taken into account in the approximation of a small shift from the equilibrium position. It is shown that the effective rigidity of the magnetic subsystem of triangular elements is noticeably higher than that of the subsystem of square elements of the same linear sizes. The potential application of the polygonal film nanodisks as nanoscalpels for noninvasive tumor cell surgery is discussed


2021 ◽  
Author(s):  
Paolo Giuseppe Limoli ◽  
Celeste Limoli ◽  
Enzo Maria Vingolo ◽  
Federica Franzone ◽  
Marcella Nebbioso

Abstract Background Glaucomatous optic neuropathy (GON) is an anatomofunctional impairment of the optic nerve triggered by glaucoma. Recently, growth factors (GF) have been shown to produce retinal neuroenhancement. The suprachoroidal autograft of mesenchymal stem cells (MSC) by Limoli Retinal Restoration Technique (LRRT) has proven to achieve retinal neuroenhancement by producing GF directly into the choroidal space. This retrospectively registered clinical study investigated the visual function changes in patients with GON treated with LRRT. Methods: Twenty-five patients (35 eyes) with GON in progressive disease conditions were included in the study. Each patient underwent a comprehensive ocular examination, including analysis of Best Corrected Visual Acuity (BCVA) for far and near visus, sensitivity by Maia microperimetry, and the study of the spectral domain-optical coherence tomography (SD-OCT). The patients were divided into two groups: a control group, consisting of 21 eyes (average age 72.2 years, range 50–83) and an LRRT group, consisting of 14 eyes (average age 67.4, range 50–84). Results: After 6 months the BCVA, close-up visus, and microperimetric sensitivity significantly improved in the LRRT-treated group (p < 0.05), whereas the mean increases were not statistically significant in controls (p > 0.5). Conclusions: Patients with GON treated with LRRT showed a significant increase of visual performance (VP) both in BCVA and sensitivity and an improvement of residual close-up visus, in the comparison between the LRRT results and the control group. Further studies will be needed to establish the actual significance of the reported findings.


2021 ◽  
Author(s):  
Jeffrey N. Weiss
Keyword(s):  

2021 ◽  
Author(s):  
Jeffrey N. Weiss
Keyword(s):  

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