Peri-Operative Stress-Related Cardiomyopathy Following Paediatric Liver Transplant– A Case Series

Perioperative stress-related cardiomyopathy has been extensively described in adults undergoing liver transplantation to be associated with adverse outcomes. Reports of stress-related cardiomyopathy among children is scarce and is usually associated with better clinical outcomes compared to adults. We describe 3 instances of pediatric liver transplantation who developed stress-related cardiomyopathy during the perioperative period and had adverse clinical outcomes. Keywords: Liver Transplantation; Stress-related cardiomyopathy; Heart failure.

Review: Hepatoprotector Compounds in Plant Extracts

Many plants have been reported to possess hepatoprotective activity. The mechanism has not yet been revealed, but it was predicted due to the antioxidants that could prevent the formation of free radicals produced by hepatotoxins. Of the 30 plants studied, Crocus sativus gave the largest hepatoprotector activity at a dose of 20 mg / kg, followed by Uncaria gambier Roxb. with a dose of 30 mg / kg and Melastoma malabathricum Leaf at a dose of 50 mg / kg. Keywords: Liver, CYP450, antioxidant, free radicals