piperidine derivative
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Discovery of a cinnamyl piperidine derivative as new neddylation inhibitor for gastric cancer treatment

2021 ◽  
Vol 226 ◽  
pp. 113896
Author(s):  
Bo Wang ◽  
Qiu-Hua Zhang ◽  
Xiao-Jing Li ◽  
Sai-Qi Wang ◽  
Xiao-Bing Chen ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Treatment ◽  
Piperidine Derivative ◽  
Gastric Cancer Treatment

Synthesis, structural, spectral, antidiabetic, DNA interactions and molecular docking investigations of a Piperidine derivative

2021 ◽  
pp. 131692
Author(s):  
Radhakrishnan Nandini Asha ◽  
Murugesan Sankarganesh ◽  
Nattamai Bhuvanesh ◽  
Balasingh Ravindran Durai Nayagam
Keyword(s):  
Molecular Docking ◽  
Dna Interactions ◽  
Piperidine Derivative

A case of delayed antihistamine cutaneous drug eruption and piperidine derivative cross‐ reaction

2021 ◽  
Author(s):  
Mathieu Lagassy ◽  
Marine Aroux‐Pavard ◽  
Pascal Joly ◽  
Florence Tetart ◽  
Olivia Bauvin
Keyword(s):  
Drug Eruption ◽  
Cross Reaction ◽  
Piperidine Derivative

scholarly journals New piperidine derivative DTPEP acts as dual-acting anti-breast cancer agent by targeting ERα and downregulating PI3K/Akt-PKCα leading to caspase-dependent apoptosis

2018 ◽  
Vol 51 (6) ◽  
pp. e12501 ◽  
Author(s):  
A. Arun ◽  
M.I. Ansari ◽  
P. Popli ◽  
S. Jaiswal ◽  
A.K. Mishra ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Piperidine Derivative ◽  
Cancer Agent

Local Anesthetic Activity of a Promising Piperidine Derivative (LAS-54) in Combination with Epinephrine

2016 ◽  
Vol 50 (9) ◽  
pp. 600-602 ◽  
Author(s):  
G. M. Pichkhadze ◽  
G. S. Smagulova ◽  
D. M. Kadyrova ◽  
K. D. Praliev ◽  
V. K. Yu
Keyword(s):  
Local Anesthetic ◽  
Anesthetic Activity ◽  
Local Anesthetic Activity ◽  
Piperidine Derivative

scholarly journals Crystal structure of 2-[4(E)-2,6-bis(4-chlorophenyl)-3-ethylpiperidin-4-ylidene]acetamide

2015 ◽  
Vol 71 (11) ◽  
pp. o832-o833
Author(s):  
K. Priya ◽  
K. Saravanan ◽  
S. Selvanayagam ◽  
S. Kabilan
Keyword(s):  
Crystal Structure ◽  
Hydrogen Bonds ◽  
Chair Conformation ◽  
Piperidine Ring ◽  
Π Interactions ◽  
Piperidine Derivative

In the title piperidine derivative, C21H22Cl2N2O, the piperidine ring adopts a chair conformation. The chlorophenyl rings are oriented at an angle of 45.59 (14)° with respect to each other. In the crystal, molecules are linkedviaN—H...O hydrogen bonds, formingC(4) chains along [100]. The chains are linked by C—H...O hydrogen bonds, forming sheets parallel to theabplane. Within the sheets, there are N—H...π interactions present. The crystal studied was refined as an inversion twin.

Synthesis and evaluation of a 18F-labeled spirocyclic piperidine derivative as promising σ1 receptor imaging agent

2014 ◽  
Vol 22 (19) ◽  
pp. 5270-5278 ◽  
Author(s):  
Yuan-Yuan Chen ◽  
Xia Wang ◽  
Jin-Ming Zhang ◽  
Winnie Deuther-Conrad ◽  
Xiao-Jun Zhang ◽  
...  
Keyword(s):  
Imaging Agent ◽  
Receptor Imaging ◽  
Piperidine Derivative ◽  
Σ1 Receptor
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