Effectiveness of sarolaner in the clinical management of furuncular myiasis in dogs naturally infested with Dermatobia hominis (Diptera: Cuterebridae)

Background The human botfly, Dermatobia hominis, is a common cause of furuncular myiasis in dogs in Latin America. Lesions can be single or multiple, each harboring an individual larva, presented as an erythematous nodule that causes pruritus and pain. Typical treatment consists of sedation for removal of larvae by surgical incision or manual pressure. Medications to kill the larva before its extraction can reduce inflammation and discomfort and provide a less traumatic larval removal. Isoxazolines are broad-spectrum ectoparasiticides with larvicidal activity previously reported in the treatment of screwworm myiasis in companion animals. The aim of this study was to evaluate the effectiveness of sarolaner as part of the clinical management of furuncular myiasis in dogs caused by D. hominis larvae. Methods Ten short-haired mixed breed dogs naturally infested with D. hominis were enrolled. Clinical diagnosis was achieved by observation of skin nodules and visualization of larval motility through the lesion orifice. Sarolaner was administered at manufacturer recommended dose for fleas and ticks. Lesions were reexamined 24 h post-treatment and assessed for viability of larvae. Larvae were removed by digital compression and identified as D. hominis. Results Seventy-five D. hominis larvae were retrieved from ten dogs. No live larvae were observed, demonstrating 100% larvicidal efficacy of sarolaner. Skin lesions were healed 30 days post-treatment and new lesions were not observed. Conclusions Sarolaner seems to be effective as larvicidal treatment for dogs with furuncular myiasis, reducing discomfort caused by the presence of the larva in the skin and facilitating its safe removal. Graphical abstract

Maggots Around Colostomy Site: A Case Report

Myiasis is a skin infection caused by developing larvae (maggots) of various Diptera fly species. The two most frequent flies that cause human infestations around the world are Dermatobia hominis (human botfly) and Cordylobia anthropophaga (tumbu fly). Maggots have been found to infest the nose, ear, orbit, tracheostomy wound, face, gums, and serous cavities, among other places. Maggots at the colostomy site are an uncommon occurrence. We report a case of maggots infestation surrounding the colostomy site. We came across a rather rare finding in a patient with advanced inoperable rectum cancer who initially complained of persistent nonspecific pain, discomfort, and foul-smelling discharge from the colostomy site. The issue at hand was identified to be maggots, and their removal alleviated the patient's symptoms. We underline the importance of regularly monitoring stoma sites to avoid maggot infestation, especially in tropical regions.

Effectiveness of Sarolaner in the Clinical Management of Furuncular Myiasis in Dogs Naturally Infested with Dermatobia Hominis (Diptera: Cuterebridae)

Background – The human botfly, Dermatobia hominis is a common cause of furuncular myiasis in dogs in Latin America. Lesions can be single or multiple, each harboring an individual larva, presented as an erythematous nodule that causes pruritus and pain. Typical treatment consists of sedation for removal of larvae by surgical incision or manual pressure. Medications to kill the larva before its extraction can reduce inflammation and discomfort, and provide a less traumatic larval removal. Isoxazolines are broad-spectrum ectoparasiticides with larvicidal activity previously reported in the treatment of screwworm myiasis in companion animals. The aim of this study was evaluate the effectiveness of sarolaner as part of the clinical management of furuncular myiasis in dogs caused by D. hominis larvae. Methods and materials – Ten short-haired mixed breed dogs naturally infested. Clinical diagnosis was achieved by observation of skin nodules and visualization of larval motility through the lesion orifice. Sarolaner was administered at manufacturer recommended dose for fleas and ticks. Lesions were reexamined 24 hours post-treatment and assessed for viability of larvae. Larvae were removed by digital compression and identified as D. hominis.Results – Seventy-five D. hominis larvae were retrieved from 10 dogs. No live larvae were observed, demonstrating 100% larvicidal efficacy of sarolaner. Skin lesions were healed 30 days post-treatment and new lesions were not observed.Conclusions – Sarolaner seems to be effective as larvicidal treatment for dogs with furuncular myiasis, reducing discomfort caused by the presence of the larva in the skin and facilitating its safe removal.

Furuncular Myiasis by Dermatobia hominis (Diptera: Oestridae) in Wild Jaguars in the Amazon Rainforest

Two individuals of the jaguar, Panthera onca (L.), were captured near the municipality of Presidente Figueiredo, Brazilian Amazon, during the years of 2017 and 2018. The jaguars presented furuncular myiasis caused by the human botfly Dermatobia hominis (L.) on the rear thighs and tail. This is the first record of infestation of D. hominis in P. onca in the Amazon region.

Cirurgia reconstrutiva no tratamento de lesões causadas por Miíase na região oronasal em canino: Relato de caso

O presente relato descreveu o tratamento de um canino macho, adulto, não castrado e sem raça definida, apresentando lesões dérmicas na região oronasal, provenientes da infestação de miíases e que, após a retirada das larvas, tratamento e cura, foi necessária a intervenção cirúrgica reconstrutiva para correção dos defeitos secundários das lesões, utilizando a técnica de retalhos do plexo subdérmico onde se obteve sucesso na escolha de toda terapêutica adotada. Miíase refere-se a presença de larvas de moscas (ordem: Díptera) nos tecidos e mucosas dos animais e humanos. No Brasil além da espécie: Dermatobia hominis conhecida popularmente como “mosca varejeira”, a espécie Cochliomyia hominivorax, vulgarmente conhecida como ‘’mosca de bicheira’’ tem grande importância sanitária. Considerada uma zoonose de notificação obrigatória pela organização internacional de epizootias (OIE). Dentre as principais causas que favorecem o aparecimento das miíases, temos: falta de higiene no ambiente, otites e feridas expostas.