Intervention Proposal for Infant Prognathism: A Case Report in a Non-Syndromic Pediatric Patient

Treating Class III malocclusions has been presently considered one of the most challenging and complex interventions of orthodontic daily practice. In this study, we report a case of a 17-month-old female patient, initially diagnosed with Angle Class III malocclusion, mandibular protrusion, and without genetic syndromes. Upon initial admission at the dental office, patient’s parents reported an inadequate bite pattern while the patient tried to eat solid food. Upon dental examination, a negative overjet of 8 millimeters was noticed and a two-phased treatment plan was established: 1. Performance of functional exercises; 2. Implementation of protractor device associated with masticatory guidance exercises. Radiographic examination and cephalometric analyses were performed throughout the case follow-up. Overall, the digital compression protocol carried out reverted the primary mandibular protrusion of -8 millimeters to +1 millimeters overbite, during the 6 months of treatment. In addition, the use of premaxillary protractor appliance increased the overbite to + 2 millimeters. The patient responded satisfactory to the treatment plan performed, and after 2 years, a proper primary occlusion, oral functionality, and facial aesthetics were improved.

Effectiveness of sarolaner in the clinical management of furuncular myiasis in dogs naturally infested with Dermatobia hominis (Diptera: Cuterebridae)

Background The human botfly, Dermatobia hominis, is a common cause of furuncular myiasis in dogs in Latin America. Lesions can be single or multiple, each harboring an individual larva, presented as an erythematous nodule that causes pruritus and pain. Typical treatment consists of sedation for removal of larvae by surgical incision or manual pressure. Medications to kill the larva before its extraction can reduce inflammation and discomfort and provide a less traumatic larval removal. Isoxazolines are broad-spectrum ectoparasiticides with larvicidal activity previously reported in the treatment of screwworm myiasis in companion animals. The aim of this study was to evaluate the effectiveness of sarolaner as part of the clinical management of furuncular myiasis in dogs caused by D. hominis larvae. Methods Ten short-haired mixed breed dogs naturally infested with D. hominis were enrolled. Clinical diagnosis was achieved by observation of skin nodules and visualization of larval motility through the lesion orifice. Sarolaner was administered at manufacturer recommended dose for fleas and ticks. Lesions were reexamined 24 h post-treatment and assessed for viability of larvae. Larvae were removed by digital compression and identified as D. hominis. Results Seventy-five D. hominis larvae were retrieved from ten dogs. No live larvae were observed, demonstrating 100% larvicidal efficacy of sarolaner. Skin lesions were healed 30 days post-treatment and new lesions were not observed. Conclusions Sarolaner seems to be effective as larvicidal treatment for dogs with furuncular myiasis, reducing discomfort caused by the presence of the larva in the skin and facilitating its safe removal. Graphical abstract

Effectiveness of Sarolaner in the Clinical Management of Furuncular Myiasis in Dogs Naturally Infested with Dermatobia Hominis (Diptera: Cuterebridae)

Background – The human botfly, Dermatobia hominis is a common cause of furuncular myiasis in dogs in Latin America. Lesions can be single or multiple, each harboring an individual larva, presented as an erythematous nodule that causes pruritus and pain. Typical treatment consists of sedation for removal of larvae by surgical incision or manual pressure. Medications to kill the larva before its extraction can reduce inflammation and discomfort, and provide a less traumatic larval removal. Isoxazolines are broad-spectrum ectoparasiticides with larvicidal activity previously reported in the treatment of screwworm myiasis in companion animals. The aim of this study was evaluate the effectiveness of sarolaner as part of the clinical management of furuncular myiasis in dogs caused by D. hominis larvae. Methods and materials – Ten short-haired mixed breed dogs naturally infested. Clinical diagnosis was achieved by observation of skin nodules and visualization of larval motility through the lesion orifice. Sarolaner was administered at manufacturer recommended dose for fleas and ticks. Lesions were reexamined 24 hours post-treatment and assessed for viability of larvae. Larvae were removed by digital compression and identified as D. hominis.Results – Seventy-five D. hominis larvae were retrieved from 10 dogs. No live larvae were observed, demonstrating 100% larvicidal efficacy of sarolaner. Skin lesions were healed 30 days post-treatment and new lesions were not observed.Conclusions – Sarolaner seems to be effective as larvicidal treatment for dogs with furuncular myiasis, reducing discomfort caused by the presence of the larva in the skin and facilitating its safe removal.

Synthesis and Characterization of Fly Ash and GBFS Based Geopolymer Material

This study investigates the synthesis and characterization of fly ash and GBFS based material using geopolymer technology. Geopolymer is a class of inorganic polymer that can be formed by the reaction between an aluminosilicate source material and an alkaline solution. The geopolymer materials are synthesized, where the GBFS are added with fly ash in some specific ratios such as 100:0, 30:70, 50:50, 70:30, and 0:100, respectively. Sodium hydroxide (NaOH) and sodium silicate (Na2SiO3) solutions are used as alkaline solutions. NaOH concentration was kept at 14 molars, and the ratio of liquid to solid is kept at 0.3. The specimens are cured at 60 oC for 24 hours. The hardened geopolymer specimens were tested by a digital compression testing machine and characterized by the FESEM technique. The hybrid C-N-A-S-H gel is the main reaction product for the fly ash and GBFS based geopolymer specimen, which plays an important role in compressive strength development.