metabolic disposition
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Pharmacokinetics and metabolic disposition of a potent and selective kynurenine monooxygenase inhibitor, CHDI-340246, in laboratory animals

Xenobiotica ◽  
2021 ◽  
Vol 51 (10) ◽  
pp. 1155-1180
Author(s):  
Vinod Khetarpal ◽  
Todd Herbst ◽  
Diana Shefchek ◽  
Steven Ash ◽  
Michael Fitzsimmons ◽  
...  
Keyword(s):  
Laboratory Animals ◽  
Metabolic Disposition

Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans

2021 ◽  
Author(s):  
Jian Meng ◽  
Hua Zhang ◽  
Jing-jing Bao ◽  
Zhen-dong Chen ◽  
Xiao-yun Liu ◽  
...  
Keyword(s):  
Covalent Inhibitor ◽  
Metabolic Disposition

Metabolic disposition of H3B-8800, an orally available small-molecule splicing modulator, in rats, monkeys, and humans

Xenobiotica ◽  
2020 ◽  
Vol 50 (9) ◽  
pp. 1101-1114
Author(s):  
Nathalie Rioux ◽  
Sherri Smith ◽  
Federico Colombo ◽  
Amy Kim ◽  
W. George Lai ◽  
...  
Keyword(s):  
Small Molecule ◽  
Metabolic Disposition

scholarly journals Mass balance, metabolic disposition, and pharmacokinetics of a single oral dose of regorafenib in healthy human subjects

2017 ◽  
Vol 81 (1) ◽  
pp. 195-206 ◽  
Author(s):  
Michael Gerisch ◽  
Frank-Thorsten Hafner ◽  
Dieter Lang ◽  
Martin Radtke ◽  
Konstanze Diefenbach ◽  
...  
Keyword(s):  
Oral Dose ◽  
Mass Balance ◽  
Single Oral Dose ◽  
Human Subjects ◽  
Healthy Human ◽  
Healthy Human Subjects ◽  
Metabolic Disposition

scholarly journals Metabolic Disposition of Luteolin Is Mediated by the Interplay of UDP-Glucuronosyltransferases and Catechol-O-Methyltransferases in Rats

2016 ◽  
Vol 45 (3) ◽  
pp. 306-315 ◽  
Author(s):  
Liping Wang ◽  
Qingwei Chen ◽  
Lijun Zhu ◽  
Qiang Li ◽  
Xuejun Zeng ◽  
...  
Keyword(s):  
Metabolic Disposition
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