Metabolic disposition of WTX101 (bis-choline tetrathiomolybdate) in a rat model of Wilson disease

Xenobiotica ◽  
2018 ◽  
Vol 49 (3) ◽  
pp. 332-338 ◽  
Author(s):  
Thomas Plitz ◽  
Lee Boyling
Keyword(s):  
Rat Model ◽  
Wilson Disease ◽  
Metabolic Disposition

Development of cell therapy strategies to overcome copper toxicity in the LEC rat model of Wilson disease

2008 ◽  
Vol 3 (2) ◽  
pp. 165-173 ◽  
Author(s):  
Harmeet Malhi ◽  
Brigid Joseph ◽  
Michael L Schilsky ◽  
Sanjeev Gupta
Keyword(s):  
Cell Therapy ◽  
Rat Model ◽  
Wilson Disease ◽  
Copper Toxicity ◽  
Therapy Strategies

scholarly journals Liver mitochondrial membrane crosslinking and destruction in a rat model of Wilson disease

2011 ◽  
Vol 121 (4) ◽  
pp. 1508-1518 ◽  
Author(s):  
Hans Zischka ◽  
Josef Lichtmannegger ◽  
Sabine Schmitt ◽  
Nora Jägemann ◽  
Sabine Schulz ◽  
...  
Keyword(s):  
Rat Model ◽  
Wilson Disease ◽  
Mitochondrial Membrane

scholarly journals Methanobactin reverses acute liver failure in a rat model of Wilson disease

2016 ◽  
Vol 126 (7) ◽  
pp. 2721-2735 ◽  
Author(s):  
Josef Lichtmannegger ◽  
Christin Leitzinger ◽  
Ralf Wimmer ◽  
Sabine Schmitt ◽  
Sabine Schulz ◽  
...  
Keyword(s):  
Liver Failure ◽  
Acute Liver Failure ◽  
Rat Model ◽  
Wilson Disease

scholarly journals PET with 64Cu-Histidine for Noninvasive Diagnosis of Biliary Copper Excretion in Long-Evans Cinnamon Rat Model of Wilson Disease

2012 ◽  
Vol 53 (6) ◽  
pp. 961-968 ◽  
Author(s):  
R. Bahde ◽  
S. Kapoor ◽  
K. K. Bhargava ◽  
M. L. Schilsky ◽  
C. J. Palestro ◽  
...  
Keyword(s):  
Rat Model ◽  
Wilson Disease ◽  
Noninvasive Diagnosis ◽  
Copper Excretion ◽  
Long Evans

1041 Gene therapy of Wilson disease with lentiviral vectors in a rat model

Hepatology ◽  
2003 ◽  
Vol 38 ◽  
pp. 657-657
Author(s):  
U MERLE ◽  
J ENCKE ◽  
L NALDINI ◽  
W STREMMEL
Keyword(s):  
Gene Therapy ◽  
Rat Model ◽  
Wilson Disease ◽  
Lentiviral Vectors

scholarly journals Bile salt-induced pro-oxidant liver damage promotes transplanted cell proliferation for correcting Wilson disease in the Long-Evans Cinnamon rat model

Hepatology ◽  
2008 ◽  
Vol 49 (5) ◽  
pp. 1616-1624 ◽  
Author(s):  
Brigid Joseph ◽  
Sorabh Kapoor ◽  
Michael L. Schilsky ◽  
Sanjeev Gupta
Keyword(s):  
Cell Proliferation ◽  
Bile Salt ◽  
Liver Damage ◽  
Rat Model ◽  
Wilson Disease ◽  
Long Evans

The biogenic methanobactin is an effective chelator for copper in a rat model for Wilson disease

2011 ◽  
Vol 25 (1) ◽  
pp. 36-41 ◽  
Author(s):  
Karl H. Summer ◽  
Josef Lichtmannegger ◽  
Nathan Bandow ◽  
Don W. Choi ◽  
Alan A. DiSpirito ◽  
...  
Keyword(s):  
Rat Model ◽  
Wilson Disease
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