This chapter examines how the global circulation of sexology intertwined with communism and national independence by focusing on the writings of American journalist Agnes Smedley as well as the letters written to her by the Indian revolutionary Bakar Ali Mirza. More specifically, it considers sexual science's connections to leftist psychoanalysis and to the Indian independence movement during the 1920s. It discusses Smedley's self-conscious mobilization of the language of sexual science as a path toward revolution and modern selfhood, doing so by shuttling between India, Germany, China, and the United States. The Berlin–India nexus and Mirza's correspondence with Smedley highlight the intrinsic interrelationships among the liberational rhetoric of leftist politics, feminism, sexual rights, national independence, and psychoanalytic introspection. The chapter also considers how Smedley and her Indian revolutionary interlocutors negotiated new definitions of femininity, masculinity, and sexuality emerging from the global movements of sexual science, radical politics, and psychoanalysis.