An Accidental Genetic Epidemiologist

I briefly describe my early life and how, through a series of serendipitous events, I became a genetic epidemiologist. I discuss how the Elston–Stewart algorithm was discovered and its contribution to segregation, linkage, and association analysis. New linkage findings and paternity testing resulted from having a genotyping lab. The different meanings of interaction—statistical and biological—are clarified. The computer package S.A.G.E. (Statistical Analysis for Genetic Epidemiology), based on extensive method development over two decades, was conceived in 1986, flourished for 20 years, and is now freely available for use and further development. Finally, I describe methods to estimate and test hypotheses about familial correlations, and point out that the liability model often used to estimate disease heritability estimates the heritability of that liability, rather than of the disease itself, and so can be highly dependent on the assumed distribution of that liability.

MODELING OF STABLE CURRENT GENERATORS FOR MICROWAVE AMPLIFIERS

В устройствах радиосвязи и электроники усилители во многом определяют динамический диапазон и чувствительность аппаратуры. Возможно построение усилительных структур на управляемых токовых зеркалах. В работе рассмотрены варианты построения квазилинейных усилительных структур на токовых зеркалах. С помощью пакета MicroCap 11 проведено их моделирование и сравнение. In radio communication and electronics devices, amplifiers largely determine the dynamic range and sensitivity of the equipment. It is possible to build amplifying structures using controlled current mirrors (CM). The paper considers variants of construction of broadband quasi-linear amplifying structures on CM. Their comparative modeling was carried out with the help of the computer package Micro Cap 11.

Passengers' Traffic Forecast of the Nigeria Airports using the Holt-Winters Additive Model

This research work was carried out in response to the need as a result of increase in Nigeria population and the demand for air transport facilities, this research was carried out using the data of the Federal Airport Authority of Nigeria, which has a total number of 23 airports out of which four are international airports, seven are domestic airports and twelve are other domestic airports with the total number of 75,879,653 passengers between Jan. 2003 and Dec. 2011. The passengers' traffic of FAAN's data of 2003 to 2011 was collected and forecasted using the NCSS computer package to generate the Holt-Winters additive model with coefficient of determination, R2 of 90.99% and the models were used to forecast for the years 2012 to 2019 using the models.

Development of a Computer Package on Organic Chemistry for Colleges of Education Students in Nigeria

The low achievement of chemistry students in Nigerian Colleges of Education has been attributed to a number of factors including a lack of indigenous computer software for enhancing course teaching. This study therefore sought to develop and validate an instructional computer package on organic chemistry for Colleges of Education in Nigeria. The development of the package involved the use of Macromedia Flash and Macromedia Time Line and Frames on HTML platform. CorelDraw and Microsoft Word programs were used for texts and graphics, Macromedia Fireworks was used for some texts, buttons, and graphics, while Macromedia Flash was utilised for animations. In the end, an organic chemistry computer instructional package (OCIP) has been produced and validated. It is recommended among others that lecturers teaching organic chemistry to first year College of Education students should make use of the developed package to improve the understanding of the course by the students.

Soft Uni-Abel-Grassmann's Groups

In this paper, we define soft union AG-group (abbreviated as soft uni-AG-group).We also define e-set and a-inclusion of soft uni-AG-groups, normal soft uni-AG-subgroups, conjugate of soft uni-AG-groups and commutators of AG-groups. We investigate various properties of these notions and provide a variety of relevant examples that are produced by a computer package GAP to illustrate these notations completely.