This chapter begins with a definition of isomorphism, and then introduces the Push-Through Construction, which allows us to generate many distinct isomorphic copies of a model. Benacerraf and Putnam have used this construction to raise certain problems for realism and the determinacy of reference. These problems seem most threatening in the case of mathematics, where nothing like causation could help pin down reference. In this connection, we introduce Putnam’s famous just-more-theory manoeuvre for the first time, and a position which is vulnerable to it, namely moderate objects-platonism. We then evaluate various attempts to salvage determinacy of reference, including Shapiro’s ante rem structuralism, before outlining a supervaluationist semantics which allows for referential indeterminacy. The appendices to this chapter contain a proof that isomorphism implies elementary equivalence, and a discussion of recent work on eligibility.