Getting a (big) data-based grip on ideological change. Evidence from Belgian Dutch

In this paper we introduce a computationally enriched experimental tool designed to investigate language ideology (change). In a free response experiment, 211 respondents returned three adjectives in reaction to the labels for five regional varieties, one ethnic variety and two supra-regional varieties of Belgian Dutch, as well as the standard accent of Netherlandic Dutch. Valence information (pertaining to the positive/negative character of the responses) and big data–based distributional analysis (to detect semantic similarity between the responses) were used to cluster the response adjectives into 11 positive and 11 negative evaluative dimensions. Correspondence analysis was subsequently used to compute and visualize the associations between these evaluative dimensions and the investigated language labels, in order to generate “perceptual maps” of the Belgian language repertoire. Contrary to our expectations, these maps unveiled not only the dominant value system which drives standard usage, but also the competing ideology which frames the increasingly occurring non-standard forms. In addition, they revealed a much richer stratification than the “one variety good, all other varieties bad” dichotomy we had anticipated: while VRT-Dutch remains the superior (albeit increasingly virtual) standard for Belgian Dutch, the stigmatized colloquial variety Tussentaal is gradually being accepted as a practical lingua franca, and the Ghent-accent is boosted by modern prestige (dynamism) features. Even more crucially, separate perceptual maps for the older and younger respondents lay bare generational change: there is a growing conceptual proximity between VRT-Dutch and Tussentaal in the younger perceptions.

Electroconvulsive therapy stimulus titration: Not all it seems

Objective: To examine the provenance and implications of seizure threshold titration in electroconvulsive therapy. Background: Titration of seizure threshold has become a virtual standard for electroconvulsive therapy. It is justified as individualisation and optimisation of the balance between efficacy and unwanted effects. Result: Present day threshold estimation is significantly different from the 1960 studies of Cronholm and Ottosson that are its usual justification. The present form of threshold estimation is unstable and too uncertain for valid optimisation or individualisation of dose. Threshold stimulation (lowest dose that produces a seizure) has proven therapeutically ineffective, and the multiples applied to threshold to attain efficacy have never been properly investigated or standardised. The therapeutic outcomes of threshold estimation (or its multiples) have not been separated from simple dose effects. Threshold estimation does not optimise dose due to its own uncertainties and the different short-term and long-term cognitive and memory effects. Potential harms of titration have not been examined. Conclusion: Seizure threshold titration in electroconvulsive therapy is not a proven technique of dose optimisation. It is widely held and practiced; its benefit and harmlessness assumed but unproven. It is a prematurely settled answer to an unsettled question that discourages further enquiry. It is an example of how practices, assumed scientific, enter medicine by obscure paths.

Analysis of Pu by Virtual-standard WDS-EPMA. Results of an Interlaboratory Round-robin Test

Extended abstract of a paper presented at Microscopy and Microanalysis 2008 in Albuquerque, New Mexico, USA, August 3 – August 7, 2008