In order to improve the service life of copper crystallizer, a layer of Ni-based alloy on thick copperplate surface was performed by plasma spray process, and then YAG pulsed laser was used to remelt spray coating. Microstructure analysis, hardness test, and the wear resistance comparison experiments were taken to the specimen. The result shown that the Ni-based alloy cladding, metallurgy bonding with the copperplate, can be performed by taking the method of the YAG laser remelt technology; the structure of the cladding is compact, without defects such as pores and cracks. The micro hardness of cladding zone is between 450-490HV, which is much higher than that of the copper substrate (about 90 HV). The wear tests showed the laser cladding layer performed 14 times higher wear resistance compared to copper substrate.