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scholarly journals KSP Inhibitor SB-743921

2020 ◽  
Author(s):  
Keyword(s):  
Ksp Inhibitor

scholarly journals KSP Inhibitor AZD4877

2020 ◽  
Author(s):  
Keyword(s):  
Ksp Inhibitor

Abstract 4828: Anti-tumor activity of BAY-943, an anti-IL3RA ADC with a novel KSP inhibitor payload, in CDX and PDX AML models

2019 ◽  
Author(s):  
Anette Sommer ◽  
Dennis Kirchhoff ◽  
Antje M. Wengner ◽  
Beatrix Stelte-Ludwig ◽  
Hans-Georg Lerchen ◽  
...  
Keyword(s):  
Anti Tumor Activity ◽  
Ksp Inhibitor

Abstract 4825: Preclinical characterization of BAY-924, a first in class ADC targeting CXCR5-positive B-cell malignancies, with a KSP inhibitor as novel payload

2019 ◽  
Author(s):  
Sarah Johannes ◽  
Stefanie Hammer ◽  
Stephan Maersch ◽  
Hans-Georg Lerchen ◽  
Beatrix Stelte-Ludwig ◽  
...  
Keyword(s):  
B Cell ◽  
B Cell Malignancies ◽  
Ksp Inhibitor

Abstract 4825: Preclinical characterization of BAY-924, a first in class ADC targeting CXCR5-positive B-cell malignancies, with a KSP inhibitor as novel payload

2019 ◽  
Author(s):  
Sarah Johannes ◽  
Stefanie Hammer ◽  
Stephan Maersch ◽  
Hans-Georg Lerchen ◽  
Beatrix Stelte-Ludwig ◽  
...  
Keyword(s):  
B Cell ◽  
B Cell Malignancies ◽  
Ksp Inhibitor

Abstract 4828: Anti-tumor activity of BAY-943, an anti-IL3RA ADC with a novel KSP inhibitor payload, in CDX and PDX AML models

2019 ◽  
Author(s):  
Anette Sommer ◽  
Dennis Kirchhoff ◽  
Antje M. Wengner ◽  
Beatrix Stelte-Ludwig ◽  
Hans-Georg Lerchen ◽  
...  
Keyword(s):  
Anti Tumor Activity ◽  
Ksp Inhibitor

scholarly journals KSP inhibitor SB743921 inhibits growth and induces apoptosis of breast cancer cells by regulating p53, Bcl-2, and DTL

2016 ◽  
Vol 27 (9) ◽  
pp. 863-872 ◽  
Author(s):  
Li Zhu ◽  
Fengjun Xiao ◽  
Yue Yu ◽  
Hua Wang ◽  
Min Fang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Ksp Inhibitor

scholarly journals A Novel KSP Inhibitor, KPYB10602, Induces Mitotic Arrest and Cell Death in Breast Cancer Cells

2016 ◽  
Vol 7 (2) ◽  
pp. 105-116
Author(s):  
Seiko Kojima-Tsuchiya ◽  
Yuki Ohta ◽  
Mitsuko Takenaga ◽  
Jun Niimi ◽  
Daiki Watanabe ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Death ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Mitotic Arrest ◽  
Ksp Inhibitor

scholarly journals KSP inhibitor SB743921 induces death of multiple myeloma cells via inhibition of the NF-κB signaling pathway

BMB Reports ◽  
2015 ◽  
Vol 48 (10) ◽  
pp. 571-576 ◽  
Author(s):  
In-Sung Song ◽  
Yu Jeong Jeong ◽  
Bayalagmaa Nyamaa ◽  
Seung Hun Jeong ◽  
Hyoung Kyu Kim ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Signaling Pathway ◽  
Myeloma Cells ◽  
Ksp Inhibitor

Potential new chemotherapy strategy for human ovarian carcinoma with a novel KSP inhibitor

2015 ◽  
Vol 463 (3) ◽  
pp. 222-228 ◽  
Author(s):  
Mitsuko Takenaga ◽  
Yuki Yamamoto ◽  
Tomoki Takeuchi ◽  
Yuki Ohta ◽  
Yukie Tokura ◽  
...  
Keyword(s):  
Ovarian Carcinoma ◽  
Human Ovarian Carcinoma ◽  
Chemotherapy Strategy ◽  
Ksp Inhibitor
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