tunable pores
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Author(s):  
Junjie Yang ◽  
Xiaoyan Zhang ◽  
Boran Zhang ◽  
Fuming Liu ◽  
Wenhao Li ◽  
...  


Author(s):  
Weilin Zhang ◽  
Jianqiang Wang ◽  
Xiaolan Geng ◽  
Li Liu ◽  
Fu Liu


Author(s):  
Zeyu Shi ◽  
Jianhui Zhang ◽  
Cheng Fang ◽  
Xi Chen ◽  
Zhishan Zhang ◽  
...  


2021 ◽  
Vol 30 (3) ◽  
pp. 1759-1767
Author(s):  
Xiang Yue ◽  
Rui Hu ◽  
Jiqiu Qi ◽  
Yezeng He ◽  
Qingkun Meng ◽  
...  


2021 ◽  
Vol 618 ◽  
pp. 118732
Author(s):  
Jian-Wei Guo ◽  
Chih-Feng Wang ◽  
Juin-Yih Lai ◽  
Chien-Hsing Lu ◽  
Jem-Kun Chen


Polymers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2156
Author(s):  
Fang-Chang Tsai ◽  
Chih-Feng Huang ◽  
Chi-Jung Chang ◽  
Chien-Hsing Lu ◽  
Jem-Kun Chen

Polystyrene nanospheres (PNs) were embedded in bovine skin gelatin gels with a poly(N-isopropylacrylamide) (PNIPAAm) network, which were denoted as NGHHs, to generate thermoresponsive behavior. When 265 nm PNs were exploited to generate the pores, bovine skin gelatin extended to completely occupy the pores left by PNs below the lower critical solution temperature (LCST), forming a pore-less structure. Contrarily, above the LCST, the collapse of hydrogen bonding between bovine skin gelatin and PNIPAAm occurred, resulting in pores in the NGHH. The behavior of pore closing and opening below and above the LCST, respectively, indicates the excellent drug gating efficiency. Amoxicillin (AMX) was loaded into the NGHHs as smart antibiotic gating due to the pore closing and opening behavior. Accordingly, E. coli. and S. aureus were exploited to test the bacteria inhibition ratio (BIR) of the AMX-loaded NGHHs. BIRs of NGHH without pores were 48% to 46.7% at 25 and 37 °C, respectively, for E. coli during 12 h of incubation time. The BIRs of nanoporous NGHH could be enhanced from 61.5% to 90.4% providing a smart antibiotic gate of bovine skin gelatin gels against inflammation from infection or injury inflammation.



2018 ◽  
Vol 1 (3) ◽  
pp. 1239-1251 ◽  
Author(s):  
Yifan Yao ◽  
Yihua Zhu ◽  
Shunan Zhao ◽  
Jianhua Shen ◽  
Xiaoling Yang ◽  
...  


2017 ◽  
Vol 9 (27) ◽  
pp. 22388-22397 ◽  
Author(s):  
Michael G. Fischer ◽  
Xiao Hua ◽  
Bodo D. Wilts ◽  
Ilja Gunkel ◽  
Thomas M. Bennett ◽  
...  


2016 ◽  
Vol 28 (19) ◽  
pp. 7134-7144 ◽  
Author(s):  
Jun Shao ◽  
Songwang Yang ◽  
Lei Lei ◽  
Qipeng Cao ◽  
Yu Yu ◽  
...  


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