dopamine analogues
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Biochemistry ◽  
2021 ◽  
Author(s):  
Alexander M. Goldberg ◽  
Miranda K. Robinson ◽  
Erykah S. Starr ◽  
Ryan N. Marasco ◽  
Alexa C. Alana ◽  
...  


2019 ◽  
Vol 16 (10) ◽  
pp. 2211-2220 ◽  
Author(s):  
Tehmina Fiaz ◽  
Shazia Perveen ◽  
Nasreen Fatima


2019 ◽  
Vol 26 (2) ◽  
pp. R95-R108 ◽  
Author(s):  
G Mantovani ◽  
D Treppiedi ◽  
E Giardino ◽  
R Catalano ◽  
F Mangili ◽  
...  

Although generally benign, pituitary tumors are frequently locally invasive, with reduced success of neurosurgery and unresponsive to pharmacological treatment with somatostatin or dopamine analogues. The molecular basis of the different biological behavior of pituitary tumors are still poorly identified, but a body of work now suggests that the activity of specific cytoskeleton proteins is a key factor regulating both the invasiveness and drug resistance of these tumors. This review recapitulates the experimental evidence supporting a role for the actin-binding protein filamin A (FLNA) in the regulation of somatostatin and dopamine receptors expression and signaling in pituitary tumors, thus in determining the responsiveness to currently used drugs, somatostatin analogues and dopamine receptor type 2 agonists. Regarding the regulation of invasive behavior of pituitary tumoral cells, we bring evidence to the role of the actin-severing protein cofilin, whose activation status may be modulated by dopaminergic and somatostatinergic drugs, through FLNA involvement. Molecular mechanisms involved in the regulation of FLNA expression and function in pituitary tumors will also be discussed.



Langmuir ◽  
2016 ◽  
Vol 32 (38) ◽  
pp. 9873-9882 ◽  
Author(s):  
Huamin Hu ◽  
Jason Christopher Dyke ◽  
Brett Allen Bowman ◽  
Ching-Chang Ko ◽  
Wei You


2015 ◽  
Vol 10 (12) ◽  
pp. 1934578X1501001 ◽  
Author(s):  
Zhi-Bo Chu ◽  
Jun Chang ◽  
Ying Zhu ◽  
Xun Sun

One new bifuran derivative (1), together with fourteen known compounds, were isolated from Cordyceps cicadae X. Q. Shing. The known compounds included nine nucleosides, uracil (2), uridine (3), 2′-deoxyuridine (4), 2′-deoxyinosine (5), guanosine (6), 2′-deoxyguanosine (7), thymidine (8), adenosine (9), and 2′-deoxyadenosine (10); three amino acids tryptophan (11), phenylalanine (12), and tyrosine (13); and two dopamine analogues N-acetylnoradrenaline (14) and its dimer, trans–2-(3′,4′-dihydroxyphenyl)-3-acetylamino-7-( N-acetyl-2″-amino-ethylene)-1,4-benzodioxane (15). Their structures were decisively elucidated by spectroscopic analysis, including 1D and 2D NMR techniques.



Synlett ◽  
2014 ◽  
Vol 25 (20) ◽  
pp. 2891-2894 ◽  
Author(s):  
Justin Maresh ◽  
Arthur Ralko ◽  
Tom Speltz ◽  
James Burke ◽  
Casey Murphy ◽  
...  
Keyword(s):  


2011 ◽  
Vol 69 (12) ◽  
pp. 1771-1773 ◽  
Author(s):  
Y. Ito ◽  
T. Mizuno ◽  
K. Yoshino ◽  
H.S. Ban ◽  
H. Nakamura ◽  
...  


ChemMedChem ◽  
2011 ◽  
Vol 6 (6) ◽  
pp. 1024-1040 ◽  
Author(s):  
Lisa A. Bonner ◽  
Uros Laban ◽  
Benjamin R. Chemel ◽  
Jose I. Juncosa ◽  
Markus A. Lill ◽  
...  


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