scholarly journals Chemical Constituents of Cordyceps cicadae

2015 ◽  
Vol 10 (12) ◽  
pp. 1934578X1501001 ◽  
Author(s):  
Zhi-Bo Chu ◽  
Jun Chang ◽  
Ying Zhu ◽  
Xun Sun
Keyword(s):  
Amino Acids ◽  
Spectroscopic Analysis ◽  
Chemical Constituents ◽  
2D Nmr ◽  
Cordyceps Cicadae ◽  
Nmr Techniques ◽  
Dopamine Analogues

One new bifuran derivative (1), together with fourteen known compounds, were isolated from Cordyceps cicadae X. Q. Shing. The known compounds included nine nucleosides, uracil (2), uridine (3), 2′-deoxyuridine (4), 2′-deoxyinosine (5), guanosine (6), 2′-deoxyguanosine (7), thymidine (8), adenosine (9), and 2′-deoxyadenosine (10); three amino acids tryptophan (11), phenylalanine (12), and tyrosine (13); and two dopamine analogues N-acetylnoradrenaline (14) and its dimer, trans–2-(3′,4′-dihydroxyphenyl)-3-acetylamino-7-( N-acetyl-2″-amino-ethylene)-1,4-benzodioxane (15). Their structures were decisively elucidated by spectroscopic analysis, including 1D and 2D NMR techniques.

Isolation of New Glycosides from Anemarrhena Asphodeloides Rhizome and Screening of their Anticancer Activity

2019 ◽  
Vol 16 (6) ◽  
pp. 474-477 ◽  
Author(s):  
Pham Van Khang ◽  
Nguyen Thi Hien Lan ◽  
Le Quang Truong ◽  
Mai Thi Minh Chau ◽  
Mai Xuan Truong ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Spectral Data ◽  
Cell Lines ◽  
Cancer Cell ◽  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Ic50 Values ◽  
Nmr Techniques ◽  
Inhibitory Activities ◽  
Anemarrhena Asphodeloides

In this report, two new steroidal glycosides were isolated and determined from n-butanol fraction of A.asphodeloides. The structures were confirmed in comparison with the spectral data of known compounds by using different spectroscopic analysis approaches including 1D & 2D-NMR techniques and HRMS. The anti-proliferation screening against cancer cell lines A549 and HeLa indicated that compound 1 exhibited good inhibitory activities with IC50 values of 0.79 and 0.55 µg/mL, respectively.

scholarly journals Chemical Constituents of the Terrestrial Stems of Ephedra sinica and their PPAR-γ Ligand-Binding Activity

2020 ◽  
Vol 7 (01) ◽  
pp. e12-e16
Author(s):  
Yukiko Matsuo ◽  
Mayu Sasaki ◽  
Haruhiko Fukaya ◽  
Katsunori Miyake ◽  
Riko Takeuchi ◽  
...  
Keyword(s):  
Ligand Binding ◽  
Spectroscopic Analysis ◽  
Binding Assay ◽  
Chemical Constituents ◽  
2D Nmr ◽  
Binding Activity ◽  
Ephedra Sinica ◽  
Ppar Γ ◽  
Bioassay Guided Fractionation ◽  
Ligand Binding Activity

AbstractBioassay-guided fractionation of the MeOH extract of Ephedra sinica terrestrial stems, using a PPAR-γ ligand binding assay, resulted in the isolation of 10 compounds, including one new bisabolane-type sesquiterpenoid (10). The structure of the new compound was determined by extensive spectroscopic analysis, including two-dimensional (2D) NMR. Among the isolated compounds, the sitosterol derivatives (1 and 2), flavonoid glucoside (7), and the new sesquiterpenoid (10), showed significant PPAR-γ ligand-binding activity.

scholarly journals A Novel Phenolic Compound from Phyllanthus emblica

2013 ◽  
Vol 8 (4) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
Gaimei She ◽  
Ruiyang Cheng ◽  
Lei Sha ◽  
Yixia Xu ◽  
Renbin Shi ◽  
...  
Keyword(s):  
Phenolic Compound ◽  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Phyllanthus Emblica ◽  
Mucic Acid ◽  
Nmr Techniques

A new compound, mucic acid 3- O-gallate (1), was isolated from the fruit of Phyllanthus emblica L, together with 5 known compounds (2-6). Their structures were elucidated on the basis of spectroscopic analysis, including 1D and 2D NMR techniques, and by comparison with literature data.

MWL fraction with a high concentration of lignin-carbohydrate linkages: Isolation and 2D NMR spectroscopic analysis

Holzforschung ◽  
2007 ◽  
Vol 61 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Mikhail Yu. Balakshin ◽  
Ewellyn A. Capanema ◽  
Hou-min Chang
Keyword(s):  
Loblolly Pine ◽  
Spectroscopic Analysis ◽  
Direct Detection ◽  
2D Nmr ◽  
Side Chain ◽  
High Concentration ◽  
Hmbc Correlation ◽  
Nmr Techniques ◽  
C Nmr ◽  
Hmbc Technique

Abstract A preparation enriched in lignin-carbohydrate fragments (LCC-AcOH) was isolated in the course of purification of loblolly pine crude milled wood lignin (MWL). The preparation contained approximately equal amounts of lignin and carbohydrates, with high amounts of arabinose and galactose compared to their levels in wood. LCC-AcOH was investigated by 2D 1H-13C (HMQC and HMBC) correlation NMR techniques and quantitative 13C NMR. The HMQC spectra allowed direct detection of phenyl glycoside, ester and benzyl ether lignin-carbohydrates linkages in high amounts. The assignment of these structures was supported by the HMBC technique. It is noteworthy that in the ester lignin-carbohydrate linkages, a uronic acid residue was attached not to the benzylic position of lignin, as commonly believed, but to the γ-position of the side chain.

scholarly journals Nine Unique Iridoids and Iridoid Glycosides From Patrinia scabiosaefolia

2021 ◽  
Vol 9 ◽  
Author(s):  
Zhenhua Liu ◽  
Yun Niu ◽  
Li Zhou ◽  
Lijun Meng ◽  
Sitan Chen ◽  
...  
Keyword(s):  
Spectroscopic Analysis ◽  
Chemical Constituents ◽  
Iridoid Glycosides ◽  
Chinese Herb ◽  
2D Nmr ◽  
Iridoid Glycoside ◽  
Cytotoxic Activities ◽  
Medicinal Value ◽  
Patrinia Scabiosaefolia ◽  
Mcf 7

Patrinia scabiosaefolia is a medical and edible Chinese herb with high nutritional and medicinal value. The continuing study of its chemical constituents led to the discovery of nine unique iridoids and iridoid glycosides, including three new iridoids (1-3) and six previously unknown irioid glycosides (5-10), and one known compound (4). Among them, compound 1 was a deformed iridoid, while compounds 3, 5-7, and 10 formed a new ring in their skeletons which was uncommon in this genus. For compound 3, the new ring existed between C-3 and C-10, while a 1,3-dioxane appeared between C-7 and C-10 in compounds 5-7 and 10. Moreover, compound 10 was a bis-iridoid glycoside, which was the first reported in P. scabiosaefolia. And the sugar of irioid glycosides (5-10) was glucose at C-11, except in 9 which had a 5-deoxyglucose moiety. All their structures were confirmed based on the extensive spectroscopic analysis, including IR, UV, HR-ESI-MS, ECD, and 1D- and 2D-NMR experiments. Their cytotoxic activities against HL-60, A-549, SMMC-7721, MCF-7, SW480 were also tested.

scholarly journals Chemical Constituents of Vitex trifolia Leaves

2018 ◽  
Vol 13 (2) ◽  
pp. 1934578X1801300
Author(s):  
Ninh Khac Ban ◽  
Nguyen Thi Kim Thoa ◽  
Tran My Linh ◽  
Vu Huong Giang ◽  
Do Thi Trang ◽  
...  
Keyword(s):  
Spectroscopic Analysis ◽  
Chemical Constituents ◽  
2D Nmr ◽  
Esi Ms ◽  
Chromatographic Methods ◽  
Nmr Data

Using various chromatographic methods, one new lanostane triterpene, 3 α-hydroxylanosta-8,24 E-dien-26-oic acid (1), one new lignan, matairesinol 4'- O-β-D-glucopyranoside (2) along with five known compounds, ecdysone (3), 20-hydroxyecdysone (4), 20-hydroxyecdysone 2,3-monoacetonide (5), turkesterone (6), and polypodine B (7) were isolated from the leaves of Vitex trifolia L. Their structures were elucidated by 1D-, 2D-NMR spectroscopic analysis, HR-ESI-MS, CD, and by comparing with the NMR data reported in the literature.

scholarly journals Synthesis and structure of (R,S)-2-methyl-4-(4-nitrophenyl)-pyrano[3,2-c]chromen-5(4H)-one

2012 ◽  
Vol 32 (2) ◽  
pp. 239
Author(s):  
Rosica P. Nikolova ◽  
Boris Shivachev ◽  
Bozhana Mikhova ◽  
Bistra Stamboliyska ◽  
Kristina Mladenovska ◽  
...  
Keyword(s):  
Spectroscopic Data ◽  
Chemical Structure ◽  
Spectroscopic Analysis ◽  
2D Nmr ◽  
The Novel ◽  
Phosphoryl Chloride ◽  
Torsion Angles ◽  
X Ray ◽  
Nmr Techniques ◽  
High Yields

In this paper, the synthesis and structure of a novel pyrano[3,2-c]coumarin, which was obtained unexpectedly in a reaction of phosphoryl chloride and acenocoumarol, are presented. The chemical structure of the novel compound was elucidated by a detailed spectroscopic analysis based mainly on 1D and 2D NMR techniques. The structure was finally confirmed with a single-crystal X-ray analysis. The B3LYP/6-311+G** method correctly reproduces the bond lengths, bond angles, torsion angles, and other experimental spectroscopic data, which can be useful for investigating the characteristics of some structurally related molecules. Additionally, the title compound was obtained in high yields by performing a dehydratation reaction of acenocuomarol with acetic anhydride.  

scholarly journals A New Antimicrobial and Anticancer Peptide Producing by the Marine Deep Sediment Strain “Paenibacillus profundus” sp. nov. Sl 79

2013 ◽  
Vol 8 (3) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
Nataliya I. Kalinovskaya ◽  
Lyudmila A. Romanenko ◽  
Anatoly I. Kalinovsky ◽  
Pavel S. Dmitrenok ◽  
Sergey A. Dyshlovoy
Keyword(s):  
Amino Acids ◽  
Staphylococcus Epidermidis ◽  
Inhibitory Activity ◽  
2D Nmr ◽  
Colony Growth ◽  
Anticancer Peptide ◽  
Deep Sea Sediment ◽  
Growth Inhibitory ◽  
Growth Inhibitory Activity ◽  
Nmr Techniques

A new linear glyceryl acid derived heptapeptide (1), together with known isocoumarin antibiotic, Y-05460M-A (2), were isolated from the culture of the deep sea sediment strain Sl 79 classified as “ Paenibacillus profundus” sp. nov. Their structures were determined by 1D- and 2D- NMR techniques and ESI-MS/MS experiments. HPLC analysis of the Marfey derivatives in comparison to their analogs of authentic amino acids revealed that all amino acids in peptide 1, with an exception of Val, have the D-configuration. The compound 1 showed inhibitory activity against Staphylococcus aureus, Staphylococcus epidermidis, Bacillus subtilis, Enterococcus faecium as well as cytotoxic and moderate colony growth inhibitory activity against SK-MEL-28 cell line.

scholarly journals Isomeric Polycyclic Polyprenylated Acylphloroglucinols from the Bark of Mesua ferrea (Clusiaceae)

2017 ◽  
Vol 12 (8) ◽  
pp. 1934578X1701200
Author(s):  
Nurulfazlina Edayah Rasol ◽  
Humera Naz ◽  
Khalijah Awang ◽  
Mohamad Jemain Mohamad Ridhwan ◽  
Yap Ken Choy ◽  
...  
Keyword(s):  
Ethyl Acetate ◽  
Inhibitory Activity ◽  
Spectroscopic Analysis ◽  
Ethyl Acetate Extract ◽  
2D Nmr ◽  
Positive Control ◽  
Preparative Hplc ◽  
Nmr Techniques

Five new isomeric polycyclic polyprenylated acylphloroglucinols (PPAPs) named mesuaferroic acid A, B, C, E and F (1–5) were isolated from ethyl acetate extract of Mesua ferrea L. (Clusiaceae). The isomeric compounds were obtained after extensive chromatographic procedures mainly using preparative HPLC. Structures were established after detailed spectroscopic analysis mostly by 2D NMR techniques. Compounds 4 and 5 exhibited good α-glucosidase inhibitory activity with IC50 values of 0.43 and 0.60 mM, respectively, comparing to the positive control, 1-deoxynojirimycin (IC50 0.63 mM).

Xylogranatin E, a New Phragmalin with a Rare Oxygen Bridge between C1 and C29, from the Fruit of a Chinese Mangrove Xylocarpus granatum

2007 ◽  
Vol 62 (4) ◽  
pp. 569-572 ◽  
Author(s):  
Jun Wu ◽  
Haixin Ding ◽  
Minyi Li ◽  
Si Zhang
Keyword(s):  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Oxygen Bridge ◽  
Nmr Data ◽  
Xylocarpus Granatum ◽  
Complete Assignment ◽  
Nmr Techniques ◽  
Noesy Spectra ◽  
C Nmr

Xylogranatin E, the second phragmalin with a rare oxygen bridge between C1 and C29 found in nature, was isolated from the fruit of a Chinese mangrove, Xylocarpus granatum. Its structure was determined by spectroscopic analysis. Complete assignment of 1H and 13C NMR data of xylogranatin E was achieved by 2D NMR techniques, including 1H-1H COSY, HSQC, HMBC and NOESY spectra.

Sign in / Sign up

Export Citation Format

Share Document