Mandible Aseptic Osteonecrosis Caused by admission of the Narcotic Substances Containing Aminophosphonic Impurities: Levelling with Trilon B

The aim of our study was to correct osteosclerotic changes (aseptic osteonecrotic lesion) of mandibular bones in laboratory white rats. Changes were caused by 1 and 3 monthly intragastric administration of amino phosphonic impurity. It was formed during artisanal manufacture of meta-amphetamine. A dose was 63 mg/kg 1 time per day, and followed by exposure to 5% water solution of Trilon B at a dose of 250 mg/kg. Mandible structure was researched by light microscopy. Three additional functional indices and elements of node-strut analysis were enrolled. Indices and their abbreviations were used in accordance to Committee on Histomorphometry Nomenclature (ASBMR). It was found that intragastric administration of Trilon B at a dose of 250 mg/kg after one-month- and three-month influence of amino phosphonic impurity (by-product of methamphetamine artisanal synthesis) at a dose of 63 mg/kg led to improvements of mandible bone remodeling. Also, enhancement of processes that removed osteosclerotic changes as well as an involution of myelofibrosis took place.

X-RAY ANALYSIS OF THE MANDIBLE IN PATIENTS WITH CROSSBITE AND MANDIBULAR DISPLACEMENT

Introduction: Significant morphological and aesthetic disabilities of the face, observed during the formation of a cross bite in combination with the displacement of the mandible, prompt the doctors – orthodontists to study carefully the morphogenesis of this anomaly. The aim: Analysis of the mandible structure in patients with a cross bite and lower jaw displac ement based on the analysis of orthopantomograms. Materials and methods: For this study, the orthodontic examination of 20 patients, 18-22 years old, was made they complained about facial asymmetry, displacement of the lower jaw and a violation of the cosmetic centers. A diagnosis of the buccal cross bite form in combination with the displacement of the lower jaw was put according to the Uzhumeckiene classification. The methods used do not contradict the conclusions of the ethics commission. Results: The analysis of the obtained data indicates that the angle of the mandible has more variable (p ≤ 0,05). Go120,8º and 125,1º. Significant of the angles of the canines according to the basal arch of the lower jaw of 102,8º and 105,4º (p≤0.01) and the angle of inclination of the first permanent molars of 89,6º and 91,4º, respectively (p≤0.01). Conclusions: The obtained data indicate that there is no clear correlation between changes in the studied parameters and the localization of anomalies (left-sided, right-sided). Indicators of the angle of the lower jaw are significantly altered from the opposite direction of its displacement. The change in the angles of inclination of the canine and the first permanent molars, as occlusive compensation, is determined reliably. The more the angle of the mandible changes, the more the lower jaw moves in the transversal direction. Perhaps this is due to the asymmetric tone of masticatory muscles.

Morphological Features of the Mandible Related To Feeding Habits of Some Anostraca Species

Morphology of the molar surface of the mandibles is examined via SEM and discussed in relation to possible functions, after reviewing and reconsidering the existing literature on the subject. A comparison of mandibular (present work) and trunk limb morphology (Daborn, 1978, 1979) reveals some discrepancies between mandible structure and supposed feeding habits of some fairy shrimp species.