This chapter explains crimes against humanity. Crimes against humanity are mass crimes committed against a civilian population. Most serious is the killing of entire groups of people, which is also characteristic of genocide. Crimes against humanity target fundamental, recognised human rights, in particular life, health, freedom, and dignity. These violations of individual rights become international crimes when they are committed as part of a widespread or systematic attack on a civilian population. The chapter discusses the history and structure of the crime, as well as protected interests. It then presents the contextual element of this crime, which is an attack on a civilian population as defined in the ICC Statute. After this, individual acts committed as part of a widespread or systematic attack on a civilian population are next discussed. Lastly, this chapter explores the multiplicity of offenses within this category.