Methods in Molecular Biology - Oligonucleotide-Based Therapies
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Published By Springer New York

9781493996698, 9781493996704
Latest Documents Most Cited Documents Contributed Authors Related Sources Related Keywords

Modeling and Simulation of Oligonucleotide Hybrids: Outlining a Strategy

2019 ◽  
pp. 113-126
Author(s):  
Lennart Nilsson ◽  
Alessandra Villa
Keyword(s):  
Modeling And Simulation

In Vitro Assessment of the Hepatotoxicity Potential of Therapeutic Oligonucleotides

2019 ◽  
pp. 249-259
Author(s):  
Sabine Sewing ◽  
Tanja Minz ◽  
Franziska Boess
Keyword(s):  
In Vitro Assessment

Tissue-Specific Delivery of Oligonucleotides

2019 ◽  
pp. 17-50
Author(s):  
Xin Xia ◽  
Nicolette Pollock ◽  
Jiehua Zhou ◽  
John Rossi
Keyword(s):  
Tissue Specific

Designing siRNA and Evaluating Its Effect on RNA Targets Using qPCR and Western Blot

2019 ◽  
pp. 53-72
Author(s):  
Linda Vidarsdottir ◽  
Oksana Goroshchuk ◽  
Iryna Kolosenko ◽  
Caroline Palm-Apergi
Keyword(s):  
Western Blot ◽  
Rna Targets

scholarly journals Delivery of Antisense Oligonucleotides Mediated by a Hydrogel System: In Vitro and In Vivo Application in the Context of Spinal Cord Injury

2019 ◽  
pp. 205-219
Author(s):  
Pedro M. D. Moreno ◽  
Teresa Rodrigues ◽  
Marília Torrado ◽  
Isabel F. Amaral ◽  
Ana P. Pêgo
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Antisense Oligonucleotides ◽  
Cord Injury ◽  
Hydrogel System

Identifying Suitable Target Regions and Analyzing Off-Target Effects of Therapeutic Oligonucleotides

2019 ◽  
pp. 261-282 ◽  
Author(s):  
Lykke Pedersen ◽  
Peter H. Hagedorn ◽  
Troels Koch
Keyword(s):  
Suitable Target ◽  
Target Effects

Click-Shielded and Targeted Lipopolyplexes

2019 ◽  
pp. 141-164 ◽  
Author(s):  
Philipp Michael Klein ◽  
Ernst Wagner

ADME: Assessing Pharmacokinetic–Pharmacodynamic Parameters of Oligonucleotides

2019 ◽  
pp. 317-339
Author(s):  
Rasmus Jansson-Löfmark ◽  
Christine Ahlström ◽  
Peter Gennemark

Chemical Development of Therapeutic Oligonucleotides

2019 ◽  
pp. 3-16 ◽  
Author(s):  
Karin E. Lundin ◽  
Olof Gissberg ◽  
C. I. Edvard Smith ◽  
Rula Zain
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