Structural Biology in Drug Discovery
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9781118681015, 9781118681121
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A Comprehensive Review on Mycobacterium tuberculosis Targets and Drug Development from a Structural Perspective

2020 ◽  
pp. 545-566 ◽  
Author(s):  
Jean‐Denis Pedelacq ◽  
Minh Chau Nguyen ◽  
Thomas C. Terwilliger ◽  
Lionel Mourey
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Drug Development ◽  
Comprehensive Review ◽  
Structural Perspective

NMR Studies of Protein–Small Molecule Interactions for Drug Discovery

2020 ◽  
pp. 325-345
Author(s):  
Daniel F. Wyss ◽  
Edward R. Zartler
Keyword(s):  
Drug Discovery ◽  
Small Molecule ◽  
Nmr Studies ◽  
Molecule Interactions

Epigenetic Proteins as Emerging Drug Targets

2020 ◽  
pp. 423-448
Author(s):  
P. Ann Boriack‐Sjodin
Keyword(s):  
Drug Targets

Allostery as Structure‐Encoded Collective Dynamics

2020 ◽  
pp. 125-141 ◽  
Author(s):  
Indira H. Shrivastava ◽  
Chang Liu ◽  
Anindita Dutta ◽  
Ahmet Bakan ◽  
Ivet Bahar
Keyword(s):  
Collective Dynamics

Membrane Protein Crystallization

2020 ◽  
pp. 187-210
Author(s):  
Ching‐Ju Tsai ◽  
Gebhard F. X. Schertler
Keyword(s):  
Membrane Protein ◽  
Protein Crystallization ◽  
Membrane Protein Crystallization

Targeting Protein–Protein Interactions Perspective

2020 ◽  
pp. 479-502
Author(s):  
Chun‐wa Chung ◽  
Michael M. Hann
Keyword(s):  
Protein Interactions ◽  
Protein Protein Interactions

Biophysical Assessment of Target Protein Quality in Structure‐Based Drug Discovery

2020 ◽  
pp. 143-164
Author(s):  
Arne Christian Rufer ◽  
Michael Hennig
Keyword(s):  
Drug Discovery ◽  
Protein Quality ◽  
Target Protein
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