Primary Reticulum Cell Sarcoma of the Brain in Wiskott-Aldrich Syndrome

1977 ◽  
Vol 34 (10) ◽  
pp. 633 ◽  
Author(s):  
Lawrence M. Model
PEDIATRICS ◽  
1974 ◽  
Vol 54 (4) ◽  
pp. 455-455
Author(s):  
Robert W. Miller

Congenital immunodeficiency predisposes patients with Wiskott-Aldrich syndrome to lymphoreticular neoplasia. A 19-year-old boy with the syndrome has recently been reported with reticulum cell sarcoma confined to the brain, a very rare site for this neoplasm (Heidelberger, K. P., and LoGolvan, D. P., Cancer, 33:281-284, 1974). The same rare neoplasm has been observed in 13 renal-transplant recipients on immunosuppressive therapy (Hoover, R. N., and Fraumeni, J. F., Jr., Lancet, II:55, 1973). The patient with Wiskott-Aldrich syndrome and reticulum cell sarcoma of the brain, unlike those with ataxia-telangiectasia and lymphoma, experienced no adverse reaction to radiotherapy or chemotherapy.


1978 ◽  
Vol 71 (3) ◽  
pp. 338-339 ◽  
Author(s):  
EDWARD J. FINE ◽  
SRINIVASAN S. MANI

1975 ◽  
Vol 210 (3) ◽  
pp. 143-150 ◽  
Author(s):  
Masashi Fukui ◽  
Yuzo Yamakawa ◽  
Tatsusuke Yamasaki ◽  
Katsutoshi Kitamura ◽  
Takeshi Tabira ◽  
...  

1972 ◽  
Vol 73 (3) ◽  
pp. 431-436 ◽  
Author(s):  
Roger W. Neault ◽  
Robert E. Van Scoy ◽  
Haruo Okazaki ◽  
Collin S. Maccarty

Radiology ◽  
1979 ◽  
Vol 130 (1) ◽  
pp. 165-170 ◽  
Author(s):  
Dieter R. Enzmann ◽  
John Krikorian ◽  
David Norman ◽  
Richard Kramer ◽  
James Pollock ◽  
...  

1971 ◽  
Vol 35 (4) ◽  
pp. 406-415 ◽  
Author(s):  
Carl H. Gunderson ◽  
James Henry ◽  
Nathan Malamud

✓ Five patients are described with cerebral microglioma or reticulum cell sarcoma. The tumors varied from local neoplasms to multicentric or miliary foci. One of these patients is the second case reported of a microglioma associated with Waldenström's macroglobulinemia. Serum electrophoresis on the other four patients did not reveal any consistent abnormality or pattern. Immunoglobulin studies performed on three of the five patients confirmed Waldenström's syndrome in one, revealed an elevated IgA globulin in a second, and was normal in a third. Cerebrospinal fluid findings included elevated spinal fluid protein in all five patients. The brain scan was abnormal in all four cases so tested. Arteriograms in four patients demonstrated tumor blushes indicative of increased numbers of enlarged vessels. The relationship between reticulum cell sarcomas originating in the central nervous system and those originating elsewhere is discussed.


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