Plasma globulin determinations in patients with microglioma

1971 ◽  
Vol 35 (4) ◽  
pp. 406-415 ◽  
Author(s):  
Carl H. Gunderson ◽  
James Henry ◽  
Nathan Malamud

✓ Five patients are described with cerebral microglioma or reticulum cell sarcoma. The tumors varied from local neoplasms to multicentric or miliary foci. One of these patients is the second case reported of a microglioma associated with Waldenström's macroglobulinemia. Serum electrophoresis on the other four patients did not reveal any consistent abnormality or pattern. Immunoglobulin studies performed on three of the five patients confirmed Waldenström's syndrome in one, revealed an elevated IgA globulin in a second, and was normal in a third. Cerebrospinal fluid findings included elevated spinal fluid protein in all five patients. The brain scan was abnormal in all four cases so tested. Arteriograms in four patients demonstrated tumor blushes indicative of increased numbers of enlarged vessels. The relationship between reticulum cell sarcomas originating in the central nervous system and those originating elsewhere is discussed.

1980 ◽  
Vol 53 (5) ◽  
pp. 714-716 ◽  
Author(s):  
Ivy Benjamin ◽  
Mary E. S. Case

✓ A patient is presented with reticulum-cell sarcoma of the brain and a large metastasis to the heart.


1974 ◽  
Vol 41 (2) ◽  
pp. 235-239 ◽  
Author(s):  
Eun-Sook Cho ◽  
Eugene Connolly ◽  
Robert S. Porro

✓ A case of primary reticulum cell sarcoma of the brain (microgliomatosis) is reported in a kidney transplant recipient treated with immunosuppressants, the second such case seen at this institution. Hypotheses for the mechanism of lymphoma development in this situation are reviewed, and the remarkable predilection for the brain is pointed out.


1975 ◽  
Vol 42 (3) ◽  
pp. 346-348 ◽  
Author(s):  
Patrick R. R. Clarke ◽  
Michael Saunders

✓ The authors record the case histories of two patients originally diagnosed as having the Guillain-Barré syndrome, who responded to steroid therapy and were subsequently shown to have reticulum cell sarcomas. The dangers of attaching significance to steroid-induced remissions are stressed.


1977 ◽  
Vol 47 (4) ◽  
pp. 619-622 ◽  
Author(s):  
Eugene F. Binet ◽  
Ronald F. Young

✓ A case is presented of bilateral persistent trigeminal arteries associated with reticulum cell sarcoma of the cerebellum.


1971 ◽  
Vol 34 (4) ◽  
pp. 537-543 ◽  
Author(s):  
Richard A. Lende ◽  
Wolff M. Kirsch ◽  
Ralph Druckman

✓ Cortical removals which included precentral and postcentral facial representations resulted in relief of facial pain in two patients. Because of known failures following only postcentral (SmI) ablations, these operations were designed to eliminate also the cutaneous afferent projection to the precentral gyrus (MsI) and the second somatic sensory area (SmII). In one case burning pain developed after a stroke involving the brain stem and was not improved by total fifth nerve section; prompt relief followed corticectomy and lasted until death from heart disease 20 months later. In the other case persistent steady pain that developed after fifth rhizotomy for trigeminal neuralgia proved refractory to frontal lobotomy; relief after corticectomy was immediate and has lasted 14 months. Cortical localization was established by stimulation under local anesthesia. Each removal extended up to the border of the arm representation and down to the upper border of the insula. Such a resection necessarily included SmII, and in one case responses presumably from SmII were obtained before removal. The suggestions of Biemond (1956) and Poggio and Mountcastle (1960) that SmII might be concerned with pain sensibility may be pertinent in these cases.


PEDIATRICS ◽  
1974 ◽  
Vol 54 (4) ◽  
pp. 455-455
Author(s):  
Robert W. Miller

Congenital immunodeficiency predisposes patients with Wiskott-Aldrich syndrome to lymphoreticular neoplasia. A 19-year-old boy with the syndrome has recently been reported with reticulum cell sarcoma confined to the brain, a very rare site for this neoplasm (Heidelberger, K. P., and LoGolvan, D. P., Cancer, 33:281-284, 1974). The same rare neoplasm has been observed in 13 renal-transplant recipients on immunosuppressive therapy (Hoover, R. N., and Fraumeni, J. F., Jr., Lancet, II:55, 1973). The patient with Wiskott-Aldrich syndrome and reticulum cell sarcoma of the brain, unlike those with ataxia-telangiectasia and lymphoma, experienced no adverse reaction to radiotherapy or chemotherapy.


1978 ◽  
Vol 71 (3) ◽  
pp. 338-339 ◽  
Author(s):  
EDWARD J. FINE ◽  
SRINIVASAN S. MANI

1975 ◽  
Vol 210 (3) ◽  
pp. 143-150 ◽  
Author(s):  
Masashi Fukui ◽  
Yuzo Yamakawa ◽  
Tatsusuke Yamasaki ◽  
Katsutoshi Kitamura ◽  
Takeshi Tabira ◽  
...  

1982 ◽  
Vol 56 (3) ◽  
pp. 430-434 ◽  
Author(s):  
Edwin G. Fischer ◽  
Ana Sotrel ◽  
Keasley Welch

✓ Two patients are reported who had intracerebral mass lesions composed of hemangioma and glial neoplasm. After excision, one recurred as an oligodendroglioma, and the remnant of the other remained static over a 5-year period. These lesions may represent a subgroup of cerebral hemangiomas that have the biological potential for future glial neoplastic growth. Reference is made to experimental work with polyoma virus which can induce cavernous hemangiomas in the central nervous system in mice, and which is a papovavirus. Other papovaviruses can induce ependymomas in hamsters.


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