Hedgehog Pathway Inhibitor Therapy for Locally Advanced and Metastatic Basal Cell Carcinoma

Audrey A. Jacobsen; Adam S. Aldahan; Olivia B. Hughes; Vidhi V. Shah; John Strasswimmer

doi:10.1001/jamadermatol.2016.0780

Hedgehog Pathway Inhibitor Therapy for Locally Advanced and Metastatic Basal Cell Carcinoma

JAMA Dermatology ◽

10.1001/jamadermatol.2016.0780 ◽

2016 ◽

Vol 152 (7) ◽

pp. 816 ◽

Cited By ~ 53

Author(s):

Audrey A. Jacobsen ◽

Adam S. Aldahan ◽

Olivia B. Hughes ◽

Vidhi V. Shah ◽

John Strasswimmer

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Locally Advanced ◽

Inhibitor Therapy ◽

Hedgehog Pathway ◽

Metastatic Basal Cell Carcinoma ◽

Hedgehog Pathway Inhibitor

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Abstract LB-138: Efficacy data of GDC-0449, a systemic Hedgehog pathway antagonist, in a first-in-human, first-in-class Phase I study with locally advanced, multifocal or metastatic basal cell carcinoma patients

10.1158/1538-7445.am2008-lb-138 ◽

2008 ◽

Cited By ~ 5

Author(s):

Daniel D Von Hoff ◽

Charles M Rudin ◽

Patricia M LoRusso ◽

Mitesh J Borad ◽

Ronald L Korn ◽

...

Keyword(s):

Basal Cell Carcinoma ◽

Phase I ◽

Cell Carcinoma ◽

Basal Cell ◽

Phase I Study ◽

Locally Advanced ◽

Hedgehog Pathway ◽

Efficacy Data ◽

Metastatic Basal Cell Carcinoma

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Vismodegib: First-in-Class Hedgehog Pathway Inhibitor for Metastatic or Locally Advanced Basal Cell Carcinoma

Journal of the Advanced Practitioner in Oncology ◽

10.6004/jadpro.2014.5.4.7 ◽

2014 ◽

Vol 5 (4) ◽

Cited By ~ 1

Author(s):

Nancy M. Nix, PharmD, BCPS, BCOP ◽

Olivia Burdine, PharmD ◽

Makeda Walker, PharmD

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Locally Advanced ◽

Hedgehog Pathway ◽

Hedgehog Pathway Inhibitor ◽

Advanced Basal Cell Carcinoma

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Targeting the Hedgehog Pathway for Locally Advanced and Metastatic Basal Cell Carcinoma

Current Pharmaceutical Design ◽

10.2174/1381612822666161208100325 ◽

2017 ◽

Vol 23 (4) ◽

pp. 655-659 ◽

Cited By ~ 12

Author(s):

Bita Esmaeli ◽

Vivian Yin

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Locally Advanced ◽

Hedgehog Pathway ◽

Metastatic Basal Cell Carcinoma

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Emergence of chemoresistance in a metastatic basal cell carcinoma patient after complete response to hedgehog pathway inhibitor vismodegib (GDC-0449)

Australasian Journal of Dermatology ◽

10.1111/ajd.12196 ◽

2014 ◽

Vol 55 (3) ◽

pp. 218-221 ◽

Cited By ~ 9

Author(s):

Rowena E Meani ◽

Shueh-Wen Lim ◽

Anne Lynn S Chang ◽

John W Kelly

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Complete Response ◽

Hedgehog Pathway ◽

Carcinoma Patient ◽

Metastatic Basal Cell Carcinoma ◽

Hedgehog Pathway Inhibitor

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Assessment of the adverse events related to hedgehog pathway inhibitor therapy for basal cell carcinoma: A single‐centre retrospective study

Australasian Journal of Dermatology ◽

10.1111/ajd.13488 ◽

2020 ◽

Author(s):

Alessia Villani ◽

Gabriella Fabbrocini ◽

Claudia Costa ◽

Milena Cappello ◽

Massimiliano Scalvenzi

Keyword(s):

Retrospective Study ◽

Basal Cell Carcinoma ◽

Adverse Events ◽

Cell Carcinoma ◽

Basal Cell ◽

Inhibitor Therapy ◽

Hedgehog Pathway ◽

Single Centre ◽

Hedgehog Pathway Inhibitor

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CO14. A pivotal study evaluating efficacy and safety of the hedgehog pathway inhibitor (HPI) vismodegib (GDC-0449) in patients with locally advanced (la) or metastatic (m) basal cell carcinoma (BCC)

Melanoma Research ◽

10.1097/01.cmr.0000399448.65869.b7 ◽

2011 ◽

Vol 21 ◽

pp. e9 ◽

Cited By ~ 8

Author(s):

A. Sekulic ◽

M.R. Migden ◽

A.E. Oro ◽

L. Dirix ◽

K. Lewis ◽

...

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Locally Advanced ◽

Hedgehog Pathway ◽

Efficacy And Safety ◽

Pivotal Study ◽

Hedgehog Pathway Inhibitor

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Acquired resistance to the Hedgehog pathway inhibitor vismodegib due to smoothened mutations in treatment of locally advanced basal cell carcinoma

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2014.08.001 ◽

2014 ◽

Vol 71 (5) ◽

pp. 1005-1008 ◽

Cited By ~ 41

Author(s):

Tjinta Brinkhuizen ◽

Marie G. Reinders ◽

Michel van Geel ◽

Annelot J.L. Hendriksen ◽

Aimée D.C. Paulussen ◽

...

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Locally Advanced ◽

Acquired Resistance ◽

Hedgehog Pathway ◽

Hedgehog Pathway Inhibitor ◽

Advanced Basal Cell Carcinoma

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Letter to the editor: Effective treatment of locally advanced periocular basal cell carcinoma with oral hedgehog pathway inhibitor

Graefe s Archive for Clinical and Experimental Ophthalmology ◽

10.1007/s00417-021-05310-0 ◽

2021 ◽

Author(s):

Nilay Yuksel

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Effective Treatment ◽

Basal Cell ◽

Locally Advanced ◽

Hedgehog Pathway ◽

Letter To The Editor ◽

Hedgehog Pathway Inhibitor

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The use of Hedgehog pathway inhibitors for locally advanced and metastatic basal cell carcinoma

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2018.05.1160 ◽

2018 ◽

Vol 79 (3) ◽

pp. AB294

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Locally Advanced ◽

Hedgehog Pathway ◽

Metastatic Basal Cell Carcinoma

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Practical management of the adverse effects of Hedgehog pathway inhibitor therapy for basal cell carcinoma

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2016.04.063 ◽

2017 ◽

Vol 76 (4) ◽

pp. 767-768 ◽

Cited By ~ 5

Author(s):

Audrey A. Jacobsen ◽

Andre R. Kydd ◽

John Strasswimmer

Keyword(s):

Basal Cell Carcinoma ◽

Adverse Effects ◽

Cell Carcinoma ◽

Basal Cell ◽

Inhibitor Therapy ◽

Hedgehog Pathway ◽

Practical Management ◽

Hedgehog Pathway Inhibitor

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