Positron Emission Tomography–Computed Tomography Imaging, Genomic Profile, and Survival in Patients With Head and Neck Cancer Receiving Immunotherapy

Author(s):  
Conall W. R. Fitzgerald ◽  
Cristina Valero ◽  
Christina E. Swartzwelder ◽  
Luc G. T. Morris
2015 ◽  
Vol 129 (9) ◽  
pp. 898-902 ◽  
Author(s):  
S P Williams ◽  
A J Kinshuck ◽  
C Williams ◽  
R Dwivedi ◽  
H Wieshmann ◽  
...  

AbstractObjective:The overlapping risk factors for lung and head and neck cancer present a definite risk of synchronous malignant pathology. This is the first study to specifically review incidental positron emission tomography computed tomography findings in the head and neck region in lung carcinoma patients.Methods:A retrospective review was performed of all lung cancer patients who underwent positron emission tomography computed tomography imaging over a five-year period (January 2008 – December 2012), identified from the Liverpool thoracic multidisciplinary team database.Results:Six hundred and nine patients underwent positron emission tomography computed tomography imaging over this period. In 76 (12.5 per cent) scans, incidental regions of avid18F-fluoro-deoxy-glucose uptake were reported in the head and neck region. In the 28 patients who were fully investigated, there were 4 incidental findings of malignancy.Conclusion:In lung cancer patients undergoing investigative positron emission tomography computed tomography scanning, a significant number will also present with areas of clinically significant18F-fluoro-deoxy-glucose uptake in the head and neck region. Of these, at least 5 per cent may have an undiagnosed malignancy.


2011 ◽  
Vol 120 (9) ◽  
pp. 593-602 ◽  
Author(s):  
Emma C. Cashman ◽  
Peter J. MacMahon ◽  
Martin J. Shelly ◽  
Eoin C. Kavanagh

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