Experimental Design in Method Optimization and Robustness Testing

Chemometric Methods in Capillary Electrophoresis ◽

10.1002/9780470530191.ch2 ◽

2009 ◽

pp. 11-74 ◽

Author(s):

Bieke Dejaegher ◽

Alexandra Durand ◽

Yvan Vander Heyden

Keyword(s):

Experimental Design ◽

Robustness Testing ◽

Method Optimization

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Validation and Experimental Design Assisted Robustness Testing of RPLC Method for the Simultaneous Analysis of Brinzolamide and Brimonidine Tartrate in an Ophthalmic Dosage Form

Indian Journal of Pharmaceutical Sciences ◽

10.4172/pharmaceutical-sciences.1000162 ◽

2016 ◽

Vol 78 (5) ◽

Author(s):

J R Christian ◽

Kalpana G Patel ◽

T R Gandhi

Keyword(s):

Experimental Design ◽

Dosage Form ◽

Simultaneous Analysis ◽

Robustness Testing ◽

Brimonidine Tartrate

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Robustness testing, using experimental design, of a flow-through dissolution method for a product where the actives have markedly differing solubility properties

International Journal of Pharmaceutics ◽

10.1016/s0378-5173(00)00509-3 ◽

2000 ◽

Vol 206 (1-2) ◽

pp. 55-61 ◽

Author(s):

M.S Bloomfield ◽

W.C Butler

Keyword(s):

Experimental Design ◽

Dissolution Method ◽

Robustness Testing ◽

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Robustness Testing in HPLC Analysis of Clarithromycin, Norfloxacin, Doxycycline, Tinidazole and Omeprazole in Pharmaceutical Dosage forms Using Experimental Design

Current Pharmaceutical Analysis ◽

10.2174/157341291001140102111733 ◽

2014 ◽

Vol 10 (1) ◽

pp. 58-70 ◽

Author(s):

Mahmoud Elkhoudary ◽

Randa Salam ◽

Ghada Hadad

Keyword(s):

Experimental Design ◽

Hplc Analysis ◽

Dosage Forms ◽

Pharmaceutical Dosage Forms ◽

Robustness Testing

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EXPERIMENTAL DESIGN STRATEGIES IN LC METHOD DEVELOPMENT AND IN ROBUSTNESS TESTING FOR REVERSIBLE CHOLINESTERASE INHIBITOR RIVASTIGMINE IN PHARMACEUTICAL FORMULATION

Journal of Liquid Chromatography &amp Related Technologies ◽

10.1080/10826070903439317 ◽

2009 ◽

Vol 33 (2) ◽

pp. 191-201 ◽

Author(s):

Mohammad H. Semreen ◽

Hassan Y. Aboul-Enein

Keyword(s):

Experimental Design ◽

Cholinesterase Inhibitor ◽

Method Development ◽

Pharmaceutical Formulation ◽

Design Strategies ◽

Robustness Testing

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Preparation of CaP/pDNA nanoparticles by reverse micro-emulsion method: Optimization of formulation variables using experimental design

Asian Journal of Pharmaceutical Sciences ◽

10.1016/j.ajps.2016.09.006 ◽

2017 ◽

Vol 12 (2) ◽

pp. 179-186 ◽

Author(s):

Wenpan Li ◽

Shasha Jing ◽

Xiu Xin ◽

Xirui Zhang ◽

Kang Chen ◽

...

Keyword(s):

Experimental Design ◽

Emulsion Method ◽

Micro Emulsion ◽

Method Optimization ◽

Formulation Variables

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Experimental design strategies in the optimization and robustness testing of adsorptive stripping voltammetric conditions for kynurenic acid determination

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/s0731-7085(96)02029-8 ◽

1997 ◽

Vol 15 (9-10) ◽

pp. 1585-1594 ◽

Author(s):

S. Furlanetto ◽

S. Pinzauti ◽

P. Gratteri ◽

E. La Porta ◽

G. Calzeroni

Keyword(s):

Experimental Design ◽

Kynurenic Acid ◽

Design Strategies ◽

Robustness Testing ◽

Acid Determination

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The use of the Box–Behnken experimental design in the optimisation and robustness testing of a capillary electrophoresis method for the analysis of ethambutol hydrochloride in a pharmaceutical formulation

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/s0731-7085(01)00659-8 ◽

2002 ◽

Vol 27 (6) ◽

pp. 995-1007 ◽

Author(s):

R Ragonese ◽

M Macka ◽

J Hughes ◽

P Petocz

Keyword(s):

Capillary Electrophoresis ◽

Experimental Design ◽

Pharmaceutical Formulation ◽

Robustness Testing ◽

Capillary Electrophoresis Method ◽

Electrophoresis Method

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Chiral separation of tramadol enantiomers by capillary electrophoresis using cyclodextrins as chiral selectors and experimental design method optimization

Chemical Papers ◽

10.1007/s11696-019-00789-8 ◽

2019 ◽

Vol 73 (9) ◽

pp. 2363-2370 ◽

Author(s):

Anita Sarkany ◽

Gabriel Hancu ◽

Anca Cârje ◽

Claudiu Drăguț ◽

Lajos Attila Papp

Keyword(s):

Capillary Electrophoresis ◽

Experimental Design ◽

Chiral Separation ◽

Design Method ◽

Chiral Selectors ◽

Experimental Design Method ◽

Method Optimization

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Application of experimental design in HPLC method optimization and robustness for the simultaneous determination of Canagliflozin, Empagliflozin, Linagliptin and Metformin in tablet

Biomedical Chromatography ◽

10.1002/bmc.5155 ◽

2021 ◽

Author(s):

Bahia Abbas Moussa ◽

Marianne Alphonse Mahrouse ◽

Michael Gamal Fawzy

Keyword(s):

Experimental Design ◽

Simultaneous Determination ◽

Hplc Method ◽

Method Optimization

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Determination of homogentisic acid in urine for diagnosis of alcaptonuria: Capillary electrophoretic method optimization using experimental design

Biomedical Chromatography ◽

10.1002/bmc.4216 ◽

2018 ◽

Vol 32 (7) ◽

pp. e4216 ◽

Author(s):

Nevin Öztekin ◽

Gülfem S. Balta ◽

M. Şerif Cansever

Keyword(s):

Experimental Design ◽

Homogentisic Acid ◽

Electrophoretic Method ◽

Method Optimization ◽

Capillary Electrophoretic

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