The Effects of Biological Data Collection in Longitudinal Surveys on Subsequent Wave Cooperation

Author(s):  
Fiona Pashazadeh ◽  
Alexandru Cernat ◽  
Joseph W. Sakshaug
2017 ◽  
Vol 33 (3) ◽  
pp. 601-624
Author(s):  
Taylor Lewis

AbstractTo mitigate the potentially harmful effects of nonresponse, most surveys repeatedly follow up with nonrespondents, often targeting a response rate or predetermined number of completes. Each additional recruitment attempt generally brings in a new wave of data, but returns gradually diminish over the course of a fixed data collection protocol, as each subsequent wave tends to consist of fewer responses than the last. Consequently, point estimates begin to stabilize. This is the notion of phase capacity, suggesting some form of design change is in order, such as switching modes, increasing the incentive, or, as is considered exclusively in this research, discontinuing the nonrespondent follow-up campaign altogether. A previously proposed test for phase capacity calls for multiply imputing nonrespondents’ missing data to assess, retrospectively, whether the most recent wave of data significantly altered a key, nonresponse-adjusted point estimate. This study introduces a more flexible adaptation amenable to surveys that instead reweight the observed data to compensate for nonresponse. Results from a simulation study and application indicate that, all else equal, the weighting version of the test is more sensitive to point estimate changes, thereby dictating more follow-up attempts are warranted.


2019 ◽  
Author(s):  
Talima Pearson ◽  
Steven D Barger ◽  
Monica Lininger ◽  
Heidi Wayment ◽  
Crystal Hepp ◽  
...  

BACKGROUND Health care–associated <italic>Staphylococcus aureus</italic> infections are declining but remain common. Conversely, rates of community-associated infections have not decreased because of the inadequacy of public health mechanisms to control transmission in a community setting. Our long-term goal is to use risk-based information from empirical socio-cultural-biological evidence of carriage and transmission to inform intervention strategies that reduce <italic>S aureus</italic> transmission in the community. Broad differences in social interactions because of cultural affiliation, travel, and residency patterns may impact <italic>S aureus</italic> carriage and transmission, either as risk or as protective factors. OBJECTIVE This study aims to (1) characterize <italic>S aureus</italic> carriage rates and compare circulating pathogen genotypes with those associated with disease isolated from local clinical specimens across resident groups and across Hispanic and non-Hispanic white ethnic groups and (2) evaluate social network relationships and social determinants of health-based risk factors for their impact on carriage and transmission of <italic>S aureus</italic>. METHODS We combine sociocultural survey approaches to population health sampling with <italic>S aureus</italic> carriage and pathogen genomic analysis to infer transmission patterns. Whole genome sequences of <italic>S aureus</italic> from community and clinical sampling will be phylogenetically compared to determine if strains that cause disease (clinical samples) are representative of community genotypes. Phylogenetic comparisons of strains collected from participants within social groups can indicate possible transmission within the group. We can therefore combine transmission data with social determinants of health variables (socioeconomic status, health history, etc) and social network variables (both egocentric and relational) to determine the extent to which social relationships are associated with <italic>S aureus</italic> transmission. RESULTS We conducted a first year pilot test and feasibility test of survey and biological data collection and analytic procedures based on the original funded design for this project (#NIH U54MD012388). That design resulted in survey data collection from 336 groups and 1337 individuals. The protocol, described below, is a revision based on data assessment, new findings for statistical power analyses, and refined data monitoring procedures. CONCLUSIONS This study is designed to evaluate ethnic-specific prevalence of <italic>S aureus</italic> carriage in a US border community. The study will also examine the extent to which kin and nonkin social relationships are concordant with carriage prevalence in social groups. Genetic analysis of <italic>S aureus</italic> strains will further distinguish putative transmission pathways across social relationship contexts and inform our understanding of the correspondence of <italic>S aureus</italic> reservoirs across clinical and community settings. Basic community-engaged nonprobabilistic sampling procedures provide a rigorous framework for completion of this 5-year study of the social and cultural parameters of <italic>S aureus</italic> carriage and transmission.


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