The mechanism of action of T-705 as a unique delayed chain terminator on influenza viral polymerase transcription

2021 ◽  
pp. 106652
Author(s):  
Yuqing Wang ◽  
Congmin Yuan ◽  
Xinzhou Xu ◽  
Tin Hang Chong ◽  
Lu Zhang ◽  
...  
Keyword(s):  
Mechanism Of Action ◽  
Viral Polymerase ◽  
Chain Terminator

Optimization of Polydimethylsiloxane Synthesized Parameters as Vitreous Humour Substitutes

2019 ◽  
Vol 966 ◽  
pp. 189-193 ◽  
Author(s):  
Soni Setiadji ◽  
Fitrilawati ◽  
Anna Niska Fauza ◽  
Atikah Ardi ◽  
Ressa Muhrifah Novianti ◽  
...  
Keyword(s):  
Reaction Time ◽  
Ring Opening ◽  
Vitreoretinal Surgery ◽  
Ring Opening Polymerization ◽  
Vitreous Humour ◽  
Commercial Product ◽  
Chain Terminator

Polydimethylsiloxane (PDMS) with two type viscosity that commonly used as vitreous humour substitutes in vitreoretinal surgery has been successfully synthesized by ring-opening polymerization. Optimization of synthesized parameters such as ratio of monomer and chain terminator, the amount of initiator, mixing temperature and reaction time was carried out to obtain PDMS materials having similar properties with commercial product. PDMS with viscosity of 1.17 Pas that very close to viscosity of commercial PDMS of 1.08 Pas, was successfully synthesized with a ratio of 26:10 monomer and terminator chain, 0.58 M of initiator KOH, 170 oC of mixing temperature and 35 minutes of reaction time. By changing reaction time to 40 minutes, PDMS was successfully synthesized with viscosity of 3.42 that similar to that of commercial one.

scholarly journals Characterization of a novel type of chain-terminator Galbeta1-6Galbeta1-4)GlcNAc in an oligosaccharide related to N-glycosylated protein glycans isolated from GM1 the urine of patients with gangliosidosis

1991 ◽  
Vol 198 (2) ◽  
pp. 521-526 ◽  
Author(s):  
Jean Claude MICHALSKI ◽  
Jerome LEMOINE ◽  
Jean Michel WIERUSZESKI ◽  
Bernard FOURNET ◽  
Jean MONTREUIL ◽  
...  
Keyword(s):  
Chain Terminator

Increased sensitivity for detection of carcinogen-induced DNA repair with the chain terminator dideoxythymidine

1978 ◽  
Vol 83 (4) ◽  
pp. 1538-1544 ◽  
Author(s):  
Gary J. Smith ◽  
Ronald K. Charlton ◽  
Joe W. Grisham ◽  
David G. Kaufman
Keyword(s):  
Dna Repair ◽  
Increased Sensitivity ◽  
Chain Terminator

An HIV Reverse Transcriptase-Selective Nucleoside Chain Terminator

2003 ◽  
Vol 125 (3) ◽  
pp. 616-617 ◽  
Author(s):  
Andrew W. Fraley ◽  
Dongli Chen ◽  
Kenneth Johnson ◽  
Larry W. McLaughlin
Keyword(s):  
Reverse Transcriptase ◽  
Hiv Reverse Transcriptase ◽  
Chain Terminator

scholarly journals Synthesis of controlled polymeric cross-linked coatings via iniferter polymerisation in the presence of tetraethyl thiuram disulphide chain terminator

2010 ◽  
Vol 25 (9) ◽  
pp. 2149-2155 ◽  
Author(s):  
A. Bossi ◽  
M.J. Whitcombe ◽  
Y. Uludag ◽  
S. Fowler ◽  
I. Chianella ◽  
...  
Keyword(s):  
Chain Terminator

Canonical 3′-deoxyribonucleotides as a chain terminator for HCV NS5B RNA-dependent RNA polymerase

2003 ◽  
Vol 58 (3) ◽  
pp. 243-251 ◽  
Author(s):  
Jaehoon Shim ◽  
Gabry Larson ◽  
Vicky Lai ◽  
Suhaila Naim ◽  
Jim Zhen Wu
Keyword(s):  
Rna Polymerase ◽  
Rna Dependent Rna Polymerase ◽  
A Chain ◽  
Hcv Ns5b ◽  
Chain Terminator
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