Prevalence of neuropsychiatric lupus in psychosis patients with a positive antinuclear antibody

Rowell’s syndrome is a rare disorder characterised by an association of lupus erythematosus with erythema multiforme (EM)-like skin lesions. EM as the initial clinical presentation of systemic lupus erythematosus is also atypical and even rarer. We report the case of an 18-year-old girl admitted to our hospital with fever and polyarthralgia along with multiple discrete ill-defined target lesions with crust formation over forehead, cheek, external ears, scalp, upper chest and back (predominantly over sun-exposed areas) with ulceration over hard palate. Investigations revealed pancytopaenia, a positive rheumatoid factor, positive antinuclear antibody with a speckled pattern, anti-Smith antibody and strongly positive anti-Ro. Patient was diagnosed with Rowell’s syndrome as per clinical and laboratory features. Majority of skin lesions including oral ulcerations subsided gradually after treatment with steroids and hydroxychloroquine.

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Classic Triad of Ross Syndrome with Diffuse Autonomic Dysfunction and Positive Antinuclear Antibody Titre

Neuro-Ophthalmology ◽

10.3109/01658107.2012.704653 ◽

2012 ◽

Vol 36 (4) ◽

pp. 138-142 ◽

Cited By ~ 1

Author(s):

Osama H. Ababneh ◽

Ala’ A. Khamees ◽

Sawsan M. Kh. Qiblawi

Keyword(s):

Antibody Titre ◽

Autonomic Dysfunction ◽

Antinuclear Antibody ◽

Positive Antinuclear Antibody ◽

Classic Triad

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Antinuclear antibody determinations in Ro(SSA)-positive, antinuclear antibody—negative lupus and Sjögren's syndrome patients

Journal of the American Academy of Dermatology ◽

10.1016/s0190-9622(83)70065-4 ◽

1983 ◽

Vol 8 (5) ◽

pp. 611-615 ◽

Cited By ~ 9

Author(s):

Normand Doré ◽

Daniel Synkowski ◽

Thomas T. Provost

Keyword(s):

Sjögren’S Syndrome ◽

Antinuclear Antibody ◽

Sjögren's Syndrome ◽

Sjogren’S Syndrome ◽

Sjogren's Syndrome ◽

Positive Antinuclear Antibody ◽

Sjögren‘S Syndrome

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Autoinflammatory/Autoimmunity Syndrome Induced By Adjuvants (ASIA) Due to Silicone Incompatibility Syndrome

Case Reports in Rheumatology ◽

10.1155/2021/5595739 ◽

2021 ◽

Vol 2021 ◽

pp. 1-4

Author(s):

Genessis Maldonado ◽

Roberto Guerrero ◽

Maria Intriago ◽

Carlos Rios

Keyword(s):

Hyaluronic Acid ◽

Antinuclear Antibody ◽

Liquid Paraffin ◽

Adaptive Immune System ◽

Chemical Compounds ◽

Anticentromere Antibody ◽

Adaptive Immune ◽

Breast Prosthesis ◽

Autoimmune Syndrome ◽

Positive Antinuclear Antibody

The adjuvant-induced autoimmune syndrome (ASIA) is associated with a dysregulation of the innate and adaptive immune system after exposure to chemical compounds, including liquid paraffin, silicone gel, acrylamides, and hyaluronic acid. Due the increase of the use of these compounds in cosmetic procedures, the prevalence of this syndrome is increasing. We present the first report in Ecuador associated to ASIA after an elective silicone breast prosthesis procedure, manifested as polyarthralgia, positive antinuclear antibody, anticentromere antibody, and a moderate positive Sclero-70.

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Pyoderma Gangrenosum with Positive Antinuclear Antibody, in the Absence of Systemic Association

Nepal Journal of Dermatology Venereology & Leprology ◽

10.3126/njdvl.v16i1.19418 ◽

2018 ◽

Vol 16 (1) ◽

pp. 66-69

Author(s):

Smriti Shrestha ◽

Alisha Aryal

Keyword(s):

Pyoderma Gangrenosum ◽

Lupus Erythematosus ◽

Antinuclear Antibody ◽

Case Reports ◽

Neutrophilic Dermatosis ◽

Systemic Diseases ◽

Connective Tissue Disorders ◽

Systemic Lupus ◽

Unique Case ◽

Positive Antinuclear Antibody

Pyoderma gangrenosum is an uncommon neutrophilic dermatosis, seen on legs, and infrequently on hands and other anatomical sites. It is associated with systemic diseases in 50-70% of the cases. Antinuclear antibody (ANA) seropositivity has been reported in pyoderma gangrenosum associated with connective tissue disorders. However, there are very few case reports of pyoderma gangrenosum in patients of systemic lupus erythematosus, while we did not find any reports of ANA seropositivity in isolated pyoderma gangrenosum. Hence, we report this unique case of pyoderma gangrenosum with classical clinicohistopathology, positive ANA but no systemic association. As anticipated, our patient responded promptly to steroids.

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