Ex Vivo Human Trabecular Bone Model for Biocompatibility Evaluation of Calcium Phosphate Composites Modified with Spray Dried Biodegradable Microspheres

2013 ◽  
Vol 2 (10) ◽  
pp. 1361-1369 ◽  
Author(s):  
Julia Schnieders ◽  
Uwe Gbureck ◽  
Oliver Germershaus ◽  
Marita Kratz ◽  
David B. Jones ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Trabecular Bone ◽  
Ex Vivo ◽  
Biodegradable Microspheres ◽  
Bone Model ◽  
Human Trabecular Bone ◽  
Spray Dried

Age-related changes in resorption cavity characteristics in human trabecular bone

1991 ◽  
Vol 1 (4) ◽  
pp. 257-261 ◽  
Author(s):  
P. I. Croucher ◽  
N. J. Garrahan ◽  
R. W. E. Mellish ◽  
Juliette E. Compston
Keyword(s):  
Trabecular Bone ◽  
Human Trabecular Bone ◽  
Age Related ◽  
Cavity Characteristics ◽  
Age Related Changes

scholarly journals Biaxial Normal Strength Behavior in the Axial-Transverse Plane for Human Trabecular Bone—Effects of Bone Volume Fraction, Microarchitecture, and Anisotropy

2013 ◽  
Vol 135 (12) ◽  
Author(s):  
Arnav Sanyal ◽  
Tony M. Keaveny
Keyword(s):  
Trabecular Bone ◽  
Volume Fraction ◽  
Elastic Anisotropy ◽  
Bone Volume ◽  
Transverse Plane ◽  
Mechanical Anisotropy ◽  
Bone Volume Fraction ◽  
Human Trabecular Bone ◽  
Strength Behavior ◽  
Normal Strength

The biaxial failure behavior of the human trabecular bone, which has potential relevance both for fall and gait loading conditions, is not well understood, particularly for low-density bone, which can display considerable mechanical anisotropy. Addressing this issue, we investigated the biaxial normal strength behavior and the underlying failure mechanisms for human trabecular bone displaying a wide range of bone volume fraction (0.06–0.34) and elastic anisotropy. Micro-computed tomography (CT)-based nonlinear finite element analysis was used to simulate biaxial failure in 15 specimens (5 mm cubes), spanning the complete biaxial normal stress failure space in the axial-transverse plane. The specimens, treated as approximately transversely isotropic, were loaded in the principal material orientation. We found that the biaxial stress yield surface was well characterized by the superposition of two ellipses—one each for yield failure in the longitudinal and transverse loading directions—and the size, shape, and orientation of which depended on bone volume fraction and elastic anisotropy. However, when normalized by the uniaxial tensile and compressive strengths in the longitudinal and transverse directions, all of which depended on bone volume fraction, microarchitecture, and mechanical anisotropy, the resulting normalized biaxial strength behavior was well described by a single pair of (longitudinal and transverse) ellipses, with little interspecimen variation. Taken together, these results indicate that the role of bone volume fraction, microarchitecture, and mechanical anisotropy is mostly accounted for in determining the uniaxial strength behavior and the effect of these parameters on the axial-transverse biaxial normal strength behavior per se is minor.

scholarly journals Development of a Crushable Foam Model for Human Trabecular Bone

2021 ◽  
Author(s):  
Navid Soltanihafshejani ◽  
Thom Bitter ◽  
Dennis Janssen ◽  
Nico Verdonschot
Keyword(s):  
Trabecular Bone ◽  
Human Trabecular Bone ◽  
Foam Model

TEM analysis of the nanostructure of normal and osteoporotic human trabecular bone

Bone ◽  
2003 ◽  
Vol 33 (3) ◽  
pp. 270-282 ◽  
Author(s):  
Matthew A Rubin ◽  
Iwona Jasiuk ◽  
Jeannette Taylor ◽  
Janet Rubin ◽  
Timothy Ganey ◽  
...  
Keyword(s):  
Trabecular Bone ◽  
Tem Analysis ◽  
Human Trabecular Bone

Energy-dispersive X-ray microanalysis of the bone mineral content in human trabecular bone: A comparison with ICPES and neutron activation analysis

1994 ◽  
Vol 55 (3) ◽  
pp. 236-239 ◽  
Author(s):  
K. Åkesson ◽  
M. D. Grynpas ◽  
R. G. V. Hancock ◽  
R. Odselius ◽  
K. J. Obrant
Keyword(s):  
Neutron Activation Analysis ◽  
Activation Analysis ◽  
Neutron Activation ◽  
Bone Mineral Content ◽  
Trabecular Bone ◽  
Bone Mineral ◽  
Mineral Content ◽  
Energy Dispersive ◽  
X Ray ◽  
Human Trabecular Bone

scholarly journals Human ex vivo 3D bone model recapitulates osteocyte response to metastatic prostate cancer

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Saba Choudhary ◽  
Poornema Ramasundaram ◽  
Eugenia Dziopa ◽  
Ciaran Mannion ◽  
Yair Kissin ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Metastatic Prostate Cancer ◽  
Ex Vivo ◽  
Bone Model

Micromechanical properties of human trabecular bone: A hierarchical investigation using nanoindentation

2008 ◽  
Vol 87A (1) ◽  
pp. 196-202 ◽  
Author(s):  
Jonathan Norman ◽  
Joe G. Shapter ◽  
Ken Short ◽  
Lachlan J. Smith ◽  
Nicola L. Fazzalari
Keyword(s):  
Trabecular Bone ◽  
Human Trabecular Bone ◽  
Micromechanical Properties

Mechanical Evaluation of Fixation of Titanium Implants in Trabecular Bone Using an Injectable Calcium Phosphate Cement

2001 ◽  
Vol 218-220 ◽  
pp. 361-362
Author(s):  
E.M. Ooms ◽  
Joop G.C. Wolke ◽  
John J. Jansen
Keyword(s):  
Calcium Phosphate ◽  
Trabecular Bone ◽  
Calcium Phosphate Cement ◽  
Titanium Implants
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