Catalytic Asymmetric Mannich‐Type Reaction of Malononitrile with N‐Boc α‐Ketiminoesters Using Chiral Organic Base Catalyst with Halogen Bond Donor Functionality

2020 ◽  
Vol 362 (8) ◽  
pp. 1674-1678 ◽  
Author(s):  
Satoru Kuwano ◽  
Yuki Nishida ◽  
Takumi Suzuki ◽  
Takayoshi Arai
Keyword(s):  
Halogen Bond ◽  
Organic Base ◽  
Base Catalyst ◽  
Type Reaction ◽  
Catalytic Asymmetric

Enantio- and Diastereoselective Double Mannich Reaction of Malononitrile with N-Boc Imines Using Bifunctional Organoiodine Catalyst

2021 ◽  
Author(s):  
Satoru Kuwano ◽  
Eri Ogino ◽  
Takayoshi Arai
Keyword(s):  
Mannich Reaction ◽  
Halogen Bond ◽  
Organic Base ◽  
Base Catalyst

A chiral organic base catalyst with halogen bond donor functionality was used to catalyze the asymmetric double Mannich reaction of malononitrile with N-Boc imines to afford 1,3-diamine derivatives in excellent...

Catalytic Asymmetric Three-Component Mannich-Type Reaction of Alkenyl Trichloroacetates

2009 ◽  
Vol 11 (22) ◽  
pp. 5310-5313 ◽  
Author(s):  
Atsuto Izumiseki ◽  
Kazuhiro Yoshida ◽  
Akira Yanagisawa
Keyword(s):  
Type Reaction ◽  
Catalytic Asymmetric

A Catalytic Asymmetric Strecker-Type Reaction: Interesting Reactivity Difference between TMSCN and HCN

2000 ◽  
Vol 112 (9) ◽  
pp. 1716-1718 ◽  
Author(s):  
Masahiro Takamura ◽  
Yoshitaka Hamashima ◽  
Hiroyuki Usuda ◽  
Motomu Kanai ◽  
Masakatsu Shibasaki
Keyword(s):  
Type Reaction ◽  
Catalytic Asymmetric

scholarly journals Direct Catalytic Asymmetric Mannich-Type Reaction of an α-CF3 Amide to Isatin Imines

Synlett ◽  
2018 ◽  
Vol 30 (04) ◽  
pp. 488-492 ◽  
Author(s):  
Jin-Sheng Yu ◽  
Hidetoshi Noda ◽  
Naoya Kumagai ◽  
Masakatsu Shibasaki
Keyword(s):  
Lewis Acid ◽  
Tertiary Amine ◽  
Chiral Center ◽  
Chiral Catalyst ◽  
Type Reaction ◽  
One Step ◽  
Catalytic Asymmetric ◽  
Chiral Bisphosphine Ligand

An α-CF3 amide underwent direct asymmetric Mannich-type reaction to isatin imines in the presence of a chiral catalyst comprising a soft Lewis acid Cu(I), a chiral bisphosphine ligand, and Barton’s base. The Mannich adduct was converted in one step into a unique tricycle bearing a trifluoromethylated chiral center and an α-tertiary amine moiety.

Direct Catalytic Asymmetric Mannich-Type Reaction of α- and β-Fluorinated Amides

2015 ◽  
Vol 137 (50) ◽  
pp. 15929-15939 ◽  
Author(s):  
Lennart Brewitz ◽  
Fernando Arteaga Arteaga ◽  
Liang Yin ◽  
Kaliyamoorthy Alagiri ◽  
Naoya Kumagai ◽  
...  
Keyword(s):  
Type Reaction ◽  
Catalytic Asymmetric

ChemInform Abstract: A Catalytic Asymmetric Ugi-Type Reaction with Acyclic Azomethine Imines.

ChemInform ◽  
2013 ◽  
Vol 44 (1) ◽  
pp. no-no
Author(s):  
Takuya Hashimoto ◽  
Hidenori Kimura ◽  
Yu Kawamata ◽  
Keiji Maruoka
Keyword(s):  
Type Reaction ◽  
Azomethine Imines ◽  
Catalytic Asymmetric

ChemInform Abstract: Catalytic Asymmetric Mannich-Type Reaction of N-Alkylidene-α-aminoacetonitrile with Ketimines.

ChemInform ◽  
2015 ◽  
Vol 46 (34) ◽  
pp. no-no
Author(s):  
Shaoquan Lin ◽  
Yuji Kawato ◽  
Naoya Kumagai ◽  
Masakatsu Shibasaki
Keyword(s):  
Type Reaction ◽  
Catalytic Asymmetric
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