Chiral Ammonium Betaines: A Bifunctional Organic Base Catalyst for Asymmetric Mannich-Type Reaction of α-Nitrocarboxylates

2008 ◽  
Vol 130 (33) ◽  
pp. 10878-10879 ◽  
Author(s):  
Daisuke Uraguchi ◽  
Kyohei Koshimoto ◽  
Takashi Ooi
Keyword(s):  
Organic Base ◽  
Base Catalyst ◽  
Type Reaction

The preparation of carbon aerogels based upon the gelation of resorcinol–furfural in isopropanol with organic base catalyst

2004 ◽  
Vol 336 (1) ◽  
pp. 26-31 ◽  
Author(s):  
Dingcai Wu ◽  
Ruowen Fu ◽  
Shuting Zhang ◽  
Mildred S Dresselhaus ◽  
Gene Dresselhaus
Keyword(s):  
Carbon Aerogels ◽  
Organic Base ◽  
Base Catalyst

Mild Organic Base-Catalyzed Primary Alcohol-Selective Aroylation Reaction Using N-Aroylcarbazoles for Underexplored Prodrugs

2020 ◽  
Author(s):  
Yasuaki Morita ◽  
Bubwoong Kang ◽  
Rubi Nakashima ◽  
Yuki Shimizu ◽  
Asumi Sakai ◽  
...  
Keyword(s):  
Primary Alcohol ◽  
Reaction System ◽  
Organic Base ◽  
Base Catalyst ◽  
Preparation Methods ◽  
General Base ◽  
Drug Molecules ◽  
Synthetic Utility ◽  
Scale Preparation ◽  
Complex Drug

<div>We report a highly primary alcohol-selective aroylation reaction using N-aroylcarbazoles (NAroCs). The aroylation</div><div>proceeded smoothly in the presence of DBU, which most likely works as a general base catalyst in the reaction system. The synthetic utility was displayed in the primary alcohol-selective aroylation of complex drug molecules and natural products to their prodrugs. Stoichiometrically generated carbazole, the starting material of NAroCs could be easily recovered. We also established safer multigram and multidecagram scale preparation methods of NAroCs, which are easy-to-handle bench-stable reagents.</div>

Degradation of anhydride-cured epoxy resin using simultaneously recyclable solvent and organic base catalyst

2017 ◽  
Vol 20 (1) ◽  
pp. 568-577 ◽  
Author(s):  
Lipeng Zhang ◽  
Jie Liu ◽  
Weidong Nie ◽  
Kai Wang ◽  
Yanhui Wang ◽  
...  
Keyword(s):  
Epoxy Resin ◽  
Organic Base ◽  
Base Catalyst

Kolbe–Schmitt type reaction under ambient conditions mediated by an organic base

2019 ◽  
Vol 55 (66) ◽  
pp. 9837-9840 ◽  
Author(s):  
Yuta Sadamitsu ◽  
Akira Okumura ◽  
Kodai Saito ◽  
Tohru Yamada
Keyword(s):  
Carbon Dioxide ◽  
Organic Base ◽  
Ambient Conditions ◽  
Type Reaction ◽  
Combined Use

The combined use of carbon dioxide and an organic base for resorcinols realized a Kolbe–Schmitt type reaction under ambient conditions.

A chiral organic base catalyst with halogen-bonding-donor functionality: asymmetric Mannich reactions of malononitrile with N-Boc aldimines and ketimines

2018 ◽  
Vol 54 (31) ◽  
pp. 3847-3850 ◽  
Author(s):  
Satoru Kuwano ◽  
Takumi Suzuki ◽  
Yusei Hosaka ◽  
Takayoshi Arai
Keyword(s):  
Halogen Bonding ◽  
Organic Base ◽  
Base Catalyst ◽  
Mannich Reactions

Asymmetric Mannich reactions of malononitrile with various N-Boc imines were developed using a chiral organic base catalyst with halogen-bonding-donor functionality.

Enantio- and Diastereoselective Double Mannich Reaction of Malononitrile with N-Boc Imines Using Bifunctional Organoiodine Catalyst

2021 ◽  
Author(s):  
Satoru Kuwano ◽  
Eri Ogino ◽  
Takayoshi Arai
Keyword(s):  
Mannich Reaction ◽  
Halogen Bond ◽  
Organic Base ◽  
Base Catalyst

A chiral organic base catalyst with halogen bond donor functionality was used to catalyze the asymmetric double Mannich reaction of malononitrile with N-Boc imines to afford 1,3-diamine derivatives in excellent...

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