scholarly journals A Lubricated Nonimmunogenic Neural Probe for Acute Insertion Trauma Minimization and Long‐Term Signal Recording

2021 ◽  
pp. 2100231
Author(s):  
Yeontaek Lee ◽  
Hyogeun Shin ◽  
Dongwon Lee ◽  
Sungah Choi ◽  
Il‐Joo Cho ◽  
...  
2021 ◽  
Vol 8 (15) ◽  
pp. 2170095
Author(s):  
Yeontaek Lee ◽  
Hyogeun Shin ◽  
Dongwon Lee ◽  
Sungah Choi ◽  
Il‐Joo Cho ◽  
...  

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Surabhi Nimbalkar ◽  
Elisa Castagnola ◽  
Arvind Balasubramani ◽  
Alice Scarpellini ◽  
Soshi Samejima ◽  
...  
Keyword(s):  

2009 ◽  
Author(s):  
S. Lee ◽  
R. Kobayashi ◽  
S. Kanno ◽  
K. Lee ◽  
T. Fukushima ◽  
...  

2013 ◽  
Vol 740 ◽  
pp. 555-559 ◽  
Author(s):  
Rui Qi Lim ◽  
Kwan Ling Tan ◽  
Wei Guo Chen ◽  
Mink Yu Je ◽  
Tack Boon Yee ◽  
...  

This work presents a bio-degradable glass probes and its biocompatibility assessment for neural applications. The probes can be implanted into different sites of the human brain for recording and stimulating purposes. Current existing neural probe address the probe stiffness requirement for the penetration of brain tissue. However, this requirement normally resulted in the rigidity of the probe which is non-compatible with the brain tissue movement for long term implantation. The brain neuron cells will be damaged by too rigid probe substrate. In order to address this issue, bio-degradable glass probes having sufficient stiffness for a smooth brain insertion as well as ability to degrade after implantation; leaving behind the flexible circuitry substrate was being explored. The biodegradability of the proposed probe was evaluated.


1982 ◽  
Vol BME-29 (6) ◽  
pp. 393-403 ◽  
Author(s):  
Carlo J. De Luca ◽  
L. Donald Gilmore ◽  
L. Jack Bloom ◽  
Sandra J. Thomson ◽  
Allen L. Cudworth ◽  
...  
Keyword(s):  

2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.


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