scholarly journals Safety, efficacy, and operability of a newly developed absorbable adhesion barrier (GM142) in patients with primary rectal cancer scheduled for diverting ileostomy during laparoscopic surgery: Randomized controlled trial

2022 ◽  
Author(s):  
Jun Watanabe ◽  
Shigeki Yamaguchi ◽  
Ichiro Takemasa ◽  
Masayoshi Yasui ◽  
Yasumitsu Hirano ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Randomized Controlled Trial ◽  
Laparoscopic Surgery ◽  
Controlled Trial ◽  
Diverting Ileostomy ◽  
Adhesion Barrier ◽  
Randomized Controlled ◽  
Primary Rectal Cancer

Extralevator withvsnonextralevator abdominoperineal excision for rectal cancer: the RELAPe randomized controlled trial

2017 ◽  
Vol 19 (2) ◽  
pp. 148-157 ◽  
Author(s):  
F. Bianco ◽  
G. Romano ◽  
P. Tsarkov ◽  
G. Stanojevic ◽  
K. Shroyer ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Abdominoperineal Excision ◽  
Randomized Controlled

scholarly journals Spinal block and delirium in oncologic patients after laparoscopic surgery in the Trendelenburg position: A randomized controlled trial

PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0249808
Author(s):  
Jorge Kiyoshi Mitsunaga ◽  
Vinicius Fernando Calsavara ◽  
Elton Shinji Onari ◽  
Vinicius Monteiro Arantes ◽  
Carolina Paiva Akamine ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Laparoscopic Surgery ◽  
General Anesthesia ◽  
Controlled Trial ◽  
Spinal Block ◽  
Trendelenburg Position ◽  
General Anesthesia Group ◽  
Randomized Controlled ◽  
Anesthesia Group ◽  
Oncologic Patients

Delirium is the most common postsurgical neurological complication and has a variable incidence rate. Laparoscopic surgery, when associated with the Trendelenburg position, can cause innumerable physiological changes and increase the risk of neurocognitive changes. The association of general anesthesia with a spinal block allows the use of lower doses of anesthetic agents for anesthesia maintenance and facilitates better control over postoperative pain. Our primary outcome was to assess whether a spinal block influences the incidence of delirium in oncologic patients following laparoscopic surgery in the Trendelenburg position. Our secondary outcome was to analyze whether there were other associated factors. A total of 150 oncologic patients who underwent elective laparoscopic surgeries in the Trendelenburg position were included in this randomized controlled trial. The patients were randomized into 2 groups: the general anesthesia group and the general anesthesia plus spinal block group. Patients were immediately evaluated during the postoperative period and monitored until they were discharged, to rule out the presence of delirium. Delirium occurred in 29 patients in total (22.3%) (general anesthesia group: 30.8%; general anesthesia plus spinal block: 13.8% p = 0.035). Patients who received general anesthesia had a higher risk of delirium than patients who received general anesthesia associated with a spinal block (odds ratio = 3.4; 95% confidence interval: 1.2–9.6; p = 0.020). Spinal block was associated with reduced delirium incidence in oncologic patients who underwent elective laparoscopic surgeries in the Trendelenburg position.

Sign in / Sign up

Export Citation Format

Share Document