Transformation of chronic myelomonocytic leukemia to acute lymphoblastic leukemia: Case report and review of the literature of lymphoblastic transformation of myelodysplastic syndrome

1995 ◽  
Vol 49 (2) ◽  
pp. 157-162 ◽  
Author(s):  
Peter A. Kouides ◽  
John M. Bennett
Keyword(s):  
Case Report ◽  
Acute Lymphoblastic Leukemia ◽  
Myelodysplastic Syndrome ◽  
Lymphoblastic Leukemia ◽  
Chronic Myelomonocytic Leukemia ◽  
Review Of The Literature ◽  
Lymphoblastic Transformation ◽  
Myelomonocytic Leukemia

Transformation of Myelodysplastic Syndrome to Acute Lymphoblastic Leukemia: A Case Report and Review of the Literature

2004 ◽  
Vol 79 (2) ◽  
pp. 147-151 ◽  
Author(s):  
Norihide Sato ◽  
Tomonori Nakazato ◽  
Masahiro Kizaki ◽  
Yasuo Ikeda ◽  
Shinichiro Okamoto
Keyword(s):  
Case Report ◽  
Acute Lymphoblastic Leukemia ◽  
Myelodysplastic Syndrome ◽  
Lymphoblastic Leukemia ◽  
Review Of The Literature

scholarly journals A New Subtype of Pre-B Acute Lymphoblastic Leukemia With t(5; 12)(q31q33; p12), Molecularly and Cytogenetically Distinct From t(5; 12) in Chronic Myelomonocytic Leukemia

Blood ◽  
1997 ◽  
Vol 89 (5) ◽  
pp. 1716-1722 ◽  
Author(s):  
Iwona Wlodarska ◽  
Anna Aventı́n ◽  
Júlia Inglés-Esteve ◽  
Daniela Falzetti ◽  
Arnold Criel ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Acute Lymphoblastic Leukemia ◽  
Fluorescence In Situ Hybridization ◽  
Cell Lines ◽  
Chromosomal Abnormality ◽  
Gene Fusion ◽  
Lymphoblastic Leukemia ◽  
Chronic Myelomonocytic Leukemia ◽  
Myelomonocytic Leukemia

Abstract Translocation t(5; 12)(q33; p13), resulting in an ETV6/PDGFRB gene fusion, is a recurrent chromosomal abnormality associated with chronic myelomonocytic leukemia (CMML). An analogous translocation was also found in four cell lines with features of pre-B acute lymphoblastic leukemia (ALL). Using fluorescence in situ hybridization (FISH) we show here that in three of these cell lines identical complex rearrangements occurred. However, the regions involved on 5q and 12p are different from the breakpoints in CMML, and the translocation is accompanied by seemingly identical cryptic deletions of both 5q and 12p chromosome sequences in all analyzed pre-B ALL cell lines. The similar cytogenetic, FISH, and immunophenotyping findings in the three cell lines suggest that the t(5; 12)(q31q33; p12) defines a new entity of pre-B ALL.

scholarly journals MASSIVE PNEUMONIA AND PANCYTOPENIA LEADING TO THE DIAGNOSIS OF ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILD – A CASE REPORT AND A REVIEW OF THE LITERATURE

2017 ◽  
Vol 66 (3) ◽  
pp. 186-190
Author(s):  
Lorena Elena Melit ◽  
◽  
Cristina Oana Marginean ◽  
Mihaela Ioana Chincesan ◽  
Iulia Armean ◽  
...  
Keyword(s):  
Case Report ◽  
Acute Lymphoblastic Leukemia ◽  
Lymphoblastic Leukemia ◽  
Review Of The Literature

scholarly journals Rhabdomyosarcoma debut masquerading as acute lymphoblastic leukemia: A case report and review of the literature

2019 ◽  
Vol 7 (8) ◽  
pp. 1545-1548
Author(s):  
Bernardo López‐Andrade ◽  
Maria Antonia Duran ◽  
Lourdes Torres ◽  
Marta García‐Recio ◽  
Laura Lo Riso ◽  
...  
Keyword(s):  
Case Report ◽  
Acute Lymphoblastic Leukemia ◽  
Lymphoblastic Leukemia ◽  
Review Of The Literature
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