Genetic structure of the paternal lineage of the Roma People

2011 ◽  
Vol 145 (1) ◽  
pp. 21-29 ◽  
Author(s):  
Horolma Pamjav ◽  
Andrea Zalán ◽  
Judit Béres ◽  
Melinda Nagy ◽  
Yuet Meng Chang
Meta Gene ◽  
2020 ◽  
Vol 26 ◽  
pp. 100797
Author(s):  
Pankaj Shrivastava ◽  
K.P.S. Kushwaha ◽  
R.K. Kumawat ◽  
Tanya Chauhan ◽  
Maria Saiz ◽  
...  

2018 ◽  
Vol 52 (2) ◽  
pp. 127-139
Author(s):  
Ján Ferjenčík

AbstractIntroduction:Psychological assessment of Roma children belongs to the most controversial topics in recent theory and practice of school psychology in Slovakia. The paper discusses the problem from the three main aspects.Discussion:The first of them raises into question the usability of “general intelligence” construct in the assessment practice. It is shown that from the psychometric point of view it is improper to represent couple of qualitatively different attributes by sole number. Moreover, intelligence as a construct refers to general mental achievement of child here and now but it says nothing about the causes and reasons of the achievement.The second part is devoted to the problem of test adaptation. The author draws attention to the fact that Roma people are the minority with own characteristics, including language, style of life, customs and values. Due to this, it is necessary to use in the psychological assessment solely well adapted psychological tests with special norms for Roma children.The third topic discusses the position of psychologists in decision-making with regard to the type of education of a particular child.Limitations:Because education is realized in a broad social context (policy, social attitudes and expectations, material and financial conditions, teaching expertise, etc.), many of these factors are out of psychologists´ direct control and competencies. Due to this, the primary task in the psychological assessment of Roma pupils should not be based on the question about the advisability of their special education. Instead of this, the psychologist should be concerned more on the proper description and explanation of children’s psychological functioning and, following this, on formulating individual and particular recommendations how and what cognitive, emotional or motivational elements it is necessary to develop at school.


Author(s):  
Т.В. Никитина ◽  
А.А. Кашеварова ◽  
М.М. Гридина ◽  
А.А. Хабарова ◽  
А.Г. Мензоров ◽  
...  

Митотическая нестабильность кольцевых хромосом может приводить к появлению клеточных клонов с различной генетической структурой. В качестве модели нестабильности кольцевых хромосом в митозе мы использовали фибробласты от пациентов с r(8), r(13), r(18) и r(22) и полученные из них индуцированные плюрипотентные стволовые клетки (ИПСК). Линии ИПСК с r(22) имели относительно стабильный кариотип на протяжении десятков (до 60) пассажей и сохраняли неизменную структуру кольцевой хромосомы. Кариотип линий ИПСК с r(8) и r(18) на ранних пассажах стабильный, планируется его изучение на поздних пассажах. Наибольшее разнообразие кариотипа выявлено в линиях ИПСК с r(13), в которых наблюдали различные перестройки и выраженную клеточную гетерогенность. Определение факторов, влияющих на митотическую стабильность кольцевых хромосом, может иметь значение для консультирования пациентов. Mitotic instability of ring chromosomes can lead to the appearance of cell clones with different genetic structure. IPSCs from fibroblasts of patients with r(8), r(13), r(18), and r(22) were used as a model of ring chromosomes mitotic behavior. Karyotypes of iPSC lines with r(8) and r(18) have so far been evaluated only in the early passages, lines with r(22) have maintained a relatively stable karyotype up to 60 passages. The occurrence of rearrangements and cellular heterogeneity was found characteristic for r(13) iPSCs. The determination of factors affecting the ring chromosomes mitotic stability would be beneficial for the patient’s prognosis.


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