scholarly journals The Boston Naming Test identifies presymptomatic anomia in MAPT mutation carriers

2021 ◽  
Vol 17 (S6) ◽  
Author(s):  
Arabella Bouzigues ◽  
Lucy L Russell ◽  
Georgia Peakman ◽  
Rhian S Convery ◽  
Caroline V Greaves ◽  
...  
2012 ◽  
Vol 18 (6) ◽  
pp. 1086-1090 ◽  
Author(s):  
Myriam Barandiaran ◽  
Ainara Estanga ◽  
Fermín Moreno ◽  
Begoña Indakoetxea ◽  
Ainhoa Alzualde ◽  
...  

AbstractMutations in the progranulin (PGRN) gene have been identified as a cause of frontotemporal dementia (FTD). However, little is known about the neuropsychological abilities of asymptomatic carriers of these mutations. The aim of the study was to assess cognitive functioning in asymptomatic c.709-1G>A PGRN mutation carriers. We hypothesized that poorer neuropsychological performance could be present before the development of clinically significant FTD symptoms. Thirty-two asymptomatic first-degree relatives of FTD patients carrying the c.709-1G>A mutation served as study participants, including 13 PGRN mutation carriers (A-PGRN+) and 19 non-carriers (PGRN-). A neuropsychological battery was administered. We found that the A-PGRN+ participants obtained significantly poorer scores than PGRN- individuals on tests of attention (Trail-Making Test Part A), mental flexibility (Trail-Making Test Part B), and language (Boston Naming Test). Poorer performance on these tests in asymptomatic PGRN mutation carriers may reflect a prodromal phase preceding the onset of clinically significant symptoms of FTD. (JINS, 2012, 18, 1086–1090)


2018 ◽  
Author(s):  
Ayten Ekinci Soylu ◽  
Banu Cangöz

Assessment ◽  
2020 ◽  
pp. 107319112098392
Author(s):  
Danielle Zimmerman ◽  
J. Attridge ◽  
Summer Rolin ◽  
Jeremy Davis

This study compared prorated Boston Naming Test (BNT-P; omitting the noose item) and standard administration (BNT-S) scores in physical medicine and rehabilitation patients ( N = 480). The sample was 34% female and 91% White with average age and education of 46 ( SD = 15) and 14 ( SD = 3) years, respectively. BNT-P was calculated by summing correct responses excluding item 48 and estimating the 60-item score with cross multiplication and division. BNT-P and BNT-S scores were compared via concordance correlation (CC) coefficients; reflected and log transformed data were examined with equivalence tests. BNT-P and BNT-S scores showed almost perfect agreement (CC = .99). Transformed scores demonstrated equivalence (±1.1 points). Raw and scaled score differences were 0 in 88% and 96% of cases, respectively. Race and ethnicity accounted for item 48 outcomes while controlling for age and education. Findings support the utility of prorated BNT scores in rehabilitation patients.


2018 ◽  
Vol 23 (7) ◽  
pp. 840-850 ◽  
Author(s):  
Daruj Aniwattanapong ◽  
Sookjaroen Tangwongchai ◽  
Thitiporn Supasitthumrong ◽  
Solaphat Hemrunroj ◽  
Chavit Tunvirachaisakul ◽  
...  

Aphasiology ◽  
2018 ◽  
Vol 33 (5) ◽  
pp. 561-578
Author(s):  
JoAnne Savoie ◽  
Kelly Root ◽  
Julie Villers ◽  
Kaitlyn M. Goldsmith ◽  
Matthew Short

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