A Doubly Axially Chiral Phosphoric Acid Catalyst for the Asymmetric Tandem Oxyfluorination of Enamides

2012 ◽  
Vol 124 (38) ◽  
pp. 9822-9826 ◽  
Author(s):  
Takashi Honjo ◽  
Robert J. Phipps ◽  
Vivek Rauniyar ◽  
F. Dean Toste
Keyword(s):  
Phosphoric Acid ◽  
Acid Catalyst ◽  
Chiral Phosphoric Acid ◽  
Axially Chiral

A Doubly Axially Chiral Phosphoric Acid Catalyst for the Asymmetric Tandem Oxyfluorination of Enamides

2012 ◽  
Vol 51 (38) ◽  
pp. 9684-9688 ◽  
Author(s):  
Takashi Honjo ◽  
Robert J. Phipps ◽  
Vivek Rauniyar ◽  
F. Dean Toste
Keyword(s):  
Phosphoric Acid ◽  
Acid Catalyst ◽  
Chiral Phosphoric Acid ◽  
Axially Chiral

ChemInform Abstract: A Doubly Axially Chiral Phosphoric Acid Catalyst for the Asymmetric Tandem Oxyfluorination of Enamides.

ChemInform ◽  
2013 ◽  
Vol 44 (8) ◽  
pp. no-no
Author(s):  
Takashi Honjo ◽  
Robert J. Phipps ◽  
Vivek Rauniyar ◽  
F. Dean Toste
Keyword(s):  
Phosphoric Acid ◽  
Acid Catalyst ◽  
Chiral Phosphoric Acid ◽  
Axially Chiral

The Highly Enantioselective Addition of Indoles toN-Acyl Imines with Use of a Chiral Phosphoric Acid Catalyst

2007 ◽  
Vol 9 (14) ◽  
pp. 2609-2611 ◽  
Author(s):  
Gerald B. Rowland ◽  
Emily B. Rowland ◽  
Yuxue Liang ◽  
Jason A. Perman ◽  
Jon C. Antilla
Keyword(s):  
Phosphoric Acid ◽  
Acid Catalyst ◽  
Chiral Phosphoric Acid ◽  
Enantioselective Addition

scholarly journals Recent advances in the asymmetric phosphoric acid-catalyzed synthesis of axially chiral compounds

2021 ◽  
Vol 17 ◽  
pp. 2729-2764
Author(s):  
Alemayehu Gashaw Woldegiorgis ◽  
Xufeng Lin
Keyword(s):  
Phosphoric Acid ◽  
Asymmetric Catalysis ◽  
Medicinal Chemistry ◽  
High Efficiency ◽  
Biologically Active ◽  
Chiral Compounds ◽  
Chiral Phosphoric Acid ◽  
Wide Range ◽  
Axially Chiral ◽  
Acid Catalyzed

In recent years, the synthesis of axially chiral compounds has received considerable attention due to their extensive application as biologically active compounds in medicinal chemistry and as chiral ligands in asymmetric catalysis. Chiral phosphoric acids are recognized as efficient organocatalysts for a variety of enantioselective transformations. In this review, we summarize the recent development of chiral phosphoric acid-catalyzed synthesis of a wide range of axially chiral biaryls, heterobiaryls, vinylarenes, N-arylamines, spiranes, and allenes with high efficiency and excellent stereoselectivity.

scholarly journals QM/MM study on the enantioselectivity of spiroacetalization catalysed by an imidodiphosphoric acid catalyst: how confinement works

2016 ◽  
Vol 14 (11) ◽  
pp. 3031-3039 ◽  
Author(s):  
Luis Simón ◽  
Robert S. Paton
Keyword(s):  
Phosphoric Acid ◽  
Acid Catalyst ◽  
Acid Catalysts ◽  
Chiral Phosphoric Acid

An explanation of why confined imidodiphosphoric acid catalyst succeeds where other chiral phosphoric acid catalysts fail.

Chiral phosphoric acid catalyzed atroposelective and diastereoselective synthesis of 9-aryltetrahydroacridines

2020 ◽  
Vol 7 (16) ◽  
pp. 2255-2262 ◽  
Author(s):  
You-Dong Shao ◽  
Dan-Dan Han ◽  
Wen-Yue Ma ◽  
Dao-Juan Cheng
Keyword(s):  
Phosphoric Acid ◽  
Diastereoselective Synthesis ◽  
Chiral Phosphoric Acid ◽  
Axially Chiral ◽  
Acid Catalyzed

A chiral phosphoric acid catalyzed atroposelective annulation between 2-aminoaryl ketones and alicyclic ketones has been developed to access a new library of enantioenriched axially chiral 9-aryltetrahydroacridines.

scholarly journals A chiral phosphoric acid catalyst for asymmetric construction of 1,3-dioxanes

2015 ◽  
Vol 51 (58) ◽  
pp. 11693-11696 ◽  
Author(s):  
Akira Matsumoto ◽  
Keisuke Asano ◽  
Seijiro Matsubara
Keyword(s):  
Phosphoric Acid ◽  
Michael Addition ◽  
Acid Catalyst ◽  
Chiral Phosphoric Acid

A chiral phosphoric acid catalyst enabled enantioselective 1,3-dioxane construction, useful for polyketide motif synthesis, via a hemiacetalization/intramolecular oxy-Michael addition cascade.

Asymmetric synthesis of atropisomeric pyrazole via an enantioselective reaction of azonaphthalene with pyrazolone

2019 ◽  
Vol 55 (84) ◽  
pp. 12715-12718 ◽  
Author(s):  
Huijun Yuan ◽  
Yao Li ◽  
Hanhui Zhao ◽  
Zhihong Yang ◽  
Xin Li ◽  
...  
Keyword(s):  
Phosphoric Acid ◽  
Asymmetric Synthesis ◽  
Pyrazole Derivatives ◽  
Asymmetric Reaction ◽  
Chiral Phosphoric Acid ◽  
Wide Range ◽  
Axially Chiral ◽  
Enantioselective Reaction ◽  
Catalytic Asymmetric

The first catalytic asymmetric reaction of azonaphthalene with pyrazolone has been established. A wide range of axially chiral pyrazole derivatives have been achieved in good yields (68–99%) with excellent enantioselectivities (83–98% ee) by utilizing chiral phosphoric acid as a catalyst.

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