Spiroacetal Formation through Telescoped Cycloaddition and Carbon-Hydrogen Bond Functionalization: Total Synthesis of Bistramide A

2014 ◽  
Vol 126 (41) ◽  
pp. 11255-11258 ◽  
Author(s):  
Xun Han ◽  
Paul E. Floreancig
Keyword(s):  
Hydrogen Bond ◽  
Total Synthesis ◽  
Bond Functionalization ◽  
Bistramide A

Organophotoredox-Catalyzed C–H Alkylation of Imidazoheterocycles with Malonates: Total Synthesis of Zolpidem

Synthesis ◽  
2020 ◽  
Author(s):  
Narendra R. Chaubey ◽  
Anant R. Kapdi ◽  
Biswanath Maity
Keyword(s):  
Total Synthesis ◽  
Room Temperature ◽  
Drug Molecule ◽  
Bond Functionalization ◽  
First Report ◽  
Mild Conditions ◽  
The Past ◽  
Hypnotic Drug ◽  
Free Environment

AbstractOrganophotocatalytic C–H bond functionalization has attracted a lot of attention in the past several years due to the possibility of catalyzing reactions in a metal- and peroxide-free environment. Continuing on these lines, an organophotoredox-catalyzed C–H functionalization of imidazo[1,2-a]pyridines and related heterocycles with bromomalonates under mild conditions is reported, providing excellent yields of the products at room temperature. This is the first report involving malonates as coupling partners leading to the synthesis of a range of functionalized products including total synthesis of zolpidem, a sedative­-hypnotic drug molecule.

scholarly journals Total Synthesis of Bistramide A.

ChemInform ◽  
2007 ◽  
Vol 38 (21) ◽  
Author(s):  
Jason T. Lowe ◽  
Iwona E. Wrona ◽  
James S. Panek
Keyword(s):  
Total Synthesis ◽  
Bistramide A

Total Synthesis of Bistramide A

2007 ◽  
Vol 9 (2) ◽  
pp. 327-330 ◽  
Author(s):  
Jason T. Lowe ◽  
Iwona E. Wrona ◽  
James S. Panek
Keyword(s):  
Total Synthesis ◽  
Bistramide A
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