Supramolecular Complexes of Flexible, Extended Cavity Calix[4]arenes?Structural Characterization of a Molecular Venus Flytrap

The synthesis of bis-(1-carboranylmethyl) ether was first published in 1963; however, its subsequent complexation with a transition metal was never reported. We now report the complexation of cobalt and the corresponding X-ray structure for the triphenylmethylphosphonium salt of the cobalta-bis(carboranylmethyl) ether. The cobalt complex crystallized in the monoclinic space group C2/c with a = 21.729(6) Å, b = 9.845(2) Å, c = 35.565(9) Å, β = 105.363(9)°, V = 7336 Å3, and Z = 8. Data were collected using CuKα radiation, to a maximum 2θ = 115°, giving 4123 unique reflections, and the structure was solved by heavy atom methods. The final discrepancy index was R = 0.093, Rw = 0.100 for 1919 independent reflections with I > 3σ(I). This metala-bis(carboranylalkyl) ether is the first in a new class of Venus flytrap compounds (VFC), containing an ether linkage, to be synthesized as model compounds for the development of reagents suitable for use in the radioimmunodetection and radioimmunotherapy of cancer. Keywords: cobalt, radioimmunodetection, radioimmunotherapy, Venus flytrap.

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Structural characterization of inclusion complexes of para-sulphonato-calix[8]arene with 1,2-bis(4-pyridyl)-ethane and 1,3-bis(4-pyridyl)-propane. New ‘double cone’ and ‘up–flat–down’ conformations of para-sulphonato-calix[8]arene

CrystEngComm ◽

10.1039/c3ce42303d ◽

2014 ◽

Vol 16 (21) ◽

pp. 4399-4405 ◽

Cited By ~ 9

Author(s):

B. Lesniewska ◽

F. Perret ◽

K. Suwinska ◽

A. W. Coleman

Keyword(s):

Inclusion Complexes ◽

Structural Characterization ◽

Double Cone ◽

Supramolecular Complexes

Two new conformations of para-sulphonato-calix[8]arene have been found in supramolecular complexes with BPE and BPP, the gas take-up has been demonstrated for S8C–BPE complex.

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Synthesis and structural characterization of pyrazole-bridged metalla-bis(dicarbollide) derivatives of cobalt, nickel, copper, and iron: models for venus flytrap cluster reagents

Journal of the American Chemical Society ◽

10.1021/ja00049a035 ◽

1992 ◽

Vol 114 (23) ◽

pp. 9003-9011 ◽

Cited By ~ 33

Author(s):

Aravamuthan Varadarajan ◽

Stephen E. Johnson ◽

Frank A. Gomez ◽

Sarmistha Chakrabarti ◽

Carolyn B. Knobler ◽

...

Keyword(s):

Structural Characterization ◽

Venus Flytrap ◽

Cobalt Nickel ◽

Nickel Copper ◽

Derivatives Of

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Synthesis and structural characterization of three hydrogen-bonding connected supramolecular complexes of nickel, zinc and copper with 1,3-diphenyl-4-(salicylidene hydrazide)-acetyl-pyrazolone-5 and 2,2′-bipyridine

Inorganica Chimica Acta ◽

10.1016/j.ica.2005.10.013 ◽

2006 ◽

Vol 359 (2) ◽

pp. 633-641 ◽

Cited By ~ 25

Author(s):

Xin Hu ◽

Li Zhang ◽

Lang Liu ◽

Guangfei Liu ◽

Dianzeng Jia ◽

...

Keyword(s):

Hydrogen Bonding ◽

Structural Characterization ◽

Supramolecular Complexes ◽

Nickel Zinc

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New ultrastructural findings about Borrelia burgdorferi by cryofixation, negative staining, thin sectioning and scanning techniques

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100160467 ◽

1990 ◽

Vol 48 (3) ◽

pp. 582-583

Author(s):

S. F. Hayes ◽

M. D. Corwin ◽

T. G. Schwan ◽

D. W. Dorward ◽

W. Burgdorfer

Keyword(s):

Lyme Disease ◽

Borrelia Burgdorferi ◽

Structural Characterization ◽

Negative Staining ◽

Low Speed ◽

Thin Sectioning ◽

Ultrastructural Findings

Characterization of Borrelia burgdorferi strains by means of negative staining EM has become an integral part of many studies related to the biology of the Lyme disease organism. However, relying solely upon negative staining to compare new isolates with prototype B31 or other borreliae is often unsatisfactory. To obtain more satisfactory results, we have relied upon a correlative approach encompassing a variety EM techniques, i.e., scanning for topographical features and cryotomy, negative staining and thin sectioning to provide a more complete structural characterization of B. burgdorferi.For characterization, isolates of B. burgdorferi were cultured in BSK II media from which they were removed by low speed centrifugation. The sedimented borrelia were carefully resuspended in stabilizing buffer so as to preserve their features for scanning and negative staining. Alternatively, others were prepared for conventional thin sectioning and for cryotomy using modified procedures. For thin sectioning, the fixative described by Ito, et al.

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