scholarly journals Frontispiece: A Tandem In Situ Peptide Cyclization through Trifluoroacetic Acid Cleavage

2014 ◽  
Vol 53 (36) ◽  
pp. n/a-n/a
Author(s):  
Koushik Chandra ◽  
Tapta Kanchan Roy ◽  
Deborah E. Shalev ◽  
Abraham Loyter ◽  
Chaim Gilon ◽  
...  
Keyword(s):  
Trifluoroacetic Acid ◽  
Peptide Cyclization ◽  
Acid Cleavage

A Tandem In Situ Peptide Cyclization through Trifluoroacetic Acid Cleavage

2014 ◽  
Vol 126 (36) ◽  
pp. 9604-9609 ◽  
Author(s):  
Koushik Chandra ◽  
Tapta Kanchan Roy ◽  
Deborah E. Shalev ◽  
Abraham Loyter ◽  
Chaim Gilon ◽  
...  
Keyword(s):  
Trifluoroacetic Acid ◽  
Peptide Cyclization ◽  
Acid Cleavage

Frontispiz: A Tandem In Situ Peptide Cyclization through Trifluoroacetic Acid Cleavage

2014 ◽  
Vol 126 (36) ◽  
pp. n/a-n/a
Author(s):  
Koushik Chandra ◽  
Tapta Kanchan Roy ◽  
Deborah E. Shalev ◽  
Abraham Loyter ◽  
Chaim Gilon ◽  
...  
Keyword(s):  
Trifluoroacetic Acid ◽  
Peptide Cyclization ◽  
Acid Cleavage

A Tandem In Situ Peptide Cyclization through Trifluoroacetic Acid Cleavage

2014 ◽  
Vol 53 (36) ◽  
pp. 9450-9455 ◽  
Author(s):  
Koushik Chandra ◽  
Tapta Kanchan Roy ◽  
Deborah E. Shalev ◽  
Abraham Loyter ◽  
Chaim Gilon ◽  
...  
Keyword(s):  
Trifluoroacetic Acid ◽  
Peptide Cyclization ◽  
Acid Cleavage

scholarly journals Investigation on the reactivity of α-azidochalcones with carboxylic acids: Formation of α-amido-1,3-diketones and highly substituted 2-(trifluoromethyl)oxazoles

2015 ◽  
Vol 11 ◽  
pp. 2021-2028 ◽  
Author(s):  
Kandasamy Rajaguru ◽  
Arumugam Mariappan ◽  
Rajendran Suresh ◽  
Periasamy Manivannan ◽  
Shanmugam Muthusubramanian
Keyword(s):  
Microwave Irradiation ◽  
Carboxylic Acids ◽  
Trifluoroacetic Acid ◽  
Solvent Free ◽  
Solvent Free Conditions ◽  
In Situ Formation ◽  
Lower Temperature

The reaction of α-azidochalcones with carboxylic acids has been investigated resulting in the formation of α-amido-1,3-diketones under microwave irradiation via in situ formation of 2H-azirine intermediates. An interesting reaction is described wherein, with trifluoroacetic acid at lower temperature, it affords highly substituted 2-(trifluoromethyl)oxazoles. These flexible transformations proceed under solvent free conditions in good to excellent yields without any catalyst.

Synthesis and structure of a stegane from dimethylmatairesinol

1984 ◽  
Vol 37 (8) ◽  
pp. 1775 ◽  
Author(s):  
RC Cambie ◽  
GR Clark ◽  
PA Craw ◽  
PS Rutledge ◽  
PD Woodgate
Keyword(s):  
Trifluoroacetic Acid ◽  
Oxidative Coupling ◽  
Boron Trifluoride ◽  
Boron Trifluoride Etherate ◽  
High Yield ◽  
X Ray Diffraction ◽  
X Ray

Oxidative coupling of dimethylmatairesinol with thallium tristrifluoroacetate (prepared in situ from thallium(III) oxide and trifluoroacetic acid) and boron trifluoride etherate gives a high yield of an isostegane which has been isomerized thermally to a stegane. Stereochemical assignments have been confirmed by X-ray diffraction studies.

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