Controlled Release of a Micelle Payload via Sequential Enzymatic and Bioorthogonal Reactions in Living Systems

2019 ◽  
Vol 58 (19) ◽  
pp. 6366-6370 ◽  
Author(s):  
Karine Porte ◽  
Brigitte Renoux ◽  
Elodie Péraudeau ◽  
Jonathan Clarhaut ◽  
Balkis Eddhif ◽  
...  
Keyword(s):  
Controlled Release ◽  
Living Systems ◽  
Bioorthogonal Reactions

Controlled Release of a Micelle Payload via Sequential Enzymatic and Bioorthogonal Reactions in Living Systems

2019 ◽  
Vol 131 (19) ◽  
pp. 6432-6436 ◽  
Author(s):  
Karine Porte ◽  
Brigitte Renoux ◽  
Elodie Péraudeau ◽  
Jonathan Clarhaut ◽  
Balkis Eddhif ◽  
...  
Keyword(s):  
Controlled Release ◽  
Living Systems ◽  
Bioorthogonal Reactions

scholarly journals Synergistic enzymatic and bioorthogonal reactions for selective prodrug activation in living systems

2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Qingxin Yao ◽  
Feng Lin ◽  
Xinyuan Fan ◽  
Yanpu Wang ◽  
Ye Liu ◽  
...  
Keyword(s):  
Living Systems ◽  
Prodrug Activation ◽  
Bioorthogonal Reactions

Redox Reactions in Lipid Membranes as a Model for Primordial Energy-Conserving Systems

1997 ◽  
Vol 161 ◽  
pp. 437-442
Author(s):  
Salvatore Di Bernardo ◽  
Romana Fato ◽  
Giorgio Lenaz
Keyword(s):  
Experimental Evidence ◽  
Lipid Membranes ◽  
Energy Supply ◽  
Redox Reactions ◽  
Living Systems ◽  
Asymmetric Distribution ◽  
Conservation Of Energy ◽  
Asymmetrical Distribution ◽  
Energy Conserving ◽  
Living Organisms

AbstractOne of the peculiar aspects of living systems is the production and conservation of energy. This aspect is provided by specialized organelles, such as the mitochondria and chloroplasts, in developed living organisms. In primordial systems lacking specialized enzymatic complexes the energy supply was probably bound to the generation and maintenance of an asymmetric distribution of charged molecules in compartmentalized systems. On the basis of experimental evidence, we suggest that lipophilic quinones were involved in the generation of this asymmetrical distribution of charges through vectorial redox reactions across lipid membranes.

Prolonged Fixation Studies For Spaceflight

1973 ◽  
Vol 31 ◽  
pp. 332-333
Author(s):  
Robert Corbett ◽  
Delbert E. Philpott ◽  
Sam Black
Keyword(s):  
High Pressure ◽  
Living Systems ◽  
Prolonged Storage ◽  
Time Intervals ◽  
Early Signs ◽  
Large Numbers

Observation of subtle or early signs of change in spaceflight induced alterations on living systems require precise methods of sampling. In-flight analysis would be preferable but constraints of time, equipment, personnel and cost dictate the necessity for prolonged storage before retrieval. Because of this, various tissues have been stored in fixatives and combinations of fixatives and observed at various time intervals. High pressure and the effect of buffer alone have also been tried.Of the various tissues embedded, muscle, cartilage and liver, liver has been the most extensively studied because it contains large numbers of organelles common to all tissues (Fig. 1).

Controlled release antibiotics for dry powder lung delivery

2009 ◽  
Vol 00 (00) ◽  
pp. 090805050810080-8 ◽  
Author(s):  
Handoko Adi ◽  
Paul Michael Young ◽  
Hak-Kim Chan ◽  
Rania Salama ◽  
Daniela Traini
Keyword(s):  
Controlled Release ◽  
Dry Powder ◽  
Lung Delivery

Positive health and living systems frameworks.

1990 ◽  
Vol 45 (8) ◽  
pp. 980-981 ◽  
Author(s):  
Donald H. Ford
Keyword(s):  
Living Systems ◽  
Positive Health
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